Definition
A transcription factor regulating the CRF gene. Glucocorticoid receptors (GR) are stabilized in the cytosol by various chaperones before homodimerizing and translocating into the nucleus. Childhood abuse and polymorphisms in FKBP5, a chaperone for GR, are associated with posttraumatic stress disorder.
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© 2015 Springer-Verlag Berlin Heidelberg
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(2015). Glucocorticoid Receptor. In: Stolerman, I.P., Price, L.H. (eds) Encyclopedia of Psychopharmacology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-36172-2_200048
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DOI: https://doi.org/10.1007/978-3-642-36172-2_200048
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