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Adaptive Mechanisms of Extreme Alkaliphiles

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Extremophiles Handbook

Prologue

“Most engineers accept the ‘no free lunch’ principle, which states that any mechanism that increases robustness in one setting (i.e., to one type of perturbation, or with respect to one type of output) always compromises it in another” (Lander et 7al. 2009).

Introduction

Extreme alkaliphiles, like extremophiles in general, possess numerous structural, metabolic, physiological, and bioenergetic adaptations that enable them to function well under their particular “extreme” condition or, in the case of poly-extremophiles, under several extreme conditions at once (see also Chaps. 2.1 Introduction and History of Alkaliphiles, 2.4 Anaerobic Alkaliphiles and Alkaliphilic Poly-Extremophiles). If they are facultative extremophiles, many of the adaptations are present even under non-extreme growth conditions. That is, the adaptations to the extreme condition are “hard-wired” although their expression may increase further when the bacteria confront the extreme condition(s). The...

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Acknowledgments

Work conducted in the authors’ laboratories was supported by research grant GM28454 and the Systems Biology Center-NY grant P50-GM071558 from the National Institute of General Medical Sciences (T.A.K) and a grant from the 21st Century Center of Excellence program of the Ministry of Education, Culture, Sports, Science and Technology of Japan (M.I.).

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Krulwich, T.A., Liu, J., Morino, M., Fujisawa, M., Ito, M., Hicks, D.B. (2011). Adaptive Mechanisms of Extreme Alkaliphiles. In: Horikoshi, K. (eds) Extremophiles Handbook. Springer, Tokyo. https://doi.org/10.1007/978-4-431-53898-1_7

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