Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab


  • Margaret McLaughlin-Drubin
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_7177-3



KDM6A and KDM6B are histone demethylases that specifically demethylate the repressive histone 3 (H3) lysine 27 trimethyl mark.
  • KDM6A lysine (K)-specific demethylase 6A; UTX, ubiquitously transcribed TPR protein on the X chromosome; and ubiquitously transcribed X chromosome tetratricopeptide repeat protein

  • KDM6B lysine (K)-specific demethylase 6B; JMJD3; JmjC domain-containing protein 3; and Jumonji domain-containing protein 3

  • K...


Transcriptional Start Site Embryonic Stem Cell Differentiation Tetratricopeptide Repeat Mesoderm Differentiation Bivalent Domain 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Division of Infectious DiseasesBrigham and Womens HospitalBostonUSA