The Family Bartonellaceae

  • Cristiane Divan Baldani
  • Huarrisson Azevedo Santos
  • Carlos Luiz Massard
Reference work entry


Bartonellaceae is a family within the order Rhizobiales in the sub-class of Alphaproteobacteria which contains only the genus Bartonella. They are fastidious, facultative intracellular, slow-growing, gram-negative, slightly curved bacilli that cause a wide range of diseases in humans and animals, some species being zoonotic. Clinical manifestations in humans include Carrión’s disease, trench fever, cat scratch disease, bacteremia with fever, bacillary angiomatosis and peliosis, endocarditis, and neuroretinitis. Colony morphology varies from clear to smooth white and rough tan. Several species embed in the agar. They are typically inert biochemically; the organisms are usually catalase and oxidase negative and aerobic, and they do not produce acid from carbohydrates. Some species are motile. The genus Bartonella, to date, contains 29 species and 3 subspecies. Most Bartonella species have successfully adapted to survival in specific domestic or wild mammals. Blood-sucking arthropod vectors are often involved. Clinical presentation generally depends on both the infecting Bartonella species and the immune status of the infected individual. Bartonella species are susceptible to many antibiotics in vitro; however, in vivo antibiotic susceptibilities do not correlate well for a number of antibiotics.


Type Strain Rabbit Blood Moist Atmosphere Bartonella Species gltA Gene 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



The support of CNPq, FAPERJ and Federal Rural University of Rio de Janeiro is greatly acknowledged. The authors wish to thank Dr. Rosangela Zacarias Machado (UNESP/FCAV/Brazil) for stimulating first studies on Bartonella spp., as well as the M.Sc. and Ph.D. students Aline Tonussi da Silva, Andresa Guimarães, and Juliana Macedo Raimundo for review of the text and Dr. Vera Lucia Divan Baldani (EMBRAPA/Agrobiologia) for suggestions in the topics phenotypic analyses and isolation procedures.


  1. Abbott RC, Chomel BB, Kasten RW, Floyd-Hawkins KA, Kikuchi Y, Kochler JE, Pedersen NC (1997) Experimental and natural infection with Bartonella henselae in cats. Comp Immunol Microbiol Infect Dis 20(1):41–57PubMedCrossRefGoogle Scholar
  2. Alexander B (1995) A review of bartonellosis in Ecuador and Colombia. Am J Trop Med Hyg 52(4):354–359PubMedGoogle Scholar
  3. Alsmark CM, Frank AC, Karlberg EO, Legault B, Ardell DH, Canback B, Eriksson AS, Naslund AK, Handley SA, Huvet M, La Scola B, Holmberg M, Andersson SGE (2004) The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae. Proc Natl Acad Sci U S A 101:9716–9721PubMedCentralPubMedCrossRefGoogle Scholar
  4. Anderson BE, Neuman MA (1997) Bartonella spp. as emerging human pathogens. Clin Microbiol Rev 10:203–219PubMedCentralPubMedGoogle Scholar
  5. Anderson B, Goldsmith C, Johnson A, Padmalayam I, Baumstark B (1994) Bacteriophage-like particle of Rochalimaea henselae. Mol Microbiol 13:67–73PubMedCrossRefGoogle Scholar
  6. Anderson B, Lu E, Jones D, Regnery R (1995) Characterization of a 17-kilodalton antigen of Bartonella henselae reactive with sera from patients with cat scratch disease. J Clin Microbiol 33(9):2358–2365PubMedCentralPubMedGoogle Scholar
  7. Angelakis E, Biswas S, Taylor C, Raoult D, Rolain JM (2008) Heterogeneity of susceptibility to fluoroquinolones in Bartonella isolates from Australia reveals a natural mutation ingyrA. J Antimicrob Chemother 61:1252–1255PubMedCrossRefGoogle Scholar
  8. Arvand M, Viezens J, Berghoff J (2008) Prolonged Bartonella henselae bacteremia caused by reinfection in cats. Emerg Infect Dis 14(1):152–154PubMedCentralPubMedCrossRefGoogle Scholar
  9. Bai Y, Kosoy M, Martin A, Ray C, Sheff K, Chalcraft L, Collinge SK (2008) Characterization of Bartonella strains isolated from black-tailed prairie dogs (Cynomys ludovicianus). Vector Borne Zoonotic Dis 8:1–6PubMedCrossRefGoogle Scholar
  10. Baker JA (1946) A rickettsial infection in Canadian voles. J Exp Med 84:37–51PubMedCentralCrossRefGoogle Scholar
  11. Barbian KD, Minnick MF (2000) A bacteriophage-like particle from Bartonella bacilliformis. Microbiology 146:599–609PubMedCrossRefGoogle Scholar
  12. Barton A (1909) Descripcionde elementos endoglobulares en los enfermos de Fiebre de Verruga. Cron Med Lima 26:7Google Scholar
  13. Bass JW, Vincent JM, Person DA (1997) The expanding spectrum of Bartonella infections. I. Bartonellosis and trench fever. Pediatr Infect Dis J 16:2–10PubMedCrossRefGoogle Scholar
  14. Bass JW, Freitas BC, Freitas AD, Sisler CL, Chan DS, Vincent JM, Person DA, Claybaugh JR, Wittler RR, Weisse ME, Regnery RL, Slater LN (1998) Prospective randomized double blind placebo-controlled evaluation of azithromycin for treatment of cat-scratch disease. Pediatr Infect Dis J 17(6):447–452PubMedCrossRefGoogle Scholar
  15. Battisti JM, Minnick MF (2008) Laboratory maintenance of Bartonella quintana. Curr Protoc Microbiol Unit 3C. New York, pp 1–13Google Scholar
  16. Bereswill S, Hinkelmann S, Kist M, Sander A (1999) Molecular analysis of riboflavin synthesis genes in Bartonella henselae and use of the ribC gene for differentiation of Bartonella species by PCR. J Clin Microbiol 37:3159–3166PubMedCentralPubMedGoogle Scholar
  17. Berglund EC, Frank AC, Calteau A, Vinnere Pettersson O, Granberg F (2009) Run-off replication of host-adaptability genes is associated with gene transfer agents in the genome of mouse-infecting Bartonella grahamii. PLoS Genet 5:e1000546PubMedCentralPubMedCrossRefGoogle Scholar
  18. Bergmans AMC (1996) Cat scratch disease: studies on diagnosis and identification of reservoirs and vectors. PhD Dissertation, Utrecht UniversityGoogle Scholar
  19. Bergmans AMC, Schellekens JFP, van Embden JDA, Schouls LM (1996) Predominance of two Bartonella henselae variants among cat-scratch disease patients in the Netherlands. J Clin Microbiol 34:254–260PubMedCentralPubMedGoogle Scholar
  20. Bermond D, Heller R, Barrat F, Delacour G, Dehio C, Alliot A, Monteil H, Chomel B, Boulouis HJ, Piémont Y (2000) Bartonella birtlesii sp. nov., isolated from small mammals (Apodemus spp.). Int J Syst Evol Microbiol 50:1973–1979PubMedCrossRefGoogle Scholar
  21. Bermond D, Boulouis HJ, Heller R, Van Laere G, Monteil H, Chomel BB, Sander A, Dehio C, Piémont Y (2002) Bartonella bovis Bermond et al. sp. nov. and Bartonella capreoli sp. nov., isolated from European ruminants. Int J Syst Evol Microbiol 52:383–390PubMedCrossRefGoogle Scholar
  22. Bernit E, Veit V, La Scola B, Tissot-Dupont H, Gachon J, Raoult D, Harle JR (2003) Bartonella quintana and Mycobacterium tuberculosis coinfection in an HIV-infected patient with lymphadenitis. J Infect 46:244–255PubMedCrossRefGoogle Scholar
  23. Birtles RJ, Raoult D (1996) Comparison of partial citrate synthase gene (gltA) sequences for phylogenetic analysis of Bartonella species. Int J Syst Bacteriol 46:891–897PubMedCrossRefGoogle Scholar
  24. Birtles RJ, Harrison TG, Fry NK, Saunders NA, Taylor AG (1991) Taxonomic considerations of Bartonella bacilliformis based on phylogenetic and phenotypic characteristics. FEMS Microbiol Lett 83:187–192Google Scholar
  25. Birtles RJ, Harrison TG, Molyneux DH (1994) Grahamella in small woodland mammals in the U.K.: isolation, prevalence and host specificity. Ann Trop Med Parasitol 88:317–327PubMedGoogle Scholar
  26. Birtles RJ, Harrison TG, Saunders NA, Molyneux DH (1995) Proposals to unify the genera Grahamella and Bartonella, with descriptions of Bartonella talpae comb. nov., Bartonella peromysci comb. nov., and three new species, Bartonella grahamii sp. nov., Bartonella taylorii sp. nov., and Bartonella doshiae sp. nov. Int J Syst Bacteriol 45:1–8PubMedCrossRefGoogle Scholar
  27. Birtles RJ, Canales J, Ventosilla P, Alvarez E, Guerra H, Llanos-Cuentas A, Raoult D, Doshi N, Harrison TG (1999) Survey of Bartonella species infecting intradomicillary animals in the Huayllacallan valley, Ancash, Peru, a region endemic for human bartonellosis. Am J Trop Med Hyg 60:799–805PubMedGoogle Scholar
  28. Birtles RJ, Hazel S, Bown K, Raoult D, Begon M, Bennett M (2000) Subtyping of uncultured Bartonellae using sequence comparison of 16S/23S rRNA intergenic spacer regions amplified directly from infected blood. Mol Cell Probes 14:79–87PubMedCrossRefGoogle Scholar
  29. Biswas S, Rolain JM (2010) Bartonella infection: treatment and drug resistance. Future Microbiol 5(11):1619–1731CrossRefGoogle Scholar
