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Spezielle labortechnische Reaktoren: Hochdurchsatz-Reaktionstechnik

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Handbuch Chemische Reaktoren

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Zusammenfassung

In diesem Kapitel des Handbuchs Chemischer Reaktoren werden Ansätze zur Parallelisierung von Reaktoren mit dem Ziel der Erhöhung der Effizienz der Testverfahren, Reduktion des zeitlichen und finanziellen Aufwandes für die Testung, die Erhöhung der Reproduzierbarkeit der Ergebnisse und Wissensgenerierung beschrieben. Wie jedes experimentelle Vorgehen bedarf auch die Hochdurchsatz-Experimentation einer sehr sorgfältigen Planung der Versuche im Sinne eines Design of Experiment (DoE). Im Hochdurchsatz-Workflow werden anschließend die Phasen Primär- und Sekundärscreening solange durchlaufen, bis ein entsprechendes Entwicklungsziel erreicht worden ist. Parallelisiert werden können praktisch alle konventionellen Reaktortypen. Oberster Grundsatz bei der Planung und Entwicklung von Multireaktorsystemen ist ein völlig gleichartiges Verhalten aller Reaktoren des Parallelsystems, damit eine Vergleichbarkeit der Ergebnisse gegeben ist. Im Stadium der Realisierung eines Parallelisierungskonzeptes muss daher das Reaktorsystem immer gegen konventionelle Anlagen validiert werden. Vorgestellt werden Beispiele für Parallelreaktorkonzepte aus den Bereichen der mikrostrukturierten Hochdurchsatzreaktoren, der parallelen Strömungsrohrreaktoren, der parallelen Satzreaktoren und der photochemischen Parallelreaktoren.

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  1. Chemische Technologie, Technische Universität Chemnitz, Chemnitz, Deutschland

    Klaus Stöwe

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    Wladimir Reschetilowski

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Stöwe, K. (2018). Spezielle labortechnische Reaktoren: Hochdurchsatz-Reaktionstechnik. In: Reschetilowski, W. (eds) Handbuch Chemische Reaktoren. Springer Reference Naturwissenschaften . Springer Spektrum, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-56444-8_45-1

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