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Encyclopedia of Pain pp 4216–4225Cite as

Visceral Pain Models, Female Reproductive Organ Pain

  • Reference work entry

  • 109 Accesses

Synonyms

Adenomyosis model; Chronic pelvic pain model; Dyspareunia model; Endometriosis model; Endometritis model; Female reproductive organ pain model; Gynecological pain model; Labor pain model; Referred abdominal muscle pain model; Vaginal hyperalgesia model; Vulvodynia model

Definition

An “animal model” of pain refers to a nonhuman animal treated in a manner to create a condition that mimics a painful human syndrome or disease. The model can then be used both to improve knowledge of mechanisms that might underlie the condition/disease and its relation to pain and to develop better treatments.

Introduction

Models of visceral pain usually refer to nonhuman animals that currently have or have had some type of pathophysiology of an internal organ. For female reproductive organs, the models are created in ways that mimic pain associated with female reproductive organs, i.e., gynecological pain. Importantly, however, as discussed below, such pain can sometimes be derived from...

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Acknowledgments

Studies cited from the authors’ laboratory were supported by NIH grant RO1 NS 11892, with the exception of Dmitrieva et al. 2012, which was supported by Bayer HealthCare Pharmaceuticals.

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Authors and Affiliations

  1. Program in Neuroscience, Florida State University, Tallahassee, FL, USA

    Karen J. Berkley & Natalia Dmitrieva

Authors
  1. Karen J. Berkley
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  2. Natalia Dmitrieva
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Corresponding author

Correspondence to Karen J. Berkley .

Editor information

Editors and Affiliations

  1. Department of Anesthesiology, Center for Pain Research, University of Pittsburgh, Pittsburgh, PA, USA

    Gerald F. Gebhart

  2. Physiologisches Institut der, Universität Würzburg, Würzburg, Germany

    Robert F. Schmidt

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Berkley, K.J., Dmitrieva, N. (2013). Visceral Pain Models, Female Reproductive Organ Pain. In: Gebhart, G.F., Schmidt, R.F. (eds) Encyclopedia of Pain. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-28753-4_4799

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