Quantitative Structure–Activity Relationships of Antimicrobial Compounds

  • F. P. Maguna
  • N. B. Okulik
  • Eduardo A. Castro
Reference work entry


A thorough antimicrobial review of an increasing number of reports reveals a broad spectrum of research activity in the development practices that are used to treat a variety of diseases. The quantitative relationship between chemical structure and biological activity has received considerable attention in recent years because it allows one to predict theoretically bioactivity without an inordinate amount of experimental time and effort. In this chapter we collect and discuss critically published results concerning the QSAR research on antimicrobial compounds. Finally, we present an updated perspective about the future trends in this area.


Antimicrobial Activity Molecular Descriptor Coumarin Derivative Cinnamic Acid Derivative Oral Malodor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media B.V. 2012

Authors and Affiliations

  • F. P. Maguna
    • 1
  • N. B. Okulik
    • 1
  • Eduardo A. Castro
    • 1
  1. 1.Facultad de AgroindustriasUniversidad Nacional del NordesteChacoArgentina

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