Advertisement

Gelenk- und Muskelschmerzen

  • Michael Bernateck
  • J. G. Kuipers
  • Henning Zeidler
  • Lars Köhler
  • Jan L. Hülsemann
  • Sebastian Schnarr
Living reference work entry

Zusammenfassung

Arthrosen sind die häufigsten Gelenkerkrankungen weltweit und führen zu einer Verschlechterung der Gelenkfunktion sowie zu akuten, intermittierenden oder chronischen Gelenkschmerzen.

Literatur

  1. Altman RD, Hochberg MC, Moskowitcz RW, Schnitzer TJ (2000) Recommendations for the medical management of Osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines. Arthritis Rheum 43: 1905–1915CrossRefGoogle Scholar
  2. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines (2000) Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. Arthritis Rheum 43: 1905–1915CrossRefGoogle Scholar
  3. Baer PA, Tenebaum J, Fam AG, Little H (1986) Coexistent septic arthritis and crystal arthritis. Report of four cases and literature review. J Rheumatol 13: 604–607PubMedGoogle Scholar
  4. Bandolier Knowledge Library 2002: Paracetamol (acetaminophen) for osteoarthritis. www.jr2.ox.ac.uk/bandolier/booth/Arthritis/paraoa.html. Zugegriffen im März 2012.
  5. Bandolier Monthly Journal 2000: Use of paracetamol in rheumatic disease. www.jr2.ox.ac.uk/bandolier/band76/b76-5.html. Zugegriffen im März 2012.
  6. Bandolier Pain Site 2004: NSAIDs for treating Osteoarthritis. www.jr2.ox.ac.uk/bandolier/booth/painpag/Chronrev/OARA/OANSAID.html. Zugegriffen im Mðrz 2012.
  7. Becker MA, Schumacher HR Jr, Wortmann RL, MacDonald PA, Eustace D, Palo WA, Streit J, Joseph-Ridge N (2005) Febuxostat compared with allopurinol in patients with hyperuricemia and gout. N Engl J Med 853: 2450–2461CrossRefGoogle Scholar
  8. Bellamy N, Campbell J, Robinson V, Gee T, Bourne R, Wells G (2005) Intraarticular corticosteroid for treatment of osteoarthritis of the knee. Cochrane Database Syst Rev 18:367–374Google Scholar
  9. Berenbaum F (2008) New horizons and perspectives in the treatment of osteoarthritis. Arthritis Res Ther 10:441–449CrossRefGoogle Scholar
  10. Bolland MJ, Grey AB, Reid IR (2010) Effect of Osteoposis treatment on mortality: a meta-analysis. J Clin Endocrinol Metab 95: 1174–1185CrossRefPubMedGoogle Scholar
  11. Brosseau L, Yonge KA, Robinson V, Marchand S, Judd M, Wells G, Tugwell P (2004) Thermotherapy for treatment of osteoarthritis (Cochrane Review). The Cochrane Library, Issue 1, 2004. John Wiley, Chichester, UKGoogle Scholar
  12. Brown FL, Bodison S, Dixon J, et al. (1986) Comparison of diflunisal and acetaminophen with codeine in the treatment of initial or recurrent acute low back strain. Clin Ther 9 (SupplC): 52–58Google Scholar
  13. Burmester G, Lanas A, Biasucci L, et al. (2011) The appropriate use of non-steroidal anti-inflammatory drugs in rheumatic disease: opinions of a multidisciplinary European expert panel. Ann Rheum Dis 70: 818–822PubMedCentralCrossRefPubMedGoogle Scholar
  14. Buttgereit F, Burmester G, Bijlsma JW (2005) Which dose regimen for glucocorticoid pulse therapy in patients with severe refractory RA. Ann Rheum Dis 64: 170–172Google Scholar
  15. Buttgereit F, Mehta D, Kirwan J, et al. (2012) Low-dose prednisone chronotherapy for rheumatoid arthritis: a randomized clinical trial (CAPRA-2). Ann Rheum Dis, doi:10.1136/annrheumdis-2011-201067. Zugegriffen im März 2012.Google Scholar
  16. Cannon CP, Curtis SP, FitzGerald GA, Krum H, Bolognese JA, Bombardier C, Weinblatt ME, van der Heijde D, Laine L (2006) Cardiovascular outcomes with etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Long-term (MEDAL) programme: a randomised comparison. Lancet 18(9549):1771–1781CrossRefGoogle Scholar
  17. Chan FK, Lanas A, Scheiman J, et al. (2010) Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomized trial. Lancet 376(9736): 173–179CrossRefPubMedGoogle Scholar
  18. Cooper C, Cawley MID (1986) Bacterial arthritis in the elderly. Gerontology 32: 222–227CrossRefPubMedGoogle Scholar
  19. Creamer P (1999) Intra-articular corticosteroid treatment in osteoarthritis. Curr Opin Rheumatol. 11: 417–421CrossRefPubMedGoogle Scholar
  20. Dachverband Osteologie in Deutschland (DVO): Evidenz-basierte Empfehlungen zur Prävention und Therapie der Osteoporose. www.dv-osteologie.org. Zugegriffen im März 2012.
