Colorectal Cancer Chemoprevention
Synonyms
Definition
Chemoprevention involves the use of drugs (of synthetic or natural origin) in order to delay, reverse, or prevent disease progression. The chemoprevention concept is not a new medical intervention and has been used for decades with remarkable success as part of risk reduction approaches for cardiovascular disease. Diseases with a long latency period, such as colorectal cancer, provide an ideal scenario for the application of chemopreventive strategies with a considerable potential to improve patient outcomes. However, in order to determine whether such a strategy may be truly beneficial within this paradigm, two research areas need to experience significant advances. Firstly, our understanding of the natural progression of the disease and underlying molecular and genetic changes needs to be improved further, and secondly, robust and easily measurable biomarkers need to be discovered and developed for...
Keywords
Colorectal Cancer Familial Adenomatous Polyposis Lynch Syndrome Aberrant Crypt Focus Colorectal Cancer RiskReferences
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See Also
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