Exosomes, shuttling from donor cells to recipient cells, are cell-derived extracellular vesicles (EV) with 30–100 nm in diameter and dish- or classic cup-shaped morphology. Exosomes transport bioactive cargo carrying selective proteins, lipids, DNA, messenger RNAs (mRNAs), and small and large noncoding RNAs such as microRNAs (miRNAs). miRNA embedded in exosomes is termed as exosomal miRNA. Exosomal miRNAs regulate diverse biological processes in recipient cells.
Biogenesis of Exosomes and Exosomal miRNA Packaging
KeywordsRecipient Cell Extracellular Vesicle Exosome Secretion Metastatic Breast Cancer Cell Line Inhibit Breast Cancer Cell Growth
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