Translational Research Methods: The Value of Animal Models in Renal Research

  • Jordan Kreidberg
Living reference work entry


The use of animal models has been an essential aspect of nearly all areas of nephrological research since its earliest days. Research on kidney formation and malformation, physiology and pathophysiology, immunological injury, and tolerance or transplant rejection all depend on the use of animal experimentation. This chapter will emphasize genetic approaches that utilize animals, as this area has shown the great progress in the development of novel technologies that have had great impact in all areas of nephrology.


Embryonic Stem Cell Bacterial Artificial Chromosome Inbred Strain Polycystic Kidney Disease Microsatellite Repeat 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Children’s Hospital BostonBostonUSA

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