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Akute myeloische Leukämie beim alten und geriatrischen Patienten

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Book cover Geriatrische Onkologie

Part of the book series: Springer Reference Medizin ((SRM))

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Zusammenfassung

Die akute myeloische Leukämie (AML) ist häufigste akute Leukämie im Erwachsenenalter, wobei mehr als die Hälfte der Patienten zum Zeitpunkt der Diagnosestellung älter als 65 Jahre alt sind. Zu Beginn der Behandlung eines älteren AML-Patienten ist die Auswahl einer geeigneten Primärtherapie von entscheidender Bedeutung. Hierbei müssen neben dem Wunsch des Patienten auch patientenbezogene sowie krankheitsspezifische Faktoren berücksichtigt werden. Für die individuelle Prognoseabschätzung steht heute eine Vielzahl von Scores zur Verfügung, die für die Einschätzung des Patienten im Sinne eines geriatrischen Assessments sowie für die Risikobeurteilung der vorliegenden AML-Erkrankung Anwendung finden. Auch wenn die optimale Erstlinientherapie für ältere Patienten mit einer AML weiterhin unklar ist, profitieren prinzipiell auch ältere Patienten von einer intensiven Therapie, sofern sie sich hierfür eignen. Alternativ stehen nicht-intensive und rein supportive Therapieoptionen zur Verfügung.

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Authors and Affiliations

  1. Medizinische Klinik 3, Klinikum Leverkusen, Am Gesundheitspark 11, 51375, Leverkusen, Deutschland

    Utz Krug

  2. III. Medizinische Klinik, Universitätsmedizin Mannheim, Theodor-Kutzer-Ufer 1-3, 68167, Mannheim, Deutschland

    Eva Lengfelder

  3. Center for Cell and Gene Therapy, Baylor College of Medicine, 1102 Bates Avenue, Houston, Texas, USA

    Tim Sauer

Authors
  1. Utz Krug
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  2. Eva Lengfelder
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  3. Tim Sauer
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Correspondence to Utz Krug .

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Editors and Affiliations

  1. II. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany

    Matthias Ebert

  2. II. Medizinische Klinik, Universitätsmedizin Mannheim, Mannheim, Germany

    Nicolai Härtel

  3. Klinik für Innere Medizin II, Universitätsklinikum Jena, Jena, Thüringen, Germany

    Ulrich Wedding

Section Editor information

  1. Abteilung für Palliativmedizin, Universitätsklinikum Jena, Klinik für Innere Medizin II, Erlanger Allee 101, 07747, Jena, Deutschland

    Ulrich Wedding

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Krug, U., Lengfelder, E., Sauer, T. (2017). Akute myeloische Leukämie beim alten und geriatrischen Patienten. In: Ebert, M., Härtel, N., Wedding, U. (eds) Geriatrische Onkologie. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-49083-9_16-1

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  • DOI: https://doi.org/10.1007/978-3-662-49083-9_16-1

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-49083-9

  • Online ISBN: 978-3-662-49083-9

  • eBook Packages: Springer Referenz Medizin

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