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Mixture Effects in Ecotoxicology

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Encyclopedia of Aquatic Ecotoxicology

Synonyms

Mixture ecotoxicity; Multiple stressor ecotoxicity

Glossary

Antagonism:

A class of interactive joint action between compounds where the potency effects of the mixture are lower than expected, i.e., where the joint action is interactive.

Assessment endpoint:

Parameter measured after a test exposure on a given organism, e.g., mortality and reproduction. A measurement endpoint designates calculated values such as NOEC or EC50.

Baseline toxicity:

Baseline toxicity is the minimal toxicity of any given chemical. It is due to a nonspecific mode of action that exerts a narcotic toxicity. For example, the toxicity of triazines on insects or fish can be seen as baseline toxicity. Indeed triazines act as photosynthesis inhibitors, but this process has no effect on these organisms.

Concentration addition (CA):

The concentration addition (or dose addition) model is commonly used to predict mixture toxicity for similarly acting compounds (with a similar mode of toxic action). This concept...

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Correspondence to Nathalie Chèvre .

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Chèvre, N., Gregorio, V. (2013). Mixture Effects in Ecotoxicology. In: Férard, JF., Blaise, C. (eds) Encyclopedia of Aquatic Ecotoxicology. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-5704-2_67

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