  30. Biswas S, Raoult D, Rolain JM (2006) Molecular characterization of resistance to macrolides in Bartonella henselae. Antimicrob Agents Chemother 50:3192–3193PubMedCentralPubMedCrossRefGoogle Scholar
  31. Biswas S, Raoult D, Rolain JM (2007) Molecular mechanisms of resistance to antibiotics in Bartonella bacilliformis. J Antimicrob Chemother 59:1065–1070PubMedCrossRefGoogle Scholar
  32. Biswas S, Raoult D, Rolain JM (2008) A bioinformatic approach to understanding antibiotic resistance in intracellular bacteria through whole genome analysis. Int J Antimicrob Agents 32(3):207–220PubMedCrossRefGoogle Scholar
  33. Biswas S, Maggi RG, Papich MG, Keil D, Breitschwerdt EB (2010) Comparative activity of pradofloxacin, enrofloxacin, and azithromycin against Bartonella henselae isolates collected from cats and a human. J Clin Microbiol 48(2):617–618PubMedCentralPubMedCrossRefGoogle Scholar
  34. Black JR, Herrington DA, Hadfield TL, Wear DJ, Margileth AM, Shigekawa B (1986) Life-threatening cat scratch disease in an immunocompromised host. Arch Intern Med 146:394–396PubMedCrossRefGoogle Scholar
  35. Blazes DL, Mullins K, Smoak BL, Jiang J, Canal E, Solorzano N, Laughlin L (2013) Novel Bartonella agent as cause of verruga peruana. Emerg Infect Dis 9:1111–1114CrossRefGoogle Scholar
  36. Boulouis HJ, Chang CC, Henn JB, Kasten RW, Chomel BB (2005) Factors associated with the rapid emergence of zoonotic Bartonella infections. Vet Res 36:383–410PubMedCrossRefGoogle Scholar
  37. Bown KJ, Bennet M, Begon M (2004) Flea-borne Bartonella grahamii and Bartonella taylorii in bank voles. Emerg Infect Dis 10:684–687PubMedCentralPubMedCrossRefGoogle Scholar
  38. Bradbury CA, Lappin MR (2010) Evaluation of topical application of 10% midacloprid—1% moxidectin to prevent Bartonella henselae transmission from cat fleas. J Am Vet Med Assoc 236(8):869–873PubMedCrossRefGoogle Scholar
  39. Breitschwerdt EB, Kordick DL, Malarkey DE, Keene B, Hadfield TL, Wilson K (1995) Endocarditis in a dog due to infection with a novel Bartonella subspecies. J Clin Microbiol 33:154–160PubMedCentralPubMedGoogle Scholar
  40. Breitschwerdt EB, Abrams-Ogg AC, Lappin MR, Bienzle D, Hancock SI, Cowan SM, Clooten JK, Hegarty BC, Hawkins EC (2002) Molecular evidence supporting Ehrlichia canis-like infection in cats. J Vet Intern Med 16:642–649PubMedGoogle Scholar
  41. Breitschwerdt EB, Blann ME, Stebbins KR, Muñana MG, Davidson HA, Jackson MD (2004) Willard: clinicopathologic abnormalities and treatment response in 24 dogs seroreactive to Bartonella vinsonii (berkhoffii) antigens. J Am Anim Hosp Assoc 40:92–101PubMedCrossRefGoogle Scholar
  42. Breitschwerdt EB, Maggi RG, Duncan AW, Nicholson WL, Hegarty BC, Woods CW (2007) Bartonella species in blood of immunocompetent persons with animal and arthropod contact. Emerg Infect Dis 13:938–941PubMedCentralPubMedCrossRefGoogle Scholar
  43. Breitschwerdt EB, Maggi RG, Robert Mozayeni B, Hegarty BC, Bradley JM, Mascarelli PE (2010) PCR amplification of Bartonella koehlerae from human blood and enrichment blood cultures. Parasit Vectors 3:76PubMedCentralPubMedCrossRefGoogle Scholar
  44. Brenner DJ, O’connor SP, Hollis DG, Weaver RE, Steigerwalt AG (1991) Molecular characterization and proposal of a neotype strain for Bartonella bacilliformis. J Clin Microbiol 29:1299–1302PubMedCentralPubMedGoogle Scholar
  45. Brenner DJ, O’connor SP, Winkler HH, Steigerwalt AG (1993) Proposals to unify the genera Bartonella and Rochalimaea, with descriptions of Bartonella quintana comb. nov., Bartonella vinsonii comb.nov., Bartonella henselae comb.nov., and Bartonella elizabethae comb.nov., and to remove the family Bartonellaceae from the order Rickettsiales. Int J Syst Bacteriol 43:777–786PubMedCrossRefGoogle Scholar
  46. Brenner SA, Rooney JA, Manzewitsch P, Regnery RL (1997) Isolation of Bartonella (Rochalimaea) henselae: effects of methods of blood collection and handling. J Clin Microbiol 35(3):544–547PubMedCentralPubMedGoogle Scholar
  47. Cadenas MB, Bradley J, Maggi RG, Takara M, Hegarty BC, Breitschwerdt EB (2008) Molecular characterization of Bartonella vinsonii subsp. berkhoffii genotype III. J Clin Microbiol 46:1858–1860PubMedCentralPubMedCrossRefGoogle Scholar
  48. Carithers HA (1985) Cat-scratch disease: an overview based on a study of 1200 patients. Am J Dis Child 139:1124–1133PubMedCrossRefGoogle Scholar
  49. Chamberlin J, Laughlin L, Gordon S, Romero S, Solórzano N, Regnery RL (2000) Serodiagnosis of Bartonella bacilliformis infection by indirect fluorescence antibody assay: test development and application to a population in an area of bartonellosis endemicity. J Clin Microbiol 38:4269–4271PubMedCentralPubMedGoogle Scholar
  50. Chang C, Yamamoto K, Chomel BB, Kasten RW, Simpson DC, Smith CR, Kramer VL (1999) Seroepidemiology of Bartonella vinsonii subsp. berkhoffii infection in California coyotes, 1994–1998. Emerg Infect Dis 5:711–715PubMedCentralPubMedCrossRefGoogle Scholar
  51. Chang C, Chomel BB, Kasten RW, Heller R, Kocan KM, Ueno H, Yamamoto K, Bleich VC, Pierce BM, Gonzales BJ, Swift PK, Boyce WM, Jang SS, Boulouis HJ, Piemont Y (2000) Bartonella spp. isolated from wild and domestic ruminants in North America. Emerg Infect Dis 6:306–311PubMedCentralPubMedCrossRefGoogle Scholar
  52. Chang CC, Chomel BB, Kasten RW, Romano V, Tietze N (2001) Molecular evidence of Bartonella spp. in questing adult Ixodes pacificus ticks in California. J Clin Microbiol 39:1221–1226PubMedCentralPubMedCrossRefGoogle Scholar
  53. Chang C-C, Hayashidani H, Pusterla N, Kasten RW, Madigan JE, Chomel BB (2002) Investigation of Bartonella infection in ixodid ticks from California. Comp Immunol Microbiol Infect Dis 25:229–236PubMedCrossRefGoogle Scholar
  54. Chenoweth MR, Somerville GA, Krause DC, O’Reilly KL, Gherardini FC (2004a) Growth characteristics of Bartonella henselae in a novel liquid medium: primary isolation, growth-phase-dependent phage induction, and metabolic studies. Appl Environ Microbiol 70:656–663PubMedCentralPubMedCrossRefGoogle Scholar
  55. Chenoweth MR, Greene CE, Krause DC, Gherardini FC (2004b) Predominant outer membrane antigens of Bartonella henselae. Infect Immun 72(6):3097–3105PubMedCentralPubMedCrossRefGoogle Scholar
  56. Cherry NA, Cannedy AL, Maggi RG, Breitschwerdt EB (2009) PCR detection of Bartonella bovis and Bartonella henselae in the blood of beef cattle. Vet Microbiol 135(3–4):308–312PubMedCrossRefGoogle Scholar
  57. Chmielewski T, Podsiadły E, Tylewska-Wierzbanowska S (2007) Presence of Bartonella spp. in various human populations. Pol J Microbiol 56(1):33–38PubMedGoogle Scholar
  58. Chomel BB, Kasten RW (2010) Bartonellosis, an increasingly recognized zoonosis. J Appl Microbiol 109:743–750PubMedCrossRefGoogle Scholar
  59. Chomel BB, Abbott RC, Kasten RW, Floyd-Hawkins KA, Kass PH, Glaser CA, Pedersen NC, Koehler JE (1995) Bartonella henselae prevalence in domestic cats in California: risk factors and association between bacteremia and antibody titers. J Clin Microbiol 33:2445–2450PubMedCentralPubMedGoogle Scholar
  60. Chomel BB, Kasten RW, Floyd-Hawkins K, Chi B, Yamamoto K et al (1996) Experimental transmission of Bartonella henselae by the cat flea. J Clin Microbiol 34:1952–1956PubMedCentralPubMedGoogle Scholar
  61. Chomel BB, Carlos ET, Kasten RW, Yamamoto K, Chang CC, Carlos RS, Abenes MV, Pajares CN (1999) Bartonella henselae and Bartonella clarridgeiae infection in domestic cats from the Philippines. Am J Trop Med Hyg 60:593–597PubMedGoogle Scholar
  62. Chomel BB, Mac Donald KA, Kasten RW, Chang CC, Wey AC, Foley JE, Thomas WP, Kittleson MD (2001) Aortic valve endocarditis in a dog due to Bartonella clarridgeiae. J Clin Microbiol 39:3548–3554PubMedCentralPubMedCrossRefGoogle Scholar
  63. Chomel BB, Kasten RW, Sykes JE, Boulouis HJ, Breitschwerdt EB (2003) Clinical impact of persistent Bartonella bacteremia in humans and animals. Ann N Y Acad Sci 990:267–278PubMedCrossRefGoogle Scholar
  64. Chomel BB, Boulouis H-J, Breitschwerdt EB (2004) Cat scratch disease and other zoonotic Bartonella infections. J Am Vet Med Assoc 224(8):1270–1279PubMedCrossRefGoogle Scholar
  65. Chomel BB, Boulouis HJ, Maruyama S, Breitschwerdt EB (2006) Bartonella spp. in pets and effect on human health. Emerg Infect Dis 12:389–394PubMedCentralPubMedCrossRefGoogle Scholar
  66. Chomel BB, Boulouis HJ, Breitschwerdt EB, Kasten RW, Vayssier-Taussat M, Birtles RJ, Koehler JE, Dehio C (2009) Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors. Vet Res 40(2):29PubMedCentralPubMedCrossRefGoogle Scholar
