Synonyms
Amphipathic molecules; Amphiphiles; Amphiphilic block copolymers; Amphiphilic polymers; Amphipols; Detergents; Emulsifiers; Hydrotropes; Lipids/phospholipids; Soaps; Surfactants
Amphiphilic molecules is a general term that describes any compound that contains two distinct covalently bonded components with different affinity for the solvent in the same molecule, in which one part possesses a high affinity for polar solvents (such as water), and another part has a strong affinity for nonpolar solvents, such as hydrocarbons, ethers, and esters. Surfactants, polymer amphiphiles, and some lipid molecules, containing both hydrophilic and hydrophobic components, are typical examples of amphiphilic molecules.
Low Molecular Weight Amphiphiles
Surfactants (surface active agents), more popularly known as soaps, are among the oldest known chemicals used by human. This type of molecules now play a crucial role in many areas such as cleaning products, food, cosmetics, pharmaceuticals, and...
This is a preview of subscription content, access via your institution.


References
Chevalier Y (2002) New surfactants: new chemical functions and molecular architectures. Curr Opin Colloid Interface Sci 7:3–11
Fuhrhop JH, Wang T (2004) Bolaamphiphiles. Chem Rev 104:2901–2937
Holmberg K, Jonsson B, Kronberg B, Lindman B (2002) Surfactants and polymers in aqueous solution, 2nd edn. Wiley, Chichester
Israelachvili JN, Mitchell J, Ninham BW (1976) Theory of self-assembly of hydrocarbons amphiphiles into micelles and bilayers. J Chem Soc Faraday Trans 72:1525–1568
Mai Y, Eisenberg A (2012) Self-assembly of block copolymers. Chem Soc Rev 41:5969–5985
Nagarajan R (2011) Amphiphilic surfactants and amphiphilic polymers: principles of molecular assembly. ACS Symp Ser 1070(1):1–22
Schacher FH, Rupar PA, Manners I (2012) Functional block copolymers: nanostructured materials with emerging applications. Angew Chem Int Ed 51:2–25
Schramm LL, Stasiuk EN, Marangoni DG (2003) Surfactants and their applications. Annu Rep Prog Chem Sect C Phys Chem 99:3–48
Wang Y, Grayson SM (2012) Approaches for the preparation of non-linear amphiphilic polymers and their applications to drug delivery. Adv Drug Deliv Rev 64:852–865
Zhang J, Li X, Li X (2012) Stimuli-triggered structural engineering of synthetic and biological polymeric assemblies. Prog Polym Sci 37:1130–1176
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2014 Springer-Verlag Berlin Heidelberg
About this entry
Cite this entry
Zhang, J. (2014). Amphiphilic Molecules. In: Drioli, E., Giorno, L. (eds) Encyclopedia of Membranes. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-40872-4_1789-1
Download citation
DOI: https://doi.org/10.1007/978-3-642-40872-4_1789-1
Received:
Accepted:
Published:
Publisher Name: Springer, Berlin, Heidelberg
Online ISBN: 978-3-642-40872-4
eBook Packages: Springer Reference Chemistry & Mat. ScienceReference Module Physical and Materials Science