  21. Dagfinrud H, Kvien TK, Hagen KB (2008). Physiotherapy interventions for ankylosing spondylitis. Cochrane Database Syst Rev. CD002822Google Scholar
  22. Derendorf H, Mollmann H, Gruner A, Haack D, Gyselby G (1986) Pharmacokinetics and pharmacodynamics of glucocorticoid suspensions after intra-articular administration. Clin Pharmacol Ther 39: 313–317CrossRefPubMedGoogle Scholar
  23. Derry S, Moore RA, Rabbie R (2012) Topical NSAIDs for chronic musculoskeletal pain in adults. Cochrane Database Syst Rev 2012(9): CD007400. doi: 10.1002/14651858.CD007400.pub2. Zugegriffen im März 2012.Google Scholar
  24. Dougados M, et al. (2010) A randomised, multicentre, double-blind, placebo-controlled trial of etanercept in adults with refractory heel enthesitis in spondyloarthritis: the HEEL trial. Ann Rheum Dis 69: 1430–1435CrossRefPubMedGoogle Scholar
  25. Dt. Ges. f. Rheumatologie: Dokumente. www.dgrh.de/dgrhcontent/m1/k6/Artikel1017.aspxx. Zugegriffen im März 2012.
  26. Echtermeyer F, Bertrand J, Dreier R, Meinecke I, et al. (2009) Syndecan-4 regulates ADAMTS-5 activation and cartilage breakdown osteoarthritis. Nat Med 15:1072–1076CrossRefPubMedGoogle Scholar
  27. Fransen M, McConnell S, Bell M (2004) Exercise for osteoarthritis of the hip or knee (Cochrane Review). The Cochrane Library, Issue 1, 2004. John Wiley, Chichester, UKGoogle Scholar
  28. Fransen M, McConnell S, Hernandez-Molina G, Reichenbach S (2010) Does land-based exercise reduce pain and disability associtated with hip osteoarthritis? A meta-analysis of randomized controlled trials. Osteoarthritis Cartilage 18:613–620CrossRefPubMedGoogle Scholar
  29. García-Arias M, Balsa A, Mola EM (2011) Septic arthritis. Best Pract Res Clin Rheumatol 25:407–421CrossRefPubMedGoogle Scholar
  30. Genth E, Gromnica-Ihle E, Häntzschel H, Kalden JR, Keitel W, Mathies H, Raspe HH, Schneider M, Warnatz H, Zacher J (2000) Deutsche Gesellschaft für Rheumatologie, Kommission für Qualitätssicherung: Qualitätssicherung in der Rheumatologie. Steinkopff, Darmstadt. www.rheumanet.org/qs_dgrh/default.htm. Zugegriffen im März 2012.