  67. Chomel BB, McMillan-Cole AC, Kasten RW, Stuckey MJ, Sato S, Maruyama S, Breitschwerdt EB (2012) Candidatus Bartonella merieuxii, a potential new zoonotic Bartonella species in canids from Iraq. PLos Negl Trop Dis 6(9):e1843PubMedCentralPubMedCrossRefGoogle Scholar
  68. Ciervo A, Mastroianni CM, Ajassa C, Pinto A, Ciceroni L (2005) Rapid identification of Bartonella henselae by real-time polymerase chain reaction in a patient with cat scratch disease. Diagn Microbiol Infect Dis 53:75–77PubMedCrossRefGoogle Scholar
  69. Cockerell CJ, LeBoit PE (1990) Bacillary angiomatosis: a newly characterized, pseudoneoplastic, infectious, cutaneous vascular disorder. J Am Acad Dermatol 22(3):501–512PubMedCrossRefGoogle Scholar
  70. Cockwill KR, Taylor SM, Philibert HM, Breitschwerdt EB, Maggi RG (2007) Bartonella vinsonii subsp. berkhoffii endocarditis in a dog from Saskatchewan. Can Vet J 48:839–844PubMedCentralPubMedGoogle Scholar
  71. Collins MD (1996) Description of Bartonella clarridgeiae sp. nov. isolated from the cat of a patient with Bartonella henselae septicemia. Med Microbiol Lett 5:64–73Google Scholar
  72. Conrad DA (2001) Treatment of cat-scratch disease. Curr Opin Pediatr 13(1):56–59PubMedCrossRefGoogle Scholar
  73. Cotte V, Bonnet S, Le Rhun D, Le Naour E, Chauvin A, Boulouis H-J, Lecuelle B, Lilin T, Vayssier-Taussat M (2008) Transmission of Bartonella henselae by Ixodes ricinus. Emerg Infect Dis 14(7):1074–1080PubMedCentralPubMedCrossRefGoogle Scholar
  74. Daly JS, Worthington MG, Brenner DJ, Moss WC, Hollis DG, Weyant RS, Steigerwalt AG, Weaver RE, Daneshvar MI, O’Connor SP (1993) Rochalimaea elizabethae sp. nov. isolated from a patient with endocarditis. J Clin Microbiol 31:872–881PubMedCentralPubMedGoogle Scholar
  75. Dehio C (2001) Bartonella interactions with endothelial cells and erythrocytes. Trends Microbiol 9:279–285PubMedCrossRefGoogle Scholar
  76. Dehio C (2004) Molecular and cellular basis of Bartonella pathogenesis. Annu Rev Microbiol 58:365–390PubMedCrossRefGoogle Scholar
  77. Dehio C (2005) Bartonella—host–cell interactions and vascular tumour formation. Nat Rev Microbiol 3:621–631PubMedCrossRefGoogle Scholar
  78. Dehio C (2008) Infection-associated type IV secretion systems of Bartonella and their diverse roles in host cell interaction. Cell Microbiol 10(8):1591–1598PubMedCentralPubMedCrossRefGoogle Scholar
  79. Dehio C, Sander A (1999) Bartonella as emerging pathogens. Trends Microbiol 7:226–228PubMedCrossRefGoogle Scholar
  80. Dehio C, Lanz C, Pohl R, Behrens P, Bermond D, Piémont Y, Pelz K, Sander A (2001) Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer. Int J Syst Evol Microbiol 51:1557–1565PubMedCrossRefGoogle Scholar
  81. Dehio C, Sauder U, Hiestand R (2004) Isolation of Bartonella schoenbuchensis from Lipoptena cervi, a blood-sucking arthropod causing deer ked dermatitis. J Clin Microbiol 42(11):5320–5323PubMedCentralPubMedCrossRefGoogle Scholar
  82. Didi K, Chaudhry R, Dhawa B (2013) Strategy for identification & characterization of Bartonella henselae with conventional & molecular methods. Indian J Med Res 137(2):380–387Google Scholar
  83. Diniz PPV, Maggi RG, Schwartz DS, Cadenas MB, Bradley JM, Breitschwerdt EB (2007) Canine bartonellosis: serological and molecular prevalence in Brazil and evidence of co-infection with Bartonella henselae and Bartonella vinsonii subsp. berkhoffii. Vet Res 38:697–710PubMedCrossRefGoogle Scholar
  84. Diniz PPVP, Wood M, Maggi RG, Sontakke S, Stepnik M, Breitschwerdt EB (2009) Co-isolation of Bartonella henselae and Bartonella vinsonii subsp. berkhoffii from blood, joint and subcutaneous seroma fluids from two naturally infected dogs. Vet Microbiol 138:368–372PubMedCrossRefGoogle Scholar
  85. Donatien A, Lestoquard F (1934) Sur une Bartonella nouvelle dubúuf, Bartonella bovis n. sp. Bull Soc Pathol Exot 7:652–654Google Scholar
  86. Doolittle WF (1999) Phylogenetic classification and the universal tree. Science 284:2124–2128PubMedCrossRefGoogle Scholar
  87. Dörbecker C, Sander A, Oberle K, Schülin-Casonato T (2006) In vitro susceptibility of Bartonella species to 17 antimicrobial compounds: comparison of Etest and agar dilution. J Antimicrob Chemother 58(4):784–788PubMedCrossRefGoogle Scholar
  88. Drancourt M, Birtles R, Chaumentin G, Vandenesch F, Etienne J, Raoult D (1996) New serotype of Bartonella henselae in endocarditis and cat-scratch disease. Lancet 347:441–443PubMedCrossRefGoogle Scholar
  89. Drancourt M, Mainardi JL, Brouqui P, Vandenesch F, Carta A, Lehnert F, Etienne J, Goldstein F, Acar J, Raoult D (1995) Bartonella (Rochalimaea) quintana endocarditis in three homeless men. N Engl J Med 332(7):419PubMedCrossRefGoogle Scholar
  90. Droz S, Chi B, Horn E, Steigerwalt AG, Whitney AM, Brenner DJ (1999) Bartonella koehlerae sp. nov., isolated from cats. J Clin Microbiol 37:1117–1122PubMedCentralPubMedGoogle Scholar
  91. Droz S, Chi B, Horn E, Streigerwalt AG, Whitney AM, Brenner DJ (2000) Validation of the publication of new names and new combinations previously effectively published outside the IJSB. List N 73. Int J Syst Evol Microbiol 50:423–424Google Scholar
  92. Duncan AW, Maggi RG, Breitschwerdt EB (2007) Bartonella DNA in dog saliva. Emerg Infect Dis 13:1948–1950PubMedCentralPubMedCrossRefGoogle Scholar
  93. Dyachenko P, Ziv M, Raz R, Chazan B, Lev A, Rozenman D (2005) Cat scratch disease encephalopathy in an immunocompetent patient. Eur J Intern Med 16:610–611PubMedCrossRefGoogle Scholar
  94. Ehrenborg C, Wesslen L, Jakobson A, Friman G, Holmberg M (2000) Sequence variation in the ftsZ gene of Bartonella henselae isolates and clinical samples. J Clin Microbiol 38:682–687PubMedCentralPubMedGoogle Scholar
  95. Ellis BA, Rotz LD, Leake JAD, Samalvides F, Bernable J, Ventura G, Padilha C, Villaseca P, Beati L, Regnery R, Childs JE, Olson JG, Carrilho CP et al (1999a) An outbreak of acute Bartonellosis (Oroya fever) in the Urubamba region of Peru, 1998. Am J Trop Med Hyg 61:344–349PubMedGoogle Scholar
  96. Ellis BA, Regnery RL, Beati L, Bacellar F, Rood M et al (1999b) Rats of the genus Rattus are reservoir hosts for pathogenic Bartonella species: an Old World origin for a New World disease? J Infect Dis 180:220–224PubMedCrossRefGoogle Scholar
  97. Eremeeva ME, Gerns HL, Lydy SL, Goo JS, Ryan ET, Mathew SS, Ferraro MJ, Holden JM, Nicholson WL, Dasch GA, Koehler JE (2007) Bacteremia, fever, and splenomegaly caused by a newly recognized Bartonella species. N Engl J Med 356:2381–2387PubMedCrossRefGoogle Scholar
  98. Eremeeva ME, Gerns HL, Lydy SL, Goo JS, Ryan ET, Mathew SS, Ferraro MJ, Holden JM, Nicholson WL, Dasch GA, Koehler JE (2012) Validation of the publication of new names and new combinations previously effectively published outside the IJSB. List N 144. Int J Syst Evol Microbiol 62:473–475Google Scholar
  99. Feng S, Kasten RW, Werner JA, Hodzic E, Barthold SW, Chomel BB (2009) Immunogenicity of Bartonella henselae P26 in cats. Vet Immunol Immunopathol 132(2–4):251–256PubMedCrossRefGoogle Scholar
  100. Fox GE, Wisotzkey JD, Jurtshuk PJ Jr (1992) How close is close: 16S rRNA sequence identity may not be sufficient to guarantee species identity. Int J Syst Bacteriol 42:166–170PubMedCrossRefGoogle Scholar
  101. Frye JG, Porwollik S, Blackmer F, Cheng P, McClelland M (2005) Host gene expression changes and DNA amplification during temperate phage induction. J Bacteriol 187:1485–1492PubMedCentralPubMedCrossRefGoogle Scholar
  102. Fukasawa T, Hirai K, Segawa T, Obonai K (1978) Regional replication of the bacterial chromosome induced by derepression of prophage lambda. IV. Escape synthesis of gal operon in phage 82. Mol Gen Genet 167:83–93PubMedGoogle Scholar
  103. Gieszczykiewicz M (1939) Bulletin de 1’Academie Polonaise des Sciences. Serie des Sciences Biologiques 1:9–27Google Scholar
  104. Giladi M, Kletter Y, Avidor B, Metzkor-Cotter E, Varon M, Golan Y, Weinberg M, Riklis I, Ephros M, Slater L (2001) Enzyme immunoassay for the diagnosis of cat-scratch disease defined by polymerase chain reaction. Clin Infect Dis 33:1852–1858PubMedCrossRefGoogle Scholar
  105. Glaus R, Hofmann-Lehmann C et al (1997) Seroprevalence of Bartonella henselae infection and correlation with disease status in cats in Switzerland. J Clin Microbiol 35(11):2883–2885PubMedCentralPubMedGoogle Scholar
