Encyclopedia of Food and Agricultural Ethics

2014 Edition
| Editors: Paul B. Thompson, David M. Kaplan

GM Food, Nutrition, Safety, and Health

  • Lise Nordgard
  • Idun Merete Gronsberg
  • Anne Ingeborg Myhr
Reference work entry
DOI: https://doi.org/10.1007/978-94-007-0929-4_3


Agriculture; Ethics; Food science; GM crops; GM foods; Risk; Socioeconomics


Research on and development of genetically modified organisms (GMOs) has been facilitated by modern biotechnological techniques. The first GM plant, a tobacco plant expressing an antibiotic resistance gene taken from a bacterium, was grown in a greenhouse in 1983. Since then a variety of GM crop plants have been released into agricultural fields. At present, herbicide-resistant crops are the most widely grown GM plants (approximately 70 %). These GM crops contain genes that enable them to degrade ingredients in herbicides and imply that farmers can control weeds by herbicides as well as low tillage practices. Genes from the Bacillus thuringiensishave been inserted in plants to make them resist insect attacks and are the second most popular GM crops at the market together with plants that contain stacked genes, a combination of herbicide tolerance and insect resistance. At present, there...

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  1. Benbrook, C. (2009). Impacts of genetically engineered crops on pesticide use: The first thirteen years. The Organic Center. http://www.organic-center.org/reportfiles/GE13YearsReport.pdf. Accessed 13 Mar 2013.
  2. Botha, G. M., & Viljoen, C. D. (2008). Can GM sorghum impact Africa? Trends in Biotechnology, 26(2), 64–69.Google Scholar
  3. De Schrijver, A., Devos, Y., Van den Blucke, M., Cadot, P., De Loose, M., Reheul, D., & Sneyer, M. (2007). Risk assessment of GM stacked events obtained from crosses between GM Events. Trends in Food Science & Technology, 18, 101–109.Google Scholar
  4. Domingo, J. L. (2007). Toxicity studies of genetically modified plants: a review of the published literature. Critical Reviews in Food Science and Nutrition, 47, 721–733.Google Scholar
  5. EFSA. (2008). Safety and nutritional assessment of GM plants and derived from food and feed. The role of animal feeding trials. Food and Chemical Toxicology, 46, A2–A70.Google Scholar
  6. EFSA. (2011). Guidance for risk assessment of food and feed from genetically modified plants. EFSA Journal, 9(5), 2150.Google Scholar
  7. Freese, W., & Schubert, D. (2004). Safety testing and regulation of genetically engineered foods. Biotechnology & Genetic Engineering Reviews, 21, 299–324.Google Scholar
  8. Gassmann, A. J., Petzold-Maxwell, J. L., Keweshan, R. S., & Dunbar, M. W. (2011). Field-evolved resistance to Bt maize by western corn rootworm. PLoS ONE, 6(7), e22629. doi:10.1371/journal.pone.0022629.Google Scholar
  9. Gomord, V., Chamberlain, P., Jefferis, R., & Faye, L. (2005). Biopharmaceutical production in plants: Problems, solutions and opportunities. Trends in Biotechnology, 23, 559–565.Google Scholar
  10. Heinemann, J. A., Kurenbach, B., & Quist, D. (2011). Molecular profiling – A tool for addressing emerging gaps in the comparative risk assessment of GMOs. Environment International, 37, 1285–1293.Google Scholar
  11. ISAAA (International Service for the Acquisition of agri-biotech applications) (2013). ISAAA brief 44-2012. http://www.isaaa.org. Accessed 26 March 2013.
  12. Küster, B., Krogh, T. N., Mørtz, E., & Harvey, D. J. (2001). Glycosylation analysis of gel-separated proteins. Proteomics, 1, 350–361.Google Scholar
  13. Melo-Martin, I., & Meghani, Z. (2008). Beyond risk. A more realistic risk-benefit analysis of agricultural biotechnologies. EMBO Reports, 9, 302–306.Google Scholar
  14. Nielsen, K. M. (2013). Biosafety data as confidential business information. PLoS Biology, 11, e1001499. doi:10.1371/journal.pbio.1001499.Google Scholar
  15. Omenn, G. S., Goodman, G. E., Thornquist, M. D., et al. (1996). Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. New England Journal of Medicine, 334, 1150–1155.Google Scholar
  16. Rosendal, K. G., & Myhr, A. I. (2009). GMO assessment in Norway: Societal utility and sustainable development. EMBO Reports, 10, 939–940.Google Scholar
  17. Séralini, G. E., Clair, E., Mesnage, R., Gress, S., Defarge, N., Malatesta, M., Hennequin, D., & de Vendômois, J. S. (2012). Long-term toxicity of a roundup herbicide and a roundup-tolerant genetically modified maize. Food and Chemical Toxicology, 50(11), 4221–4231. doi:10.1016/j.fct.2012.08.005.Google Scholar
  18. Spök, A., Gaugitsch, H., Laffer, S., Pauli, G., Saito, H., Sampson, H., Sibanda, E., Thomas, E., van Hage, M., & Valenta, R. (2005). Suggestions for the assessment of the allergenic potential of genetically modified organisms. International Archives of Allergy and Immunology, 137, 167–180.Google Scholar
  19. Thompson, P. (2007). Food and biotechnology in ethical perspective. Dordrecht: Springer.Google Scholar
  20. VKM (Norwegian Scientific Committee for Food Safety). (2005). An assessment on potential long-term effects caused by antibiotic resistance marker genes in genetically modified organisms based on antibiotic usage and resistance patterns in Norway. Report from an Ad Hoc Group. Oslo, Norway.Google Scholar
  21. WCED (World Commission on Environment and Development). (1987). Our common future. New York: Oxford University Press.Google Scholar
  22. WHO (2002). Foods derived from modern technology: 20 questions on genetically modified foods (available at: htpp://www.who.int/fsf/GMfood/).

Copyright information

© Springer Science+Business Media Dordrecht 2014

Authors and Affiliations

  • Lise Nordgard
    • 1
  • Idun Merete Gronsberg
    • 1
  • Anne Ingeborg Myhr
    • 1
  1. 1.GenØk-Centre of BiosafetyTromsøNorway