CEACAM1 Adhesion Molecule
CEACAM1 (CEA-related cell adhesion molecule 1) belongs to the CEA (carcinoembryonic antigen, CEA gene family) family of cell surface glycoproteins, a subfamily of the immunoglobulin gene superfamily. The CEA family comprises two major groups, the CEA-related molecules and the PSG (pregnancy-specific glycoprotein)-related molecules. Additionally, a number of pseudogenes have been identified. To date, 29 genes are known, which are clustered on human chromosome 19 (19q13.1-19q13.2). The CEA-related members of the CEA family display a complex expression pattern on human healthy and malignant tissues. They are linked to the cell membrane via GPI anchors, or they are transmembrane proteins with a cytoplasmatic tail. The PSG-related molecules are soluble glycoproteins; their expression is...
KeywordsBiliary Tract Disease Lumen Formation Epidermal Growth Factor Receptor Ligand Short Cytoplasmic Tail CEACAM1 Expression
- Singer BB, Lucka LK (2005) CEACAM1. UCSD-nature molecule pages. Nat Publ Group. doi:10.1038/mp.a003597.01Google Scholar