  106. Greene CE, McDermott M, Jameson PH, Atkins CL, Marks AM (1996) Bartonella henselae infection in cats: evaluation during primary infection, treatment, and rechallenge infection. J Clin Microbiol 34(7):1682–1685PubMedCentralPubMedGoogle Scholar
  107. Greub G, Raoult D (2002) Bartonella: new explanations for old diseases. J Med Microbiol 51:915–923PubMedCrossRefGoogle Scholar
  108. Gundi VAKB, Taylor C, Raoult D, La Scola B (2009) Bartonella rattaustraliani sp. nov., Bartonella queenslandensis sp. nov. and Bartonella coopersplainsensis sp. nov., identified in Australian rats. Int J Syst Evol Microbiol 59:2956–2961PubMedCrossRefGoogle Scholar
  109. Guptill L (2003) Bartonellosis. Vet Clin Small Anim Pract 33:809–825CrossRefGoogle Scholar
  110. Guptill L (2010) Bartonellosis. Vet Microbiol 140:347–359PubMedCrossRefGoogle Scholar
  111. Guptill L, Slater L, Wu CC, Glickman LT, Lin TL, Crippen JT, Hogen Esch H (1999) Immune response of neonatal specific pathogen-free cats to experimental infection with Bartonella henselae. Vet Immunol Immunopathol 71:233–243PubMedCrossRefGoogle Scholar
  112. Guptill L, Wu CC, Hogen Esch H, Slater LN, Glickman NW, Dunham AD, Syme HM, Glickman LT (2004) Prevalence, risk factors, and genetic diversity of Bartonella henselae infections in pet cats in four regions of the United States. J Clin Microbiol 42(2):652–659PubMedCentralPubMedCrossRefGoogle Scholar
  113. Gurfield AN, Boulouis H-J, Chomel BB, Heller R, Kasten RW, Yamamoto K, Piemont Y (1997) Coinfection with Bartonella clarridgeiae and Bartonella henselae and with different Bartonella henselae strains in domestic cats. J Clin Microbiol 35(8):2120–2123PubMedCentralPubMedGoogle Scholar
  114. Habib G, Hoen B, Tornos P, Thuny F, Prendergast B, Vilacosta I, Rosenhek R (2009) Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009) The Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Eur Heart J 30(19):2369–2413PubMedCrossRefGoogle Scholar
  115. Hammoud KA, Hinthorn D, Edwards B (2008) Bartonellosis. article 213169
  116. Harms A, Dehio C (2012) Intruders below the radar: molecular pathogenesis of Bartonella spp. Clin Microbiol Rev 25:42–78PubMedCentralPubMedCrossRefGoogle Scholar
  117. Heller R, Riegel P, Hansmann Y, Delacour G, Bermond D, Dehio C, Lamarque F, Monteil H, Chomel B, Piémont Y (1998) Bartonella tribocorum sp. nov., a new Bartonella species isolated from the blood of wild rats. Int J Syst Bacteriol 48:1333–1339PubMedCrossRefGoogle Scholar
  118. Heller R, Kubina M, Mariet P, Riegel P, Delacour G, Dehio C, Lamarque F, Kasten R, Boulouis HJ, Monteil H, Chomel B, Piémont Y (1999) Bartonella alsatica sp. nov., a new Bartonella species isolated from the blood of wild rabbits. Int J Syst Bacteriol 49:283–288PubMedCrossRefGoogle Scholar
  119. Henn JB, Gabriel MW, Kasten RW, Brown RN, Koehler JE, MacDonald KA, Kittleson MD, Thomas WP, Chomel BB (2009a) Infective endocarditis in a dog and the phylogenetic relationship of the associated “Bartonella rochalimae” strain with isolates from dogs, gray foxes, and a human. J Clin Microbiol 47:787–790PubMedCentralPubMedCrossRefGoogle Scholar
  120. Henn JB, Chomel BB, Boulouis HJ, Kasten RW, Murray WJ, Bar-Gal GK, King R, Courreau JF, Baneth G (2009b) Bartonella rochalimae in raccoons, coyotes and red foxes. Emerg Infect Dis 15:1984–1987PubMedCentralPubMedCrossRefGoogle Scholar
  121. Higgins JA, Radulovic S, Jaworski DC, Azad AF (1996) Acquisition of the cat scratch disease agent Bartonella henselae by cat fleas (Siphonaptera: Pulicidae). J Med Entomol 33:490–495PubMedCrossRefGoogle Scholar
  122. Hoey JG, Valois-Cruz F, Goldenberg H, Voskoboynik Y, Pfi!ner J, Tilton RC, Mordechai E, Adelson ME (2009) Development of an immunoglobulin M capture-based enzymelinked immunosorbent assay for diagnosis of acute infections with Bartonella henselae. Clin Vaccine Immunol 16:282–284PubMedCentralPubMedCrossRefGoogle Scholar
  123. Houpikian P, Fournier E, Raoult D (2001) Phylogenetic position of Bartonella vinsonii subsp. arupensis based on 16S rDNA and gltA gene sequences. Int J Syst Evolutionary Microbiol 51:179–182CrossRefGoogle Scholar
  124. Houpikian P, Raoult D (2001a) Molecular phylogeny of the genus Bartonella: what is the current knowledge? FEMS Microbiol Lett 200:1–7PubMedCrossRefGoogle Scholar
  125. Houpikian P, Raoult D (2001b) 16S/23SrRNA intergenic spacer regions for phylogenetic analysis, identification, and subtyping of Bartonella species. J Clin Microbiol 39:2768–2778PubMedCentralPubMedCrossRefGoogle Scholar
  126. Houpikian P, Raoult D (2002) Diagnostic methods: current best practices and guidelines for identification of difficult-to-culture pathogens in infective endocarditis. Infect Dis Clin North Am 16(2):377–392PubMedCrossRefGoogle Scholar
  127. Inoue K, Kabeya H, Shiratori H, Ueda K, Kosoy MY, Chomel BB, Boulouis HJ, Maruyama S (2010) Bartonella japonica sp. nov. and Bartonella silvatica sp. nov., isolated from Apodemus mice. Int J Syst Evol Microbiol 60:759–763PubMedCrossRefGoogle Scholar
  128. Ives TJ, Manzewitsch P, Regnery RL, Butts JD, Kebede M (1997) In vitro susceptibilities of Bartonella henselae, B. quintana, B. elizabethae, Rickettsia rickettsii, R. conorii, R. akari, and R. prowazekii to macrolide antibiotics as determined by immunofluorescent-antibody analysis of infected Vero cell monolayers. Antimicrob Agents Chemother 41(3):578–582PubMedCentralPubMedGoogle Scholar
  129. Jacomo V, Kelly PJ, Raoult D (2002) Natural history of Bartonella infections (an exception to Koch’s postulate). Clin Diagn Lab Immunol 9:8–18PubMedCentralPubMedGoogle Scholar
  130. Jensen WA, Majilinde ZF, Rooney J, Kordick DL, Breitschwerdt EB (2000) Rapid identification and differentiation of Bartonella species using a single-step PCR assay. J Clin Microbiol 38:1717–1722PubMedCentralPubMedGoogle Scholar
  131. Johnson G, Ayers M, McClure SCC, Richardson SE, Tellier R (2003) Detection and identification of Bartonella species pathogenic for humans by PCR amplification targeting the riboflavin synthase gene (ribC). J Clin Microbiol 4:1069–1072CrossRefGoogle Scholar
  132. Kabeya H, Maruyama S, Irei M, Takahashi R, Yamashita M, Mikami T (2002) Genomic variations among Bartonella henselae isolates derived from naturally infected cats. Vet Microbiol 89:211–221PubMedCrossRefGoogle Scholar
  133. Kabeya H, Maruyama S, Hirano K, Mikami T (2003) Cloning and expression of Bartonella henselae sucB gene encoding an immunogenic dihydrolipoamide succinyltransferase homologous protein. Microbiol Immunol 47:571–576PubMedCrossRefGoogle Scholar
  134. Kaewmongkol G, Kaewmongkol S, Burmej H, Bennett MD, Fleming PA, Adams PJ, Fenwick SG (2011a) Diversity of Bartonella species detected in arthropod vectors from animals in Australia. Comp Immunol Microbiol Infect Dis 34:411–417PubMedCrossRefGoogle Scholar
  135. Kaewmongkol G, Kaewmongkol S, Owen H, Fleming PA, Adams PJ, Ryan U, Fenwick G (2011b) Candidatus Bartonella antechini: a novel Bartonella species detected in fleas and ticks from the yellow-footed antechinus (Antechinus flavipes), an Australian marsupial. Vet Microbiol 149:517–521PubMedCrossRefGoogle Scholar
  136. Kaiser PO, Riess T, Wagner CL, Linke D, Lupas AN (2008) The head of Bartonella adhesin A is crucial for host cell interaction of Bartonella henselae. Cell Microbiol 10:2223–2234PubMedCrossRefGoogle Scholar
  137. Kaiser PO, Riess T, O’Rourke F, Linke D, Kempf VAJ (2011) Bartonella spp.: throwing light on uncommon human infections. Int J Med Microbiol 301:7–15PubMedCrossRefGoogle Scholar
  138. Kelly TM, Padmalayam I, Baumstarck BR (1998) Use of the cell division protein ftsZ as a means of differentiating among Bartonella species. Clin Diagn Lab Immunol 5:766–772PubMedCentralPubMedGoogle Scholar
  139. Kelly P, Rolain JM, Maggi R, Sontakke S, Keene B, Hunter S, Lepidi H, Breitschwerdt KT, Breitschwerdt EB, Raoult D (2006) Bartonella quintana endocarditis in dogs. Emerg Infect Dis 12:1869–1872PubMedCentralPubMedCrossRefGoogle Scholar
  140. Kerkhoff FT, Bergmans AM, Van Der Z, Rothova A (1999) Demonstration of Bartonella grahamii DNA in ocular fluids of a patient with neuroretinitis. J Clin Microbiol 37:4034–4038PubMedCentralPubMedGoogle Scholar
  141. Ketring KL, Zuckerman EE, Jr Hardy WD (2004) Bartonella: a new etiological agent of feline ocular disease. J Am Anim Hosp Assoc 40:6–12PubMedCrossRefGoogle Scholar
  142. Klotz SA, Ianas V, Elliott SP (2011) Cat-scratch disease. Am Fam Physician 83(2):152–155PubMedGoogle Scholar
  143. Koehler JE (1995) Bartonella–associated infections in HIV–infected patients. Aids Clin Care 7:97–102PubMedGoogle Scholar
