This term describes the severe decrease of T-cells in cases, when vertebrates including humans are infected by several viruses or by some protozoan parasites (e.g., Leishmania species, Plasmodium species, and Toxoplasma gondii).
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Further Reading
Gigley J et al (2012) T-cell exhaustion in protozoan diseases. Trends Parasitol 28:377–384
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Mehlhorn, H. (2016). T Cell Exhaustion. In: Mehlhorn, H. (eds) Encyclopedia of Parasitology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-43978-4_4369
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