  31. Gotzsche PC, Johansen HK (1998) Meta-analysis of short-term low dose prednisolone versus placebo and non-steroidal anti-inflammatory drugs in rheumatoid arthritis. BMJ 316: 811–818PubMedCentralCrossRefPubMedGoogle Scholar
  32. Gresser U (2003) Diagnose und Therapie der Gicht. Dtsch Ärztebl 44: 1462–1469Google Scholar
  33. Hanauer SB, Present DH (2003) The state of the art in the management of inflammatory bowel disease. Rev Gastroenterol Disord 3: 81–92PubMedGoogle Scholar
  34. Hochberg MC, Altman RD, April KT, Benkhalti M, Guyatt G, McGowan J, Towheed T, Welch V, Wells G, Tugwell P; American College of Rheumatology (2012) American College of Rheumatology 2012 recommendations for the use of nonpharmacologic and pharmacologic therapies in osteoarthritis of the hand, hip, and knee. Arthritis Care Res 64: 465–474CrossRefGoogle Scholar
  35. Hoy SM (2012) Tapentadol extended release: in adults with chronic pain. Drugs 72: 375–393CrossRefPubMedGoogle Scholar
  36. Hunter JA, Blyth TH (1999) A risk-benefit assessment of intra-articular corticosteroids in rheumatic disorders. Drug Saf 21: 353–365CrossRefPubMedGoogle Scholar
  37. Jerosch J (2008) Eitrige Arthritis. In: Zeidler H, Zacher J, Hiepe F (Hrsg) Interdisziplinäre klinische Rheumatologie. Springer, Berlin Heidelberg New York, S 419–432Google Scholar
  38. Jordan KM, Cameron JS, Snaith M, Zhang W, Doherty M, Seckl J, Hingorani A, Jaques R, Nuki G (2007) British Society for Rheumatology and British Health Professionals in Rheumatology Standards, Guidelines and Audit Working Group (SGAWG): British Society for Rheumatology and British Health Professionals in Rheumatology guideline for the management of gout. Rheumatology 46: 1372–1374CrossRefPubMedGoogle Scholar
  39. Kannus P, Parkkari J, Niemi S, Pasanen M, Palvanen M, Järvinen M, Vuori I (2000) Prevention of hip fracture in elderly people wirh the use of a hip protector. N Engl J Med 343: 1506–1513CrossRefPubMedGoogle Scholar
  40. Karst M, Jasper S, Bernateck M, Stephan M (2012) Clinical diagnostics and therapy of chronic pain syndromes. Psychother Psychosom Med Psychol 62:320–330CrossRefPubMedGoogle Scholar
  41. Kirwan JR (1995) The effect of glucocorticoids on joint destruction in rheumatoid arthritis. The Arthritis and Rheumatism Council Low-Dose Glucocorticoid Study Group. N Engl J Med 333: 142–146CrossRefPubMedGoogle Scholar
  42. Köhler L, Zeidler H, Kuipers JG (2000) Aktueller Stand der medikamentösen Therapie der Spondarthritiden und reaktiven Arthritiden. Akt Rheumatol 25: 30–37CrossRefGoogle Scholar
  43. Kriegsmann J, Hopf T, Jacobs D, Arens N, Krenn V, Schmitt-Wiedhoff R, Kriegsmann M, Heisel C, Biehl C, Thabe H, Schmitz RPH, Lehmann M, Otto M (2009) Molekularpathologische Diagnostik von Gelenkinfektionen. Orthopäde 38: 531–538CrossRefPubMedGoogle Scholar
  44. Laine L, Curtis SP, Cryer B, Kaur A, Cannon CP (2007) Assessment of upper gastrointestinal safety of etoricoxib and diclofenac in patients with osteoarthritis and rheumatoid arthritis in the Multinational Etoricoxib and Diclofenac Arthritis Longterm (MEDAL) programme: a randomised comparison. Lancet 10(9560): 465–473CrossRefGoogle Scholar
  45. Lindsay R, Silverman SL, Cooper C, et al. (2001) Risk of new vertebral fracture in the year following a fracture. JAMA 285: 320–323CrossRefPubMedGoogle Scholar
  46. Longo UG, Loppini M, Denaro L, et al. (2012) Conservative management of patients with an osteoporotic vertebral fracture. J Bone Joint Surg Br 94-B: 152–157CrossRefGoogle Scholar