  144. Koehler JE, Tappero JW (1993) Bacillary angiomatosis and bacillary peliosis in patients with human immunodeficiency virus. Clin Infect Dis 17(4):612–624PubMedCrossRefGoogle Scholar
  145. Koehler JE, Quinn FD, Berger TG, Leboit PE, Tappero JW (1992) Isolation of Rochalimaea species from cutaneous and osseous lesions of bacillary angiomatosis. N Engl J Med 327:1625–1631PubMedCrossRefGoogle Scholar
  146. Koehler JE, Glaser CA, Tappero JW (1994) Rochalimaea henselae infection: a new zoonosis with the domestic cat as reservoir. J Am Med Assoc 271:531–535CrossRefGoogle Scholar
  147. Koehler JE, Sanchez MA, Garrido CS, Whitfeld MJ, Chen FM, Berger TG, Rodriguez-Barradas MC, Leboit PE, Tappero JW (1997) Molecular epidemiology of Bartonella infections in patients with bacillary angiomatosis-peliosis. N Engl J Med 337:1876–1883PubMedCrossRefGoogle Scholar
  148. Koesling J, Aebischer T, Falch C, Schulein R, Dehio C (2001) Cutting edge: antibody-mediated cessation of hemotropic infection by the intraerythrocytic mouse pathogen Bartonella grahamii. J Immunol 167:11–14PubMedCrossRefGoogle Scholar
  149. Koneman EW (2006) Koneman’s color atlas and textbook of diagnostic microbiology. Lippincott Williams & Wilkins, Philadelphia, 1565 ppGoogle Scholar
  150. Kordick DL, Breitschwerdt EB (1997) Relapsing bacteremia after blood transmission of Bartonella henselae to cats. Am J Vet Res 58:492–497PubMedGoogle Scholar
  151. Kordick DL, Breitschwerdt EB (1998) Persistent infection of pets within a household with three Bartonella species. Emerg Infect Dis 4:325–328PubMedCentralPubMedCrossRefGoogle Scholar
  152. Kordick DL, Wilson KH, Sexton DJ, Hadfield TL, Berkhoff HA, Breitschwerdt EB (1995) Prolonged Bartonella bacteremia in cats associated with cat-scratch disease patients. J Clin Microbiol 33(12):3245–3251PubMedCentralPubMedGoogle Scholar
  153. Kordick DL, Swaminathan B, Greene CE, Wilson KH, Whitney AM, O’connor S, Hollis DG, Matar GM, Steigerwalt AG, Malcolm GB, Hayes PS, Hadfield TL, Breitschwerdt EB, Brenner DJ (1996) Bartonella vinsonii subsp. berkhoffii subsp. nov., isolated from dogs; Bartonella vinsonii subsp. vinsonii; and emended description of Bartonella vinsonii. Int J Syst Bacteriol 46:704–709PubMedCrossRefGoogle Scholar
  154. Kordick DL, Hiljard EJ, Hadfield TL, Wilson KH, Steigerwalt AG, Brenner DJ, Breitschwerdt EB (1997) Bartonella clarridgeiae, a newly recognized zoonotic pathogen causing inoculation papules, fever, and lymphadenopathy (cat scratch disease). J Clin Microbiol 35:1813–1818PubMedCentralPubMedGoogle Scholar
  155. Kordick DL, Brown TT, Shin K, Breitschwerdt EB (1999) Clinical and pathologic evaluation of chronic Bartonella henselae or Bartonella clarridgeiae infection in cats. J Clin Microbiol 37(5):1536–1547PubMedCentralPubMedGoogle Scholar
  156. Kosoy MY, Regnery RL, Tzianabos T, Marston EL, Jones DC, Green D, Maupin GO, Olson JG, Childs JE (1997) Distribution, diversity, and host specificity of Bartonella in rodents from the southeastern United States. Am J Trop Med Hyg 57:578–588PubMedGoogle Scholar
  157. Kosoy M, Morway C, Sheff K, Bai Y, Colborn J, Chalcraft L, Peruski L, Dowell S, Peruski L, Maloney S, Baggett H, Sutthirattana S, Sidhirat A, Maruyama S, Kabeya H, Chomel B, Kasten R, Popov V, Robinson J, Kruglov A, Petersen L (2008) Bartonella tamiae sp. nov., a newly recognized pathogen isolated from three human patients from Thailand. Int J Clin Microbiol 46:772–775CrossRefGoogle Scholar
  158. Kostrzewski J (1949) The epidemiology of trench fever. Bull Acad Pol Sci Lett Classe Med 7:233–263Google Scholar
  159. La Scola B, Raoult D (1999) Culture of Bartonella quintana and Bartonella henselae from human samples: a 5-year experience (1993 to 1998). J Clin Microbiol 37(6):1899–1905PubMedCentralPubMedGoogle Scholar
  160. La Scola B, Fournier PE, Brouqui P, Raoult D (2001) Detection and culture of Bartonella quintana, Serratia marcescens and Acinetobacter spp. from decontaminated human body lice. J Clin Microbiol 39:1707–1709. doi:10.1128/JCM.39.5.1707-1709PubMedCentralPubMedCrossRefGoogle Scholar
  161. La VD, Tran-Hung L, Aboudharam G, Raoult D, Drancourt M (2005) Bartonella quintana in domestic cat. Emerg Infect Dis 11:1287–1289PubMedCentralPubMedCrossRefGoogle Scholar
  162. Lamas C, Curi A, Bóia MN, Lemos ERS (2008) Human bartonellosis: seroepidemiological and clinical aspects with emphasis on data from Brazil—a review. Mem Inst Oswaldo Cruz 103:221–235PubMedCrossRefGoogle Scholar
  163. Lappin MR, Breitschwerdt EB, Brewer M, Hawley J, Hegargy B, Radecki S (2008) Prevalence of Bartonella species antibodies and Bartonella species DNA in the blood of cats with and without fever. J Feline Med Surg 11(2):141–148PubMedCrossRefGoogle Scholar
  164. Larson AM, Dougherty MJ, Nowowiejski DJ, Welch DF, Matar GM, Swaminathan B, Coyle MB (1994) Detection of Bartonella (Rochalimaea) quintana by routine acridine orange staining of broth blood cultures. J Clin Microbiol 32:1492–1496PubMedCentralPubMedGoogle Scholar
  165. Lawson PA, Collins MD (1996) Description of Bartonella clarridgeiae sp. nov. isolated from the cat of a patient with Bartonella henselae septicemia. Med Microbiol Lett 5:64–73Google Scholar
  166. Leibovitz K, Pearce L, Brewer M, Lappin MR (2008) Bartonella species antibodies and DNA in cerebral spinal fluid of cats with central nervous system disease. J Feline Med Surg 10:332–337PubMedCrossRefGoogle Scholar
  167. Lepidi H, Casalta J-P, Gouriet F, Collart F, Habib G, Raoult D (2008) Infective endocarditis incidentally discovered by pathological examination. J Clin Pathol 61:233–234PubMedCrossRefGoogle Scholar
  168. Lin EY, Tsigrelis C, Baddour LM, Lepidi H, Rolain JM, Patel R, Raoult D (2010) Candidatus Bartonella mayotimonensis and endocarditis. Emerg Infect Dis 16:500–503PubMedCentralPubMedCrossRefGoogle Scholar
  169. Lindroos H, Vinnere O, Mira A, Repsilber D, Naslund K (2006) Genome rearrangements, deletions, and amplifications in the natural population of Bartonella henselae. J Bacteriol 188:7426–7439PubMedCentralPubMedCrossRefGoogle Scholar
  170. Litwin CM, Rawlins ML, Swenson EM (2007) Characterization of an immunogenic outer membrane autotransporter protein, Arp, of Bartonella henselae. Infect Immun 75:5255–5263PubMedCentralPubMedCrossRefGoogle Scholar
  171. Loa CC, Mordechai E, Tilton RC, Adelson ME (2006) Production of recombinant Bartonella henselae 17-kDa protein for antibody-capture enzyme-linked immunosorbent assay. Diagn Microbiol Infect Dis 55:1–7PubMedCrossRefGoogle Scholar
  172. Lucey D, Dolan MJ, Moss CW, Garcia M, Hollis DG, Wegner S, Morgan G, Almeida R, Leong D, Greisen KS, Welch DF, Slater LN (1992) Relapsing illness due to Rochalimaea henselae in immunocompetent hosts: implication for therapy and new epidemiological associations. Clin Infect Dis 14:683–688 (Abstract)PubMedCrossRefGoogle Scholar
  173. Ludwig W, Schleifer KH (1999) Phylogeny of Bacteria beyond the 16S rRNA standard. ASM News 65:752–757Google Scholar
  174. Lydy SL, Eremeeva ME, Asnis D, Paddock CD, Nicholson WL, Silverman DJ, Dasch GA (2008) Isolation and characterization of Bartonella bacilliformis from an expatriate Ecuadorian. J Clin Microbiol 46:627–637PubMedCentralPubMedCrossRefGoogle Scholar
  175. Lynch T, Iverson J, Kosoy M (2011) Combining culture techniques for Bartonella: the best of both worlds. Int J Clin Microbiol 49(4):1363–1368CrossRefGoogle Scholar
  176. MacKichan JK, Gerns HL, Chen Y, Zhang P, Koehler JE (2008) A SacB mutagenesis strategy reveals that the Bartonella quintana variably expressed outer membrane proteins are required for bloodstream infection of the host. Infect Immun 76:788–795PubMedCentralPubMedCrossRefGoogle Scholar
  177. Maggi RG, Breitschwerdt EB (2005) Isolation of bacteriophages from Bartonella vinsonii subsp. berkhoffii and the characterization of Pap31 gene sequences from bacterial and phage DNA. J Mol Microbiol Biotechnol 9:44–51PubMedCrossRefGoogle Scholar
  178. Maggi RG, Duncan AW, Breitschwerdt EB (2005a) Novel chemically modified liquid medium that will support the growth of seven Bartonella species. J Clin Microbiol 43(6):2651–2655PubMedCentralPubMedCrossRefGoogle Scholar
  179. Maggi RG, Harms CA, Hohn AA, Pabst DA, McLellan WA, Walton WJ, Rotstein DS, Breitschwerdt EB (2005b) Bartonella henselae in porpoise blood. Emerg Infect Dis 11(12):1894–1898PubMedCentralPubMedCrossRefGoogle Scholar
