Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Childhood Cancer and Treatment-Related Toxicities

  • Stefan K. Zöllner
  • Jeffrey A. Toretsky
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_7233-1

Definition

Treatment-related toxicities of childhood cancer encompass both the physical and non-physical burden of children and young adolescents diagnosed with cancer which result from invasive and non-invasive medical treatment modalities and the psycho-socio-economic effects of being a cancer patient, occurring during and/or after the disease-related treatment.

Risk awareness

The overall survival rates of many pediatric cancers continue to improve with each decade due to new advances in therapy. As this trend continues, the focus and importance of minimizing acute and long-term toxicity associated with treatment is paramount; significant treatment-related toxicities continue to impact the majority of children with cancer. Awareness of short- and long-term health risks is important, and careful follow-up of long-term survivors is essential. Children with cancer and their families are affected not only by the disease and treatments but also by significant effects on the child’s...

Keywords

Acute Myeloid Leukemia Hematopoietic Stem Cell Transplantation Papillary Thyroid Carcinoma Ionize Radiation Therapy Childhood Cancer 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of Pediatric Hematology and OncologyUniversity Childrens Hospital MünsterMünsterGermany
  2. 2.Department of Oncology and Pediatrics, Lombardi Comprehensive Cancer CenterGeorgetown UniversityWashingtonUSA