Encyclopedia of Pain

2013 Edition
| Editors: Gerald F. Gebhart, Robert F. Schmidt

Retrograde Axonal Tracer

Reference work entry
DOI: https://doi.org/10.1007/978-3-642-28753-4_201931

Definition

A substance (protein, enzyme) that is injected at the level of axonal endings. It is incorporated within the endings, then conveyed in a retrograde (antidromic) direction within the axon back to the soma. The tracer is generally colored by a histochemical reaction, with or without an earlier immune amplification reaction; see also  Retrograde Tracing Technique.

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© Springer-Verlag Berlin Heidelberg 2013