  180. Maguina Vargas, C (1998) Bartonellosis o enfermedad de carrion. Nuevos aspectos de una vieja enfermedad, p. 7–195. AFA Editores Importadores, Lima, PeruGoogle Scholar
  181. Maguina C, Gotuzzo E (2000) Bartonellosis. New and old. Infect Dis Clin North Am 14:1–22PubMedCrossRefGoogle Scholar
  182. Maguina C, Garcia PJ, Gotuzzo E, Cordero L, Spach DH (2001) Bartonellosis (Carrion’s disease) in the modern era. Clin Infect Dis 33:772–779PubMedCrossRefGoogle Scholar
  183. Maillard R, Riegel P, Barrat F, Bouillin C, Thibault D, Gandoin C, Halos L, Demanche C, Alliot A, Guillot J, Piémont Y, Boulouis HJ, Vayssier-Taussat M (2004) Bartonella chomelii sp. nov., isolated from French domestic cattle (Bos taurus). Int J Syst Evol Microbiol 54:215–220PubMedCrossRefGoogle Scholar
  184. Marakaki S, Sotiropoulou M, Papaspirou P, Lazaris D (2003) Cat scratch disease presenting as a solitary tumor in the breast: report of three cases. Reprod Biol 106:175–178Google Scholar
  185. Margileth A, Baehren DF (1998) Chest wall abscess due to cat-scratch disease (CSD) in an adult with antibodies to Bartonella clarridgeiae: case report and review of the thoracopulmonary manifestations of CSD. Clin Infect Dis 27:353–357PubMedCrossRefGoogle Scholar
  186. Marston EL, Sumner JW, Regnery RL (1999) Evaluation of intraspecies genetic variation within the 60 kDa heat-shock protein gene (groEL) of Bartonella species. Int J Syst Bacteriol 49:1015–1023PubMedCrossRefGoogle Scholar
  187. Matsuoka M, Sasaki T, Seki N, Kobayashi M, Sawabe K, Sasaki Y, Shibayama K, Sasaki T, Arakawa Y (2013) Hemin-binding proteins as potent markers for serological diagnosis of infections with Bartonella quintana. Clin Vaccine Immunol 20(4):620–626PubMedCentralPubMedCrossRefGoogle Scholar
  188. Maurin M, Raoult D (1993) Antimicrobial susceptibility of Rochalimaea quintana, Rochalimaea vinsonii, and the newly recognized Rochalimaea henselae. J Antimicrob Chemother 32:587–594PubMedCrossRefGoogle Scholar
  189. Maurin M, Raoult D (1996) Bartonella (Rochalimaea) quintana infections. Clin Microbiol Rev 9:273–292PubMedCentralPubMedGoogle Scholar
  190. Maurin M, Roux V, Stein A, Ferrier F, Viraben R, Raoult D (1994) Isolation and characterization by immunofluorescence, sodium dodecyl sulfate-polyacrylamide gel electrophoresis, Western blot, restriction fragment length polymorphism-PCR, 16S rRNA gene sequencing, and pulsed-field gel electrophoresis of Rochalimaea quintana from a French patient with bacillary angiomatosis. J Clin Microbiol 32:1166–1171PubMedCentralPubMedGoogle Scholar
  191. Maurin M, Gasquet S, Ducco C, Raoult D (1995) MICs of 28 antibiotic compounds for 14 Bartonella (formerly Rochalimaea) isolates. Antimicrob Agents Chemother 39(11):2387–2391PubMedCentralPubMedCrossRefGoogle Scholar
  192. Maurin M, Eb F, Etienne J, Raoult D (1997) Serological cross-reactions between Bartonella and Chlamydia species: implications for diagnosis. J Clin Microbiol 35:2283–2287PubMedCentralPubMedGoogle Scholar
  193. McGill S, Regnery R, Karem K (1998) Characterization of human immunoglobulin (Ig) isotype and IgG subclass response to Bartonella henselae infection. Infect Immun 66(12):5915–5920PubMedCentralPubMedGoogle Scholar
  194. Meghari S, Rolain JM, Grau GE, Platt E, Barrassi L, Mege JL, Raoult D (2006) Anti-angiogenic effect of erythromycin in Bartonella quintana: in vitro model of infection. J Infect Dis 193:380–386PubMedCrossRefGoogle Scholar
  195. Mehock JR, Greene CE, Gherardini FC, Hahn TW, Krause DC (1998) Bartonella henselae invasion of feline erythrocytes in vitro. Infect Immun 66:3462–3466PubMedCentralPubMedGoogle Scholar
  196. Mexas AM, Hancock SI, Breitschwerdt EB (2002) Bartonella henselae and Bartonella elizabethae as potential canine pathogens. J Clin Microbiol 40(12):4670-4674PubMedCentralPubMedCrossRefGoogle Scholar
  197. Minnick MF, Anderson BE (2006) The genus Bartonella. In: Dworkin M, Falkow S, Rosenberg E, Schleifer KH, Stackebrandt E (eds) The prokaryotes: a handbook on the biology of bacteria. Springer, New York, pp 467–492CrossRefGoogle Scholar
  198. Minnick MF, Battisti JF (2009) Pestilence, persistence and pathogenicity: infection strategies of Bartonella. Future Microbiol 4(6):743–758PubMedCentralPubMedCrossRefGoogle Scholar
  199. Mogollon-Pasapera E, Otvos L Jr, Giordano A, Cassone M (2009) Bartonella: emerging pathogen or emerging awareness? Int J Infect Dis 13:3–8PubMedCrossRefGoogle Scholar
  200. Muñana KR, Vitek SM, Hegarty BC, Kordick DI, Breitschwerdt EB (2001) Infection of fetal feline brain cells in culture with Bartonella henselae. Infect Immun 69:564–569PubMedCentralPubMedCrossRefGoogle Scholar
  201. Nystedt B, Frank AC, Thollesson M, Andersson SGE (2008) Diversifying selection and concerted evolution of a type IV secretion system in Bartonella. Mol Biol Evol 25:287–300PubMedCrossRefGoogle Scholar
  202. O’Reilly KL, Bauer RW, Freeland RL, Foil LD, Hughes KJ, Rohde KR, Roy AF, Stout RW, Triche PC (1999) Acute clinical disease in cats following infection with a pathogenic strain of Bartonella henselae (LSU16). Infect Immun 67:3066–3072PubMedCentralPubMedGoogle Scholar
  203. Oksi J, Rantala S, Kilpinen S, Silvennoinen R, Vornanen M, Veikkolainen V, Eerola E, Pulliainen AT (2013) Cat scratch disease caused by Bartonella grahamii in an immunocompromised patient. J Clin Microbiol 51:2781–2784PubMedCentralPubMedCrossRefGoogle Scholar
  204. Oliveira AM, Maggi RG, Woods CW, Breitschwerdt EB (2010) Putative needle stick transmission of Bartonella vinsonii subsp. berkhoffii to a veterinarian. J Vet Intern Med 24:1229–1232PubMedCrossRefGoogle Scholar
  205. Olsen GJ, Woese CR (1993) Ribosomal RNA: a key to phylogeny. FASEB J 7:113–123PubMedGoogle Scholar
  206. Pachas P (2000) Epidemiología de la Bartonelosis en el Peru. Oficina General de Epidemiología, LimaGoogle Scholar
  207. Pappalardo BL, Correa MT, York CC, Peat CY, Breitschwerdt EB (1997) Epidemiologic evaluation of the risk factors associated with exposure and seroreactivity to Bartonella vinsonii in dogs. Am J Vet Res 58(5):467–471PubMedGoogle Scholar
  208. Pappalardo BL, Brown T, Gebhardt D, Sontakke S, Breitschwerdt EB (2000) Cyclic CD8+ lymphopenia in dogs experimentally infected with Bartonella vinsonii subsp. berkhoffii. Vet Immunol Immunopathol 75:43–57PubMedCrossRefGoogle Scholar
  209. Pappalardo BL, Brown TT, Tompkins M, Breitschwerdt EB (2001) Immunopathology of Bartonella vinsonii (berkhoffii) in experimentally infected dogs. Vet Immunol Immunopathol 83:125–147PubMedCrossRefGoogle Scholar
  210. Pasavento PA, Chomel BB, Kasten RW, McDonald KA, Mohr FC (2005) Pathology of Bartonella endocarditis in six dogs. Vet Pathol 42:370–373CrossRefGoogle Scholar
  211. Pérez-Martínez L, Blanco JR, Oteo JA (2010) Treatment of human infections caused by Bartonella spp. Rev Esp Quimioter 23(3):109-114PubMedGoogle Scholar
  212. Perkocha LA, Geaghan SM, Yen TS, Nishimura SL, Chan SP, Garcia-Kennedy R, Honda G, Stoloff AC, Klein HZ, Goldman RL, Van Meter S, Ferrel L, Leboit PE (1990) Clinical and pathological features of bacillary peliosis hepatis in association with human immunodeficiency virus infection. N Engl J Med 323:1581–1586PubMedCrossRefGoogle Scholar
  213. Pressler B (2006) Bartonellosis. In: August RJ (ed) Consultation in feline internal medicine. Elsevier/Saunders, Philadelphia, pp 29–37CrossRefGoogle Scholar
  214. Prutsky G, Domecq JP, Mori L, Bebko S, Matzumura M, Sabouni A, Shahrour A, Erwin PJ, Boyce TG, Montori VM, Malaga G, Murad MH (2013) Treatment outcomes of human bartonellosis: a systematic review and meta-analysis. Int J Infect Dis 17:811–819CrossRefGoogle Scholar
  215. Raoult D, Drancourt M, Carta A, Gastaut JA (1994) Bartonella (Rochalimaea) quintana isolation in patient with chronic adenopathy, lymphopenia, and a cat. Lancet 343(8903):977–977PubMedCrossRefGoogle Scholar
  216. Raoult D, Foucault C, Brouqui P (2001) Infections in the homeless. Lancet Infect Dis 1:77–84PubMedCrossRefGoogle Scholar
  217. Raoult D, Roblot F, Rolain JM, Besnier JM, Loulergue J, Bastides F et al (2006) First isolation of Bartonellaalsatica from a valve of a patient with endocarditis. J Clin Microbiol 44:278–279PubMedCentralPubMedCrossRefGoogle Scholar
  218. Raoult D, Foucault C, Brouqui P (2001) Infections in the homeless. Lancet Infect Dis 1:77–84PubMedCrossRefGoogle Scholar
  219. Raoult D, Fournier PE, Vandenesch F, Mainardi JL, Eykyn SJ, Nash J, James E, Benoit-Lemercier C, Marrier TJ (2003) Outcome and treatment of Bartonella endocarditis. Arch Intern Med 163:26–230CrossRefGoogle Scholar
