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Melanotische Flecke und melanozytäre Nävi

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Braun-Falco's Dermatologie, Venerologie und Allergologie

Part of the book series: Springer Reference Medizin ((SRM))

Zusammenfassung

Melanotische Flecke sind durch eine umschriebene Vermehrung von Melaninpigment charakterisiert, die Anzahl der epidermalen Melanozyten ist aber weitgehend normal oder nur gering vermehrt. Aufgrund der klinischen Ähnlichkeit sowie der Differenzialdiagnose zu und der häufigen Überlappung mit den melanozytären Nävi werden beide gemeinsam besprochen. Melanozytäre Nävi sind gutartige, umschriebene Proliferationen von Melanozyten in der Haut. Die Frage, ob es sich bei den melanozytären Nävi um genetisch determinierte Fehlbildungen (Hamartome) oder um benigne Tumoren der Melanozyten handelt, ist nicht einheitlich zu beantworten. So ist bei einem großen kongenitalen melanozytären Nävus eher von einem Hamartom auszugehen, während ein unter UV-Strahlung erworbener, sich in der Pubertät manifestierender melanozytärer Nävus eher im Sinne einer benignen Neoplasie der Melanozyten interpretiert werden kann. Im klinischen Alltag sind die benignen Pigmenttumoren vor allem wegen der Abgrenzung zum Melanom bedeutsam.

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Authors and Affiliations

  1. Klinik für Dermatologie, Venerologie und Allergologie, Helios Klinikum Hildesheim GmbH, Senator-Braun-Allee 33, 31135, Hildesheim, Deutschland

    Michael Tronnier

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  1. Michael Tronnier
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Correspondence to Michael Tronnier .

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Editors and Affiliations

  1. Dermatologie und Allergologie, Universitätsklinikum München Klinik und Poliklinik für, München, Bayern, Germany

    Gerd Plewig

  2. Dermatologie und Allergologie, Universitätsklinikum München Klinik und Poliklinik für, München, Bayern, Germany

    Thomas Ruzicka

  3. J.W.Goethe-Universität, Klinik für Dermatologie, Venerologie und Allergologie, Frankfurt, Hessen, Germany

    Roland Kaufmann

  4. Univ.Klinikum Marburg Klinik für Dermatologie und Allergologie, Marburg, Germany

    Michael Hertl

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  1. Direktor der Klinik für Dermatologie, Venerologie und Allergologie, Klinikum der J.W.Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Germany

    Roland Kaufmann

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Tronnier, M. (2016). Melanotische Flecke und melanozytäre Nävi. In: Plewig, G., Ruzicka, T., Kaufmann, R., Hertl, M. (eds) Braun-Falco's Dermatologie, Venerologie und Allergologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49546-9_104-1

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  • DOI: https://doi.org/10.1007/978-3-662-49546-9_104-1

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