Encyclopedia of Immunotoxicology

2016 Edition
| Editors: Hans-Werner Vohr

Psoriasis

Reference work entry
DOI: https://doi.org/10.1007/978-3-642-54596-2_201235

Psoriasis vulgaris is a frequently occurring skin disease in fair-skinned individuals. Disease starts often in the second decade of life triggered by infections like angina or measles. Pathogenesis involves hyperproliferation of keratinocytes, and accelerated migration of keratinocytes from the basal to the horny layer in 4 days (normal 28 days). Symptoms are intense desquamation of the skin and itching.

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© Springer-Verlag Berlin Heidelberg 2016