  220. Reed JB, Scales DK, Wong MT, Lattuada CP Jr, Dolan MJ, Schwab IR (1998) Bartonella henselae neuroretinitis in cat-scratch disease. Diagnosis, management and sequelae. Ophthalmology 105:459–466PubMedCrossRefGoogle Scholar
  221. Regnery RL, Anderson BE, Clarridge JE III, Rodriquez-Barradas MC, Jones DC, Carr JH (1992) Characterization of a novel Rochalimaea species, R. henselae sp. nov., isolated from blood of a febrile, human immunodeficiency virus-positive patient. J Clin Microbiol 30:265–274PubMedCentralPubMedGoogle Scholar
  222. Regnery RL, Rooney JA, Johnson AM, Nesby SL, Manzewitsch P, Beaver K, Olson JG (1996) Experimentally induced Bartonella henselae infections followed by challenge exposure and antimicrobial therapy in cats. Am J Vet Res 57(12):1714–1719PubMedGoogle Scholar
  223. Reis C, Cote M, Le Rhun D, Lecuelle B, Levin ML, Vayssier-Taussat M, Bonnet SI (2011) Vector competence of the tick Ixodes ricinus for transmission of Bartonella birtlesii. PLoS Negl Trop Dis 5:1186CrossRefGoogle Scholar
  224. Resto-Ruiz S, Burgess A, Anderson BE (2003) The role of the host immune response in pathogenesis of Bartonella henselae. DNA Cell Biol 22:431–440PubMedCrossRefGoogle Scholar
  225. Ridder GJ, Boedeker CC, Technau-Ihling K, Sander A (2005) Cat-scratch disease: otolaryngologic manifestations and management. Otolaryngol Head Neck Surg 132:353–358PubMedCrossRefGoogle Scholar
  226. Rie T, Anderson B, Fackelmayerc A, Autenrietha IB, Kempf VAJ (2003) Rapid and efficient transposon mutagenesis of Bartonella henselae by transposome technology. Gene 313:103–109CrossRefGoogle Scholar
  227. Riess T, Andersson SGE, Lupas A, Schaller M, Schafer A et al (2004) Bartonella adhesin a mediates a proangiogenic host cell response. J Exp Med 200:1267–1278PubMedCentralPubMedCrossRefGoogle Scholar
  228. Riess T, Raddatz G, Linke D, Schäfer A, Kempf VA (2008) Analysis of a novel insect cell culture medium-based growth for Bartonella species. Appl Environ Microbiol 74:5224–5227PubMedCentralPubMedCrossRefGoogle Scholar
  229. Ristic M, Kreier JP (1984) Family III. Anaplasmataceae Philip 1957. In: Krieg NR, Holt JC (eds) Bergey’s manual of systematic bacteriology, vol 1. Williams & Wilkins, Baltimore, pp 719–729Google Scholar
  230. Rolain JM, Foucault C, Guieu R, La Scola B, Brouqui P, Raoult D (2002) Bartonella quintana in human erythrocytes. Lancet 360:226–228PubMedCrossRefGoogle Scholar
  231. Rolain JM, Franc M, Davoust B, Raoult D (2003) Molecular detection of Bartonella quintana, B. koehlerae, B. henselae, B. clarridgeiae, Rickettsia felis, and Wolbachia pipientis in cat fleas, France. Emerg Infect Dis 9:338–342PubMedCrossRefGoogle Scholar
  232. Rolain JM, Brouqui P, Koehler JE, Maguina C, Dolan MJ, Raoult D (2004) Recommendations for treatment of human infections caused by Bartonella species. Antimicrob Agents Chemother 48:1921–1933PubMedCentralPubMedCrossRefGoogle Scholar
  233. Rolain JM, Maurin M, Raoult D (2000) Bactericidal effect of antibiotics on Bartonella and Brucella spp.: clinical implications. J Antimicrob Chemother 46:811–814PubMedCrossRefGoogle Scholar
  234. Roux V, Raoult D (1995a) The 16S-23S rRNA intergenic spacer region of Bartonella (Rochalimaea) species is longer than usually described in other bacteria. Gene 156:107–111PubMedCrossRefGoogle Scholar
  235. Roux V, Raoult D (1995b) Inter- and intraspecies identification of Bartonella (Rochalimaea) species. J Clin Microbiol 33:1573–1579PubMedCentralPubMedGoogle Scholar
  236. Roux V, Raoult D (1999) Body lice as tools for the diagnosis and surveillance or reemerging diseases. J Clin Microbiol 37:596–599PubMedCentralPubMedGoogle Scholar
  237. Roux V, Eykyn SJ, Wyllie S, Raoult D (2000) Bartonella vinsonii subsp. berkhoffii as an agent of afebrile blood culture-negative endocarditis in a human. J Clin Microbiol 38:1698–1700PubMedCentralPubMedGoogle Scholar
  238. Saenz HL, Engel P, Stoeckli MC, Lanz C, Raddatz G et al (2007) Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet 39:1469–1476PubMedCrossRefGoogle Scholar
  239. Saisongkorh W, Wootta W, Sawanpanyalert P, Raoult D, Rolain JM (2009) “Candidatus Bartonella thailandensis”: a new genotype of Bartonella identified from rodents. Vet Microbiol 139:197–201PubMedCrossRefGoogle Scholar
  240. Sanchez Clemente N, Ugarte-Gil CA, Solórzano N, Maguiña C, Pachas P, et al (2012) Bartonella bacilliformis: a systematic review of the literature to guide the research agenda for elimination PLoS Negl Trop Dis 6:e1819PubMedGoogle Scholar
  241. Sander A, Zagrosek A, Bredt W, Schiltz E, Piemont Y, Lanz C, Dehio C (2000) Characterization of Bartonella clarridgeiae flagellin (FlaA) and detection of antibodies in patients with lymphadenopathy. J Clin Microbiol 38:2943–2948PubMedCentralPubMedGoogle Scholar
  242. Sanogo YO, Zeaiter Z, Caruso G, Merola F, Shpynov S, Brouqui P, Raoult D (2003) Bartonella henselae in Ixodes ricinus ticks (Acari: Ixodida) removed from humans, Belluno Province. Italy. Emerg Infect Dis 9(3):329–332PubMedCentralPubMedCrossRefGoogle Scholar
  243. Sato S, Kabeya H, Fujinaga Y, Inoue K, Une Y, Yoshikawa Y, Maruyama S (2013) Bartonella jaculi sp. nov., Bartonella callosciuri sp. nov., Bartonella pachyuromydis sp. nov. and Bartonella acomydis sp. nov., isolated from wild Rodentia. Int J Syst Evol Microbiol 63:1734–1740PubMedCrossRefGoogle Scholar
  244. Saunders GK, Monroe WE (2006) Systemic granulomatous disease and sialometaplasia in a dog with Bartonella infection. Vet Pathol 43:391–392PubMedCrossRefGoogle Scholar
  245. Schmid MC, Scheidegger F, Dehio M, Balmelle-Devaux N, Schulein R et al (2006) A translocated bacterial protein protects vascular endothelial cells from apoptosis. PLoS Pathog 2:e115PubMedCentralPubMedCrossRefGoogle Scholar
  246. Schmincke RA (1917) Histopathologischer Befund in Roseolen der Haut bei Wolhynischem Fieber. Münch Med Wochenschr 64:961Google Scholar
  247. Schulein R, Dehio C (2002) The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection. Mol Microbiol 46:1053–1067PubMedCrossRefGoogle Scholar
  248. Schulein R, Seubert A, Gille C, Lanz C, Hansmann Y, Piémont Y, Dehio C (2001) Invasion and persistent intracellular colonization of erythrocytes: a unique parasitic strategy of the emerging pathogen Bartonella. J Exp Med 193(9):1077–1086PubMedCentralPubMedCrossRefGoogle Scholar
  249. Schulein R, Guye P, Rhomberg TA, Schmid MC, Schroder G et al (2005) A bipartite signal mediates the transfer of type IV secretion substrates of Bartonella henselae into human cells. Proc Natl Acad Sci USA 102:856–861PubMedCentralPubMedCrossRefGoogle Scholar
  250. Schulte B, Linke D, Klumpp S, Schaller M, Riess T et al (2006) Bartonella quintana variably expressed outer membrane proteins mediate vascular endothelial growth factor secretion but not host cell adherence. Infect Immun 74:5003–5013PubMedCentralPubMedCrossRefGoogle Scholar
  251. Schwartzmann WA, Patnaik M, Angulo FJ, Vusscher BR, Miller EN, Peter JB (1995) Bartonella (Rochalimaea) antibodies, dementia and cat ownership among men infected with human immunodeficiency virus. Clin Infect Dis 21:954–959CrossRefGoogle Scholar
  252. Seki N, Sasaki T, Sawabe K, Matsuoka M, Arakawa Y, Marui E, Kobayashi M (2006) Epidemiological studies on Bartonella quintana infections among homeless people in Tokyo, Japan. Jpn J Infect Dis 59:31–35PubMedGoogle Scholar
  253. Seubert A, Schulein R, Dehio C (2002) Bacterial persistence within erythrocytes: a unique pathogenic strategy of Bartonella spp. Int J Med Microbiol 291:555–560PubMedCrossRefGoogle Scholar
  254. Seubert A, Falch C, Birtles RJ, Schulein R, Dehio C (2003a) Characterization of the cryptic plasmid pBGR1 from Bartonella grahamii and construction of a versatile Escherichia coli-Bartonella spp. shuttle cloning vector. Plasmid 49:44–52PubMedCrossRefGoogle Scholar
  255. Seubert A, Hiestand R, de la Cruz F, Dehio C (2003b) A bacterial conjugation machinery recruited for pathogenesis. Mol Microbiol 49:1253–1266PubMedCrossRefGoogle Scholar
  256. Sharp JT (1968) Isolation of L forms of Bartonella bacilliformis. Exp Biol Med 128(4):1072–1075CrossRefGoogle Scholar
  257. Skerget M, Wenisch C, Daxboeck F, Krause R, Haberl R, Stuenzner D (2003) Cat or dog ownership and seroprevalence of ehrlichiosis, Q fever, and cat-scratch disease. Emerg Infect Dis 9:1337–1340PubMedCentralPubMedCrossRefGoogle Scholar
