Synonyms
Definition
Nanoencapsulation is defined as the entrapping of active ingredients in nanometer-sized capsules.
Overview
Nanoencapsulation is defined as the technology of packaging nanoparticles of solid, liquid, or gas, also known as the core or active, within a secondary material, named as the matrix or shell, to form nanocapsules (see Fig. 1) [1]. The core contains the active ingredient (e.g., drugs, perfumes, biocides, vitamins, etc., see Table 1), while the shell isolates and protects the core from the surrounding environment. This protection can be permanent or temporal, in which case the core is generally released by diffusion or in response to a trigger, such as shear, pH, or enzyme action, thus enabling their controlled and timed delivery to a targeted site [2, 3].
Scheme of a nanocapsule
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References
Augustin, M.A., Hemar, Y.: Nano- and micro-structured assemblies for encapsulation of food ingredients. Chem. Soc. Rev. 38, 902–912 (2009)
Desai, K.G.H., Park, H.J.: Recent developments in microencapsulation of food ingredients. Dry Technol. 23, 1361–1394 (2005)
Jyothi, N.V.N., Prasanna, P.M., Sakarkar, S.N., Prabha, K.S., Ramaiah, P.S., Srawan, G.Y.: Microencapsulation techniques, factors influencing encapsulation efficiency. J. Microencapsul. 27, 187–197 (2010)
Ciobanu, M., Heurtault, B., Schultz, P., Ruhlmann, C., Muller, C.D., Frisch, B.: Layersome: development and optimization of stable liposomes as drug delivery system. Int. J. Pharm. 344, 154–157 (2007)
Imaz, I., Rubio-Martinez, M., Garcia-Fernandez, L., Garcia, F., Ruiz-Molina, D., Hernando, J., Puntes, V., Maspoch, D.: Coordination polymer particles as potential drug delivery systems. Chem. Commun. 46, 4737–4739 (2010)
Jaworek, A.: Electrostatic micro- and nanoencapsulation and electroemulsification: A brief review. J. Microencapsul. 25, 443–468 (2008)
Wooster, T.J., Golding, M., Sanguansri, P.: Impact of oil type on nanoemulsion formation and Ostwald Ripening stability. Langmuir 24, 12758–12765 (2008)
Damge, C., Vranckx, H., Balschmidt, P., Couvreur, P.: Poly(alkyl cyanoacrylate) nanospheres for oral administration of insulin. J. Pharm. Sci. 86, 1403–1409 (1997)
d’Angelo, I., Parajó, Y., Horváth, A., Kéri, G., La Rotonda, M.I., Alonso, M.J.: Improved delivery of angiogenesis inhibitors from PLGA: poloxamer blend micro- and nanoparticles. J. Microencapsul. 27, 57–66 (2010)
Ciriminna, R., Sciortino, M., Alonzo, G., Schrijver, A.D., Pagliaro, M.: From molecules to systems: Sol − Gel microencapsulation in silica-based materials. Chem. Rev. 111, 765–789 (2010)
Gouin, S.: Microencapsulation: industrial appraisal of existing technologies and trends. Trends Food Sci. Technol. 15, 330–347 (2004)
Kongsombut, B., Tsutsumi, A., Suankaew, N., Charinpanitkul, T.: Encapsulation of SiO2 and TiO2 fine powders with poly(DL-lactic-co-glycolic acid) by rapid expansion of supercritical CO2 incorporated with ethanol cosolvent. Ind. Eng. Chem. Res. 48, 11230–11235 (2009)
Peltonen, L., Valo, H., Kolakovic, R., Laaksonen, T., Hirvonen, J.: Electrospraying, spray drying and related techniques for production and formulation of drug nanoparticles. Expert Opin. Drug Deliv. 7, 705–719 (2010)
Javadzadeh, Y., Ahadi, F., Davaran, S., Mohammadi, G., Sabzevari, A., Adibkia, K.: Preparation and physicochemical characterization of naproxen-PLGA nanoparticles. Colloids Surf B Biointerfaces 81, 498–502 (2010)
Mura, P., Maestrelli, F., Cecchi, M., Bragagni, M., Almeida, A.: Development of a new delivery system consisting in ‘drug–in cyclodextrin–in PLGA nanoparticles’. J. Microencapsul. 27, 479–486 (2010)
Jaworek, A., Sobczyk, A.T.: Electrospraying route to nanotechnology: an overview. J. Electrostat. 66, 197–219 (2008)
Bonacucina, G., Cespi, M., Misici-Falzi, M., Palmieri, G.F.: Colloidal soft matter as drug delivery system. J. Pharm. Sci. 98, 1–42 (2009)
Chiu, Y.T., Chiu, C.P., Chien, J.T., Ho, G.H., Yang, J., Chen, B.H.: Encapsulation of lycopene extract from tomato pulp waste with gelatin and poly(γ-glutamic acid) as carrier. J. Agric. Food Chem. 55, 5123–5130 (2007)
Teixeira, Z., Zanchetta, B., Melo, B.A.G., Oliveira, L.L., Santana, M.H.A., Paredes-Gamero, E.J., Justo, G.Z., Nader, H.B., Guterres, S.S., Durán, N.: Retinyl palmitate flexible polymeric nanocapsules: characterization and permeation studies. Colloids Surf. B 81, 374–380 (2010)
Fondell, A., Edwards, K., Ickenstein, L., Sjöberg, S., Carlsson, J., Gedda, L.: Nuclisome: a novel concept for radionuclide therapy using targeting liposomes. Eur. J. Nucl. Med. Mol. Imaging 37, 114–123 (2010)
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Cano-Sarabia, M., Maspoch, D. (2012). Nanoencapsulation. In: Bhushan, B. (eds) Encyclopedia of Nanotechnology. Springer, Dordrecht. https://doi.org/10.1007/978-90-481-9751-4_50
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DOI: https://doi.org/10.1007/978-90-481-9751-4_50
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