Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Adhesion

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_95-2

Definition

Cell adhesion is a dynamic process that results from specific interactions between cell surface molecules and their appropriate ligands. Adhesion can be found between adjacent cells (cell-cell adhesion) as well as between cells and the extracellular matrix (ECM) (cell-matrix adhesion). Besides keeping a multicellular organism together, cell adhesion is also a source of specific signals to adherent cells; their phenotype can thus be regulated by their adhesive interactions. In fact, most of the cell adhesion receptors were found to be involved in signal transduction. By interacting with growth factor receptors they are able to modulate their signaling efficiency. Therefore, gene expression, cytoskeletal dynamics, and growth regulation all depend, at least partially, on cell adhesive interactions (Fig. 1).

Keywords

Circulate Tumor Cell Tumor Cell Adhesion High Endothelial Venule Cadherin Expression Subendothelial Matrix 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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See Also

  1. (2012) Basement membrane. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 349. doi:10.1007/978-3-642-16483-5_537Google Scholar
  2. (2012) Cadherins. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 581–582. doi:10.1007/978-3-642-16483-5_770Google Scholar
  3. (2012) Chemotaxis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 793. doi:10.1007/978-3-642-16483-5_1081Google Scholar
  4. (2012) Extracellular matrix. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1362. doi:10.1007/978-3-642-16483-5_2067Google Scholar
  5. (2012) Glycoprotein. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1570. doi:10.1007/978-3-642-16483-5_2451Google Scholar
  6. (2012) Glycosaminoglycans. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1570. doi:10.1007/978-3-642-16483-5_2453Google Scholar
  7. (2012) Haptotaxis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1631. doi:10.1007/978-3-642-16483-5_2565Google Scholar
  8. (2012) Heparan sulfate. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1647. doi:10.1007/978-3-642-16483-5_2637Google Scholar
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  10. (2012) Proteoglycans. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3100. doi:10.1007/978-3-642-16483-5_4816Google Scholar
  11. (2012) Selectins. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3355. doi:10.1007/978-3-642-16483-5_5218Google Scholar
  12. (2012) Sialoglycoconjugates. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3402. doi:10.1007/978-3-642-16483-5_5292Google Scholar
  13. (2012) Tumor progression. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3800. doi:10.1007/978-3-642-16483-5_6046Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Friedrich Miescher InstituteBaselSwitzerland