Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Photothermal Therapy

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_7097-1

Synonyms

Definition

Photothermal therapy (PTT) is a method of heat ablation in which light energy is utilized to induce localized heat within the tissue and destroy the pathologic cells. Often in practice and in order to not harm surrounding healthy tissues, the targeted diseased cells are labeled with light-absorbing nano-sized particles, which significantly increases the light energy absorption and also allows for utilizing laser lights in near-infrared (NIR) wavelengths to achieve larger penetration depths. With the aid of these nano-sized agents (i.e., nanoparticles), PTT is capable of destroying pathologic cells selectively, at larger penetration depth and with no damage to surrounding non-labeled healthy tissue.

Characteristics

Hyperthermia is a noninvasive approach for cancertherapy, whereby biological tissues are exposed to higher than normal temperatures to promote destruction of abnormal cells. PTT is...

Keywords

Photothermal Therapy Large Penetration Depth Urothelial Cancer Cell Photothermal Conversion Efficiency Local Light Intensity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Biomedical EngineeringWayne State UniversityDetroitUSA