Encyclopedia of Biophysics

Living Edition
| Editors: Gordon Roberts, Anthony Watts, European Biophysical Societies

Electron Microscopy of Motor Structure and Possible Mechanisms

  • Tohru Minamino
  • Takayuki Kato
  • Fumiaki Makino
  • Péter Horváth
  • Tomoko Miyata
  • Keiichi Namba
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-35943-9_196-1

Synonyms

Definition

Structural analyses of substructures of the bacterial flagellum by the complementary use of cryoelectron microscopy and X-ray crystallography provide structural and mechanical insights into the mechanisms of how they can exert their functions.

Introduction

The bacterial flagellum is supramolecular motility machinery consisting at least of three parts: the basal body, the hook, and the filament. Flagellar assembly begins with the basal body, followed by the hook, and finally the filament. Most flagellar proteins are translocated via a type III protein export apparatus into the central channel of the growing flagellar structure and assemble at the distal end of the structure with the help of a capping structure. Escherichia coli and Salmonella entericaare model organisms that have provided detailed insights into the structure, assembly, and function of the...

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References

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Copyright information

© European Biophysical Societies' Association (EBSA) 2018

Authors and Affiliations

  • Tohru Minamino
    • 1
  • Takayuki Kato
    • 1
  • Fumiaki Makino
    • 1
  • Péter Horváth
    • 1
  • Tomoko Miyata
    • 1
  • Keiichi Namba
    • 1
  1. 1.Graduate School of Frontier BiosciencesOsaka UniversityOsakaJapan

Section editors and affiliations

  • Judith P. Armitage
    • 1
  1. 1.OCISB, Department of BiochemistryUniversity of OxfordOxfordUK