Abstract
Neuroenhancement through psychopharmacology can improve a range of cognitive and affective functions involved in practical and moral reasoning and decision-making. In this chapter, the claim that this type of enhancement would adversely alter human nature will be examined, and it will be argued that the claim is unfounded because it is based on questionable assumptions. In addition, some of the neurobiological risks associated with cognition-enhancing drugs will be considered. It will be pointed out that answers to questions about risk can only be provided after a sufficient number of prospective controlled studies of the drugs’ effects have been conducted. On the basis of studies conducted thus far, less pronounced effects of these drugs on the cognitively better off and more pronounced effects on the cognitively worse off suggest that they would not increase and might decrease social inequality. Finally, empirical evidence for the potential of drugs to enhance moral sensitivity and moral motivation will be considered and some of the social implications of the effects of the drugs will be explored. If the drugs were effective in making us more responsive to moral reasons for and against beneficial and harmful actions and promoted moral progress, there would remain the question of how to balance the collective interest against individuals’ right to choose not to enhance.
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References
Bartz, J., et al. (2011). Social effects of oxytocin in humans: Context and person matter. Trends in Cognitive Sciences, 15, 301–309.
Beauchamp, T., & Childress, J. (2008). Principles of biomedical ethics (6th ed.). New York: Oxford University Press.
Buchanan, A. (2009). Human nature and enhancement. Bioethics, 23, 141–150.
Buchanan, A. (2011a). Beyond humanity? The ethics of biomedical enhancement. New York: Oxford University Press.
Buchanan, A. (2011b). Better than human: The promise and perils of enhancing ourselves. New York: Oxford University Press.
Chan, S., & Harris, J. (2011). Moral enhancement and pro-social behavior. Journal of Medical Ethics, 37, 130–131.
Crockett, M., et al. (2010). Serotonin selectively influences moral judgment and behavior through effects on harm aversion. Proceedings of the National Academy of Sciences, 107, 17433–17438.
de Jongh, R., et al. (2008). Botox for the brain: Enhancement of cognition, mood and pro-social behavior and blunting of unwanted memories. Neuroscience and Biobehavioral Reviews, 32, 760–776.
Douglas, T. (2008). Moral enhancement. Journal of Applied Philosophy, 25, 228–245.
Elliott, R., et al. (1997). Effects of methylphenidate on spatial working memory and planning in healthy young adults. Psychopharmacology, 131, 196–206.
Farah, M., et al. (2004). Neurocognitive enhancement: What can we do and what should we do? Nature Reviews Neuroscience, 5, 421–425.
Forlini, C., et al. (2012). Should physicians prescribe cognitive enhancers to healthy individuals? Canadian Medical Association Journal. doi:10.1503/cmaj.121508.
Fournier, J., et al. (2010). Antidepressant drug effects and depression severity: A patient-level meta-analysis. Journal of the American Medical Association, 303, 47–53.
Greely, H., et al. (2008). Towards responsible use of cognitive-enhancing drugs by the healthy. Nature, 456, 702–705.
Habermas, J. (2003). The future of human nature. Cambridge, UK: Polity Press.
Harris, J. (2007). Enhancing evolution: The ethical case for making better people. Princeton: Princeton University Press.
Harris, J. (2011). Moral enhancement and freedom. Bioethics, 25, 102–111.
Harris, J. (2012). Moral progress and moral enhancement. Bioethics. doi:10.1111/j.1467-8519. 2012. 01965.x.
Hauskeller, M. (2011). Human enhancement and the giftedness of life. Philosophical Papers, 40, 55–79.
Heinz, A., et al. (2012). Cognitive neuroenhancement: False assumptions in the ethical debate. Journal of Medical Ethics, 38, 372–375.
Hyman, S. (2012). Might stimulant drugs support moral agency in ADHD children? Journal of Medical Ethics. doi:10.1136/medethics-2012-100846.
Juengst, E. (1998). What does enhancement mean? In E. Parens (Ed.), Enhancing human traits: Ethical and social implications (pp. 29–47). Washington, DC: Georgetown University Press.
Kass, L. (2003). Beyond therapy: Biotechnology and the pursuit of happiness. New York: Harper Collins.
Kirsch, I., et al. (2008). Initial severity and antidepressant benefits: A met-analysis of data submitted to the Food and Drug Administration. PLoS Medicine, 5(1), e45.
LeDoux, J. (1996). The emotional brain. New York: Simon & Schuster.
Lucke, J., et al. (2011). Deflating the neuroenhancement bubble. AJOB Neuroscience, 2(4), 38–43.
Maher, B. (2008). Poll results: Look who’s doping. Nature, 452, 674–675.
McCabe, S., et al. (2005). Non-medical use of prescription stimulants among US college students: Prevalence and correlates from a national survey. Addiction, 100, 96–106.
Merkel, R., et al. (2007). Intervening in the brain: Changing psyche and society. Berlin: Springer.
Persson, I., & Savulescu, J. (2011). Getting moral enhancement right: The desirability of moral bioenhancement. Bioethics. doi:10.1111/j.1467-8519.2011.01907.x.
Persson, I., & Savulescu, J. (2012). Unfit for the future: The need for moral enhancement. Oxford: Oxford University Press.
Repantis, D., et al. (2010). Modafinil and methylphenidate for neuroenhancement in healthy individuals: A systematic review. Pharmacological Research, 62, 187–206.
Ross, H., & Young, L. (2009). Oxytocin and the neural mechanisms regulating social cognition and affiliative behavior. Frontiers in Neuroendocrinology, 30, 534–547.
Sahakian, B., & Morein-Zamir, S. (2007). Professor’s little helper. Nature, 450, 1157–1159.
Sandel, M. (2007). The case against perfection: Ethics in the Age of genetic engineering. Cambridge, MA: Harvard University Press.
Scheffler, R., et al. (2009). Positive association between attention-deficit/hyperactivity disorder medication use and academic achievement during elementary school. Pediatrics, 123, 1273–1279.
Spence, S. (2008). Can pharmacology help enhance human morality? The British Journal of Psychiatry, 193, 179–180.
Stahl, S. (2006). Essential psychopharmacology (2nd ed.). New York: Cambridge University Press.
Synofzik, M. (2009). Ethically justified, clinically applicable criteria for physician decision- making in psychopharmacological enhancement. Neuroethics, 2(2), 89–102.
Tannsjo, T. (2009). Ought we to enhance our cognitive capacities? Bioethics, 23, 421–432.
Volkow, N., et al. (2009). Effects of modafinil on dopamine and dopamine transporters in the male human brain. Journal of the American Medical Association, 301, 1148–1154.
Wilens, T., et al. (2008). Misuse and diversion of stimulants prescribed for ADHD: A systematic review of the literature. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 21–31.
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The author is grateful to Bert Gordijn for helpful comments on an earlier version of this chapter.
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Glannon, W. (2015). Reflections on Neuroenhancement. In: Clausen, J., Levy, N. (eds) Handbook of Neuroethics. Springer, Dordrecht. https://doi.org/10.1007/978-94-007-4707-4_93
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DOI: https://doi.org/10.1007/978-94-007-4707-4_93
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