  47. Malmros B, Mortensen L, Jensen MB, Charles P (1998) Positive effect of physiotherapy on chronic pain and performance in osteoporosis. Osteoporosis Int 8: 215–221CrossRefGoogle Scholar
  48. Montagu A, Speirs A, Baldock J, et al. (2012) A review of vertebroplasty for osteoporotic and malignant vertebral compression fractures. Age Ageing 41: 450–455CrossRefPubMedGoogle Scholar
  49. Moore RA, Tramèr MR, Carroll D, Wiffen PJ, McQuay HJ (1998) Quantitive systematic review of topically applied non-steroidal anti-inflammatory drugs. BMJ 316: 333–338PubMedCentralCrossRefPubMedGoogle Scholar
  50. Müller-Ladner U, Panzner I, Kriegsmann J, Lange U, Tausche AK (2011) Gicht – die „vergessene“ Erkrankung trotz vieler therapeutischer Optionen. Dtsch Med Wochenschr 136: 1660–1664CrossRefPubMedGoogle Scholar
  51. Nüesch E, Rutjes AW, Husni E, Welch V, Jüni P (2009) Cochrane Database Syst Rev 7: 344–353Google Scholar
  52. Papaioannou A, Watts NB, Kendler DL, Yuen CK, Adachi JD, Ferko N (2002) Diagnosis and management of vertebral fractures in elderly adults. Am J Med 113: 220–228CrossRefPubMedGoogle Scholar
  53. Petrella RJ, Petrella M (2006) A prospective randomized, double-blind, placebo-controlled study to evaluate the efficacy of intraarticular hyaluronic acid for osteoarthritis of the knee. J Rheumatol 33: 951–956PubMedGoogle Scholar
  54. Pfeifer M, Dreher R, Minne HW (2001) Nicht-medikamentöse Maßnahmen bei Osteoporose. Akt Rheumatol 26: 219–226CrossRefGoogle Scholar
  55. Pfeiffer M, Begerow B, Minne HW (2004) Effect of a new spinal orthosis on posture, trunk strength, and qualitiy of life in women with postmenoposal osteoporosis: a randomized trial. Am J Phys Med Rehabil 83: 177–186CrossRefGoogle Scholar
  56. Piper JM, Ray WA, Daughterty JR, Griffin MR (1991) Corticosteroid use and peptic ulcer disease: role of nonsteroidal anti-inflammatory drugs. Ann Intern Med 114: 735–740CrossRefPubMedGoogle Scholar
  57. Poddubnyy D, et al. (2012) Effect of non-steroidal anti-inflammatory drugs on radiographic spinal progression in patients with axial spondyloarthritis: results from the German Spondyloarthritis Inception Cohort. Ann Rheum Dis 71: 1616–1622CrossRefPubMedGoogle Scholar
  58. Rau R, Wassenberg S, Zeidler H; LDPT-Study Group (2000) Low dose prednisolone therapy (LDPT) retards radiographically detectable destruction in early rheumatoid arthritis - preliminary results of a multicenter, randomized, parallel, double blind study. Z Rheumatol 59 (Suppl 2): II/90–96Google Scholar
  59. Reginster JY, Badurski J, Bellamy N, et al. (2012) Efficacy and safety of strontium ranelate in the treatment of knee osteoarthritis: results of a double blind, randomized placebo-controlled trial. Ann Rheum Dis 8: 693Google Scholar
  60. Ritchlin CT, et al. (2009) Group for Research ans Assessment of Psoriasis and Psoriatic Arthtitis (GRAPPA) Treatment recommendations for psoriatic arthritis. Ann Rheum Dis 68: 1387–1394PubMedCentralCrossRefPubMedGoogle Scholar
  61. Rudwaleit M, et al. (2009) The development of assessment of spondyloarthritis international society classification criteria for axial spondyloarthritis (part II): validation and final selection. Ann Rheum Dis 68: 777–783CrossRefPubMedGoogle Scholar
  62. Rudwaleit M, et al. (2011) The assessment of spondyloarthritis international society classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general. Ann Rheum Dis 70: 25–31CrossRefPubMedGoogle Scholar
