Statistical Mechanics of Force-Induced Transitions of Biopolymers

  • Sanjay Kumar
Living reference work entry


Single molecule force spectroscopy constitutes a robust method for probing the unfolding of biomolecules. Knowledge gained from statistical mechanics is helping to build our understanding about more complex structure and function of biopolymers. Here, we have review some of the models and techniques that have been employed to study force-induced transitions in biopolymers. We briefly describe the merit and limitation of these models and techniques. In this context, we discuss statistical models of polymer along with numerical techniques, which may provide enhanced insight in understanding the unfolding of biomolecules.


Partition Function Monte Carlo Exclude Volume Effect Verlet Algorithm Gaussian Chain 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



We would like to thank D. Giri, A. R. Singh, and G. Mishra for many helpful discussions. Financial assistance from the Department of Science and Technology, New Delhi is gratefully acknowledged.


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Copyright information

© Springer Science+Business Media Dordrecht 2015

Authors and Affiliations

  1. 1.Department of PhysicsBanaras Hindu UniversityVaranasiIndia

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