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Membrane Protein Function

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Encyclopedia of Biophysics


7-Transmembrane Domain Receptors


The varied functions performed by specific membrane proteins and peptides, including enzymatic reactions, membrane transport, cell communication, light harvesting, membrane disruption, and cell adhesion.


Membrane proteins account for approximately 30% of the proteins encoded by a typical genome (Wallin and von Heijne 1998). This abundance gives some indication of the diversity of function of this class of protein. Typically, they are involved in regulating the cell’s response to, and interaction with, the environment. Each of these processes is critical to correct cellular function, and the examples below serve to highlight the importance of this class of proteins (Smith 2010).


Receptors on the cell surface transduce signals from the external environment across the cellular membrane, leading to downstream responses. They detect a wide variety of stimuli and result in an equally diverse array of cellular...

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Correspondence to Anthony Watts .

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Goddard, A., Román Lara, M.M., Depping, P., Oates, J., Watts, A. (2020). Membrane Protein Function. In: Roberts, G., Watts, A. (eds) Encyclopedia of Biophysics. Springer, Berlin, Heidelberg.

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