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Definition
Rare multisystem disease that affects the cornea by causing stromal interstitial keratitis and the vestibuloauditory system by causing vertigo and deafness.
Clinical Presentation
Usually affect young adults. The majority of the patients report an upper respiratory tract infection few weeks before the onset of ocular or vestibuloauditory symptoms (Snow and Wackym 2009). The most common eye finding is a chronic bilateral interstitial keratitis; it begins with faint paralimbal (peripheral) subepithelial infiltrate of the cornea, and the patient may complain of irritation, photophobia, redness, and decreased vision. Later those lesions may progress centrally...
References
Kanski JJ, Bowling B (2011) Clinical ophthalmology: a systematic approach, 7th edn. Elsevier, Edinburgh, pp 193–194
Skuta GL et al. (2011–2012) Basic and clinical science course: section 8 external disease and cornea. AAO, San Francisco, CA, pp 209–210
Snow JB, Wackym PA (2009) Ballenger’s otorhinolaryngology head and neck surgery, 17th edn. PMPH, Shelton, CT, p 309
Yanoff M, Duker JS (2004) Ophthalmology, 2nd edn. St. Louis, MO, pp 459–460
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Alkharashi, M., Alkharashi, M. (2014). Cogan Syndrome. In: Schmidt-Erfurth, U., Kohnen, T. (eds) Encyclopedia of Ophthalmology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-35951-4_774-1
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DOI: https://doi.org/10.1007/978-3-642-35951-4_774-1
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Publisher Name: Springer, Berlin, Heidelberg
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