  63. Schlesinger N, Schumacher R, Ottawa Methods Group (2003) Gout. In: Evidence-based rheumatology. BMJ books, London, 65–95CrossRefGoogle Scholar
  64. Sieper J, et al. (2012) Efficacy and safety of adalimumab in patients with non-radiographic axial spondyloarthritis: results of a randomised placebo-controlled trial (ABILITY-1). Ann Rheum Dis Jul 7. Epub ahead of printGoogle Scholar
  65. Sinaki M, Itoi E, Wahner HW, et al. (2002) Stronger back muscles reduce the incidence of vertebral fractures: a prospective 10 year follow-up of postmenopausal women. Bone 30: 836–841CrossRefPubMedGoogle Scholar
  66. Smith RL, Schurmann DJ, Kajiyama G, Sarossy J (1990) Effect of NSAID and antibiotic treatment in a rabbit model of Staphylococcus infectious arthritis. Trans Orthop Res Soc 15: 296Google Scholar
  67. Tausche AK, Jansen TL, Schröder HE, Bornstein SR, Aringer M, Müller-Ladner U (2009) Gicht – aktuelle Aspekte in Diagnostik und Therapie. Dtsch Ärzteblatt 106: 549–555Google Scholar
  68. Terkeltaub RA (2003) Clinical practice. Gout. NEJM 349: 1647–1655CrossRefPubMedGoogle Scholar
  69. Towheed TE, Judd MJ, Hochberg MC, Wells G (2004a) Acetaminophen for osteoarthritis (Cochrane Review). The Cochrane Library, Issue 1, 2004. John Wiley, Chichester, UKGoogle Scholar
  70. Towheed T, Shea B, Wells G, Hochberg M (2004b) Analgesia and non-aspirin, non-steroidal anti-inflammatory drugs for osteoarthritis of the hip (Cochrane Review). The Cochrane Library, Issue 1, 2004. John Wiley, Chichester, UKGoogle Scholar
  71. Van Baar ME, Decker J, Ostendoorp RA, Bijl D, Voorn TB, Lemmens JA, Bijlsma JW (1998) The effectiveness of exercise therapy in patients with osteoarthritis of the hip or knee: a randomized clinical trial. J Rheumatol 25: 2432–2439PubMedGoogle Scholar
  72. Van Tulder MW, Scholten RJ, Koes BW, Deyo RA (2000) Non-steroidal anti-inflammatory drugs for low back pain. Cochrane Database Syst Rev 2000; (2):CD000396.Google Scholar
  73. Vincenti F (1982) Septic arthritis following renal transplantation. Nephron 30: 253-256CrossRefPubMedGoogle Scholar
  74. Wassenberg S, Rau R, Steinfeld P, Zeidler H (2005) Very low-dose prednisolone in early rheumatoid arthritis retards radiographic progression over two years: a multicenter, double-blind, placebo-controlled trial. Arthritis Rheum 52: 3371–3380CrossRefPubMedGoogle Scholar
  75. Watson MC, Brookes ST, Kirwan JR, Faulkner A (2004) Non-aspirin, non-steroidal anti-inflammatory drugs for treating osteoarthritis of the knee (Cochrane Review). The Cochrane Library, Issue 1, 2004. John Wiley, Chichester, UKGoogle Scholar
  76. Weinstein JN (2009) Balancing science and informed choice in decisions about vertebroplasty. NEJM 361: 619–621CrossRefPubMedGoogle Scholar
  77. Winthrop KL, Chang E, Yamashita S, Iademarco MF, LoBue PA (2009). Nontuberculous mycobacteria infections and anti-tumor necrosis factor-alpha therapy. Emerg Infect Dis 15: 1556–1561PubMedCentralCrossRefPubMedGoogle Scholar
  78. Witt C, Brinkhaus B, Jena S, Linde K, Streng A, Wagenpfeil S, Hummelsberger J, Walther HU, Melchart D, Willich SN (2005) Acupuncture in patients with osteoarthritis of the knee: a randomised trial. Lancet 366(9480): 136–143CrossRefPubMedGoogle Scholar
  79. Wolff I, van Croonenborg J, Kemper HCG, et al. (1999) The effect of exercise training programs on bone mass: a meta-analysis of published controlled trials in pre- and postmenopausal women. Osteoporosis Int 9: 1–12CrossRefGoogle Scholar