  258. Slater LN, Welch DF, Hensel D, Coody DW (1990) A newly recognized fastidious gram-negative pathogen as a cause of fever and bacteremia. N Engl J Med 323:1587–1593PubMedCrossRefGoogle Scholar
  259. Slater LN, Coody DW, Woolridge LK, Welch DF (1992) Murine antibody responses distinguish Rochalimaea henselae from Rochalimaea quintana. J Clin Microbiol 30:1722–1727PubMedCentralPubMedGoogle Scholar
  260. Spach DH, Panther LA, Thorning DR, Dunn JE, Plorde JJ, Miller RA (1992) Intracerebral bacillary angiomatosis in a patient infected with human immunodeficiency virus. Ann Intern Med 116:740–742PubMedCrossRefGoogle Scholar
  261. Spach DH, Callis KP, Paauw DS et al (1993) Endocarditis caused by Rochalimaea quintana in a patient infected with human immunodeficiency virus. J Clin Microbiol 31:692–694PubMedCentralPubMedGoogle Scholar
  262. Spach DH, Kanter AS, Daniels NA, Nowowiejski DJ, Larson AM, Schmidt RA, Brenner DJ et al (1995) Bartonella (Rochalimaea) species as a cause of apparent “culture-negative” endocarditis. Clin Infect Dis 20(4):1044–1047PubMedCrossRefGoogle Scholar
  263. Stoler MH, Bonfiglio TA, Steigbigel RT, Pereira M (1983) An atypical subcutaneous infection associated with acquired immune deficiency syndrome. Am J Clin Pathol 80:714–718PubMedGoogle Scholar
  264. Strong RP (1918) Trench fever report of commission Medical Research Committee. American Red CrossGoogle Scholar
  265. Strong RP, Tyzzer EE, Brues CT, Sellards AW, Gastiaburu JC (1913) Verruga peruviana, Oroya fever and uta. J Am Med Assoc 61:1713–1716CrossRefGoogle Scholar
  266. Strong RP, Tyzzer EE, Sellards AW (1915) Oroya fever. Second report. J Am Med Assoc 64:806–808CrossRefGoogle Scholar
  267. Stutzer B, Hartmann K (2012) Chronic bartonellosis in cats. What are the potential implications? J Feline Med Surg 14:612–621PubMedCrossRefGoogle Scholar
  268. Suksawat J, Pitulle C, Arraga-Alvarado C, Madrigal K, Hancock SI, Breitschwerdt EB (2001) Co-infection with multiple Ehrlichia species in dogs from Thailand and Venezuela with emphasis on consideration of 16S ribosomal DNA secondary structure. J Clin Microbiol 39:90–93PubMedCentralPubMedCrossRefGoogle Scholar
  269. Sweger D, Resto-Ruiz S, Johnson DP, Schmiederer M, Hawke N, Anderson B (2000) Conservation of the 17-kilodalton antigen gene within the genus Bartonella. Clin Diagn Lab Immunol 7:251–257PubMedCentralPubMedGoogle Scholar
  270. Tappero JW, Koehler JE, Berger TG, Cockerell CJ, Lee TH, Busch MP, Stites DP, Mohle-Boetani J, Reingold AL, LeBoit PE (1993) Bacillary angiomatosis and bacillary splenitis in immunocompetent adults. Ann Intern Med 118:363–365PubMedCrossRefGoogle Scholar
  271. Taye A, Chen H, Duncan K, Zhang Z, Hendrix L, Gonzalez J, Ching W (2005) Production of recombinant protein Pap31 and its application for the diagnosis of Bartonella bacilliformis infection. Ann N Y Acad Sci 1063:280–285PubMedCrossRefGoogle Scholar
  272. Tea A, Alexiou-Daniel S, Arvanitidou M, Diza E, Antoniadis A (2003) Occurrence of Bartonella henselae and Bartonella quintana in a healthy Greek population. Am J Trop Med Hyg 68:554–556PubMedGoogle Scholar
  273. Telfer S, Clough HE, Birtles LR, Bennett M, Carslake D, Helyar S, Begon M (2007) Ecological differences and coexistence in a guild of microparasites: Bartonella in wild rodents. Ecology 88(7):1841–1849PubMedCrossRefGoogle Scholar
  274. Umemori E, Sasaki Y, Amano K, Amano Y (1992) A phage in Bartonella bacilliformis. Microbiol Immunol 36:731–736PubMedCrossRefGoogle Scholar
  275. Varanat M, Broadhurst J, Linder KE, Maggi RG, Breitschwerdt EB (2012) Identification of Bartonella henselae in two cats with pyogranulomatous myocarditis and diaphragmatic myositis. Vet Pathol 49:608–611PubMedCrossRefGoogle Scholar
  276. Varela G, Vinson JW, Molina-Pasquel C (1969) Propagation of Rickettsia quintana on cell-free medium from the blood of two patients. Am J Trop Med Hyg 18:708–712PubMedGoogle Scholar
  277. Viale AM, Arakaki AK, Soncini FC, Ferreyra RG (1994) Evolutionary relationships among eubacterial groups as inferred from GroEL (chaperonin) sequence comparisons. Int J Syst Bacteriol 44:527–533PubMedCrossRefGoogle Scholar
  278. Weiss E, Dasch GA (1982) Differential characteristics of strains of Rochalimaea: Rochalimaea vinsonii sp. nov., the Canadian vole agent. Int J Syst Bacteriol 32:305CrossRefGoogle Scholar
  279. Welch DF (2005) Family II. Bartonellaceae Gieszczykiewicz 1939, 25 AL. In: Bergey’s manual of systematic bacteriology. Springer, New York, pp 362–370CrossRefGoogle Scholar
  280. Welch DF, Pickett DA, Slater LN, Steigerwalt AG, Brenner DJ (1992) Rochalimaea henselae sp. nov., a cause of septicemia, bacillary angiomatosis, and parenchymal bacillary peliosis. J Clin Microbiol 30(2):275–280PubMedCentralPubMedGoogle Scholar
  281. Welch DF, Carroll KC, Hofmeister EK, Persing DH, Robison DA, Steigerwalt AG, Brenner DJ (1999) Isolation of a new subspecies, Bartonella vinsonii subsp. arupensis, from a cattle rancher: identity with isolates found in conjunction with Borrelia burgdorferi and Babesia microti among naturally infected mice. J Clin Microbiol 37:2598–2601PubMedCentralPubMedGoogle Scholar
  282. Welch DE, Caroll KC, Hofmeister EK, Persing DH, Robson DA, Streigerwalt AG, Brenner DJ (2000) Validation of the publication of new names and new combinations previously effectively published outside the IJSB. List N 72. Int J Syst Evol Microbiol 50:3–4Google Scholar
  283. Werner JA, Feng S, Chomel BB, Hodzic E, Kasten RW, Barthold SW (2006) Cloning, characterization, and expression of Bartonella henselaep26. Clin Vaccine Immunol 13:830–836PubMedCentralPubMedCrossRefGoogle Scholar
  284. Windsor J (2001) Cat-scratch disease: epidemiology, aetiology and treatment. Br J Biomed Sci 58:101–110PubMedGoogle Scholar
  285. Woese CR (1987) Bacterial evolution. Microbiol Rev 51:221–271PubMedCentralPubMedGoogle Scholar
  286. Wong MT, Dolan MJ, Lattuada CP, Regnery RL, Garcia ML, Mokulis EC, Melcher GP et al (1995) Neuroretinitis, aseptic meningitis, and lymphadenitis associated with Bartonella (Rochalimaea) henselae infection in immunocompetent patients and patients infected with human immunodeficiency virus type 1. J Clin Microbiol 21(2):352–360Google Scholar
  287. Xu YH, Lu ZY, Ihler GM (1995) Purification of deformin, an extracellular protein synthesized by Bartonella bacilliformis which causes deformation of erythrocyte membranes. Biochim Biophys Acta 1234:173–183PubMedCrossRefGoogle Scholar
  288. Yamamoto K, Chomel BB, Kasten RW, Chang CC, Tseggai T, Decker PR, Mackowiak M, Floyd-Hawkins KA, Pedersen NC (1997) Homologous protection but lack of heterologous protection by various species and types of Bartonella in specific pathogen-free cats. Vet Immunol Immunopathol 65:191–204CrossRefGoogle Scholar
  289. Zangwill KM, Hamilton DH, Perkins BA, Regnery RL, Plikaytis BD, Hadler JL, Cartter ML, Wenger JD (1993) Cat scratch disease in Connecticut—epidemiology, risk factors, and evaluation of a new diagnostic test. N Engl J Med 329:8–13PubMedCrossRefGoogle Scholar
  290. Zbinden R, Höchli M, Nadal D (1995) Intracellular location of Bartonella henselae cocultivated with Vero cells and used for an indirect fluorescent-antibody test. Clin Diagn Lab Immunol 2:693–695PubMedCentralPubMedGoogle Scholar
  291. Zbinden R, Michael N, Sekulovski M, von Graevenitz A, Nadal D (1997) Evaluation of commercial slides for detection of immunoglobulin G against Bartonella henselae by indirect immunofluorescence. Eur J Clin Microbiol Infect Dis 16(9):648–652PubMedCrossRefGoogle Scholar
  292. Zeaiter Z, Fournier PE, Ogata H, Raoult D (2002) Phylogenetic classification of Bartonella species by comparing groEL sequences. Int J Syst Evol Microbiol 52:165–171PubMedCrossRefGoogle Scholar
  293. Zhang P, Chomel BB, Schau MK, Goo JS, Droz S et al (2004) A family of variably expressed outer-membrane proteins (Vomp) mediates adhesion and autoaggregation in Bartonella quintana. Proc Natl Acad Sci USA 101:13630–13635PubMedCentralPubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  • Cristiane Divan Baldani
    • 1
  • Huarrisson Azevedo Santos
    • 2
  • Carlos Luiz Massard
    • 3
  1. 1.Departmento de Medicina e Cirurgia VeterináriaUniversidade Federal Rural do Rio de Janeiro (UFRRJ)SeropédicaBrazil
  2. 2.Departmento de Epidemiologia e Saúde PºblicaUniversidade Federal Rural do Rio de Janeiro (UFRRJ)SeropédicaBrazil
  3. 3.Departmento de ParasitologiaUniversidade Federal Rural do Rio de Janeiro (UFRRJ)SeropédicaBrazil

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