Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab


  • Qing Ping Dou
  • Xiao Yuan
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_985-3



Celastrol is a natural quinone methide friedelane tripterene, widely found in the plant genera Celastrus, Maytenus, and Tripterygium, all of which are present in China. For example, celastrol is one of the active components extracted from Tripterygium wilfordii Hook F, an ivy-like vine also known as “Thunder of God Vine,” which belongs to the family of Celastraceae and has been used as a natural medicine in China for hundreds of years (Fig. 1).


Androgen Receptor Tripterygium Wilfordii Chinese Traditional Medicinal Product Celastrol Treatment Glomerella Cingulata 
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© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.The Prevention Program, Barbara Ann Karmanos Cancer Institute and Department of Pathology, School of MedicineWayne State UniversityDetroitUSA
  2. 2.Research and Development Center, Wuhan Botanical GardenChinese Academy of ScienceWuhanPeople’s Republic of China