  80. Zeidler H, Amor B (2011) The Assessment in Spondyloarthritis International Society (ASAS) classification criteria for peripheral spondyloarthritis and for spondyloarthritis in general: the spondyloarthritis concept in progress. Ann Rheum Dis 70: 1–3CrossRefPubMedGoogle Scholar
  81. Zhang W, Doherty M, Bardin T, Pascual E, Barskova V, Conaghan P, Gerster J, Jacobs J, Leeb B, Lioté F, McCarthy G, Netter P, Nuki G, Perez-Ruiz F, Pignone A, Pimentão J, Punzi L, Roddy E, Uhlig T, Zimmermann-Gòrska I (2006a) EULAR Standing Committee for International Clinical Studies Including Therapeutics. EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 65: 1312–1324PubMedCentralCrossRefPubMedGoogle Scholar
  82. Zhang W, Doherty M, Pascual E, Bardin T, Barskova V, Conaghan P, Gerster J, Jacobs J, Leeb B, Liotè F, McCarthy G, Netter P, Nuki G, Perez-Riuz F, Pignone A, Pimantao J, Punzi L, Roddy E, Uhlig, T, Zimmermann-Gòrska I (2006b) EULAR Standing Committee for International Clinical Studies Including Therapeutics. EULAR evidence based recommendations for gout. Part I: Diagnosis. Report of a task force of the Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 65: 1301–1311PubMedCentralCrossRefPubMedGoogle Scholar
  83. Zulian F, Martini G, Gobber D, Agosto C, Gigante C, Zacchello F (2003) Comparison of intra-articular triamcinolone hexacetonide and triamcinolone acetonide in oligoarticular juvenile idiopathic arthritis. J Rheumatol 42: 1254–1259CrossRefGoogle Scholar

Leitlinien

  1. Arbeitsgemeinschaft der Wissenschaftlichen Medizinischen Fachgesellschaften (AWMF) (2004) Hygiene in Klinik und Praxis, 3. Aufl. mhp-Verlag, Wiesbaden, S 51ff. www.uni-duesseldorf.de/AWMF/: AWMF-Leitlinien-Register Nr. 029/006. Zugegriffen im März 2012.
  2. Braun J, et al (2011) 2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis. Ann Rheum Dis 70: 896–904PubMedCentralCrossRefPubMedGoogle Scholar
  3. Dachverband Osteologie (2011) DVO Guideline 2009 for Prevention, Diagnosis and Therapy of Osteoporosis in Adults. Osteologie 20: 55–74Google Scholar
  4. Dt. Ges. f. Orthopädie und Traumatologie u. Berufsverb. d. Ärzte f. Orthopädie (Hrsg) (2002) Intraartikuläre Punktionen und Injektionen. Leitlinien der Orthopädie, 2. Aufl. Dt. Ärzte-Verlag, KölnGoogle Scholar
  5. Gossec L, et al. (2012) European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies. Ann Rheum Dis 71: 4–12CrossRefPubMedGoogle Scholar
  6. Krüger K, Wollenhaupt J, Burmester GR, et al. (2012) S1-Leitlinie der DGRh zur sequenziellen medikamentösen Therapie der Rheumatoiden Arthritis. Z Rheumatol 71: 592–603CrossRefPubMedGoogle Scholar
  7. S2-Leitlinie „Bakterielle Gelenkinfektion“ der Deutschen Gesellschaft für Unfallchirurgie e.V. www.awmf.org/leitlinien/detail/ll/012-010.html. Zugegriffen im März 2012.

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Michael Bernateck
    • 1
  • J. G. Kuipers
    • 2
  • Henning Zeidler
    • 3
  • Lars Köhler
    • 4
  • Jan L. Hülsemann
    • 5
  • Sebastian Schnarr
    • 6
  1. 1.Klinik für Anästhesie und IntensivmedizinMedizinische Hochschule HannoverHannoverDeutschland
  2. 2.Klinik für internistische RheumatologieRotes Kreuz Krankenhaus Bremen gGmbHBremenDeutschland
  3. 3.Universitätsmedizin Göttingen, SchmerzklinikHannoverDeutschland
  4. 4.Rheumatologische FacharztpraxisHannoverDeutschland
  5. 5.Universitätsklinikum MagdeburgMagdeburgDeutschland
  6. 6.Rheumaklinik OstbayernBad FüssingDeutschland

Personalised recommendations