Definition
The ParaHox gene cluster is an array of homeobox genes that, similarly to Hox genes, encode transcription factors involved in specifying regional identity during embryonic development. The ParaHox gene cluster includes the CDX genes (CDX1, CDX2, CDX4) and GSX genes (GSX1, GSX2). The ParaHox gene cluster is considered as evolutionary related to the Hox gene cluster: the two gene clusters are thought to arise by duplication of a primitive ProtoHox gene cluster.
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© 2015 Springer-Verlag Berlin Heidelberg
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Gross, I. (2015). PARAHOX. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_7179-3
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DOI: https://doi.org/10.1007/978-3-642-27841-9_7179-3
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Publisher Name: Springer, Berlin, Heidelberg
Online ISBN: 978-3-642-27841-9
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