Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Probiotics and Cancer

  • Abdul Arif Khan
  • Shahanavaj Khan
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_7195-1

Definition

Probiotics are widely used microorganisms which exert health benefits after ingestion in sufficient amount. Their role in the management of gastrointestinal health is already proven. These organisms can also contribute to the management of several diseases including cancer.

Characteristics

The word “pro” is showing “promote” and biotic indicating “life” for probiotic. The probiotic preparation with sufficient number of defined and viable microorganisms exerts positive health effects to the host. Certain patients consume probiotics for modulating intestinal microbiota for health benefits. Bacteria contribute a great share to intestine with weight up to 1 kg. The ratio of microbial to human cells is estimated to be 10:1, with the genome ratio between microbes and human as 100:1. These organisms are responsible for the production of several nutritional factors (including vitamin B, K, folate, and short chain fatty acids), maintenance of normal immune status, etc. Several...

Keywords

Irritable Bowel Syndrome Short Chain Fatty Acid Probiotic Strain Lactobacillus Acidophilus Bifidobacterium Bifidum 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Ciorba MA (2012) A gasteroenterologist’s guide to probiotics. Clin Gasteroenterol Hepatol 10(9):960–968CrossRefGoogle Scholar
  2. Khan AA, Khurshid M, Khan S, Alshamsan A (2013) Gut microbiota and probiotics: current status and their role in cancer therapeutics. Drug Dev Res 74:365–375CrossRefGoogle Scholar
  3. Patel S, Goyal A (2013) Evolving roles of probiotics in cancer prophylaxis and therapy. Probiotics Antimicro Proteins 9:31–36Google Scholar
  4. Sanders ME, Guarner F, Guerant R, Holt PR, Quigley EM, Sartor RB, Sherman PM, Mayer EA (2013) An update on the use and investigation of probiotics in health and disease. Gut 62:787–96. (1)CrossRefPubMedPubMedCentralGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.Department of PharmaceuticsCollege of Pharmacy, King Saud UniversityRiyadhSaudi Arabia