Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Pancreatic Cancer Metastasis

  • Thilo Welsch
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_7204-1



Pancreatic cancer metastasis describes the process that leads to secondary malignant tumor cell growth at distant sites or organs from the parental cancer in the pancreas. Pancreatic cancer is often used as a synonym for pancreatic ductal adenocarcinoma (PDAC), which is the most frequent (>80 %) and most lethal histologic type of cancer arising in the pancreas. Other histologic types are neuroendocrine tumors of the pancreas, acinar cell carcinoma, or adenosquamous carcinoma, which are not referred to in this entry.


Pancreatic cancer is the fourth leading cause of cancer-related death in the Western world, and one main reason for the dismal prognosis is early metastasis to regional lymph nodes and distant organ sites (most frequently to the liver, peritoneum, and lung) (Iacobuzio-Donahue et al. 2009) (Fig. 1). Macroscopically,...


Pancreatic Cancer Pancreatic Ductal Adenocarcinoma Lymph Node Ratio Metastatic Process Adenosquamous Carcinoma 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Visceral, Thoracic and Vascular SurgeryTU DresdenDresdenGermany