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Brain Tumors

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Encyclopedia of Cancer

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Definition

Primary brain tumors present most commonly as meningioma or various grades of astrocytoma. Glioma which includes astrocytoma constitute 80 % of all malignant brain and central nervous system tumors. It is estimated that approximately 24,000 individuals will be diagnosed with cancer of the brain and nervous system in 2016, about 1.4 % of all newly occurring malignancies. Of those diagnosed, there will be 13 % more men than women. Primary brain and nervous system cancers will account 4 % of the estimated 596,000 cancer deaths in 2016. Based on the most recent report of the Central Brain Tumor Registry of the United States, benign tumors of the CNS arise in numbers comparable to malignant brain tumors. In children and young adults, brain tumors are responsible for 25 % of all cancer-related deaths, second only to leukemia in this age group. The estimated 5-year relative survival rate for malignant brain tumors is about 33 %, but there is much variation in survival, depending...

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References

  • Alentorn, A., et al. (2015). “Molecular profiling of gliomas: potential therapeutic implications.” Expert Rev Anticancer Ther 15(8): 955–962.

    Article  CAS  PubMed  Google Scholar 

  • American Cancer Society. Cancer Facts & Figures (2016). Atlanta, GA, The American Cancer Society

    Google Scholar 

  • Bernstein, M. and M. S. Berger (2008). Neuro-Oncology: The essentials. New York, Thieme.

    Google Scholar 

  • Ellison, D. W. (2015). “Multiple Molecular Data Sets and the Classification of Adult Diffuse Gliomas.” N Engl J Med 372(26): 2555–2557.

    Article  CAS  PubMed  Google Scholar 

  • Ostrom, Q. T., et al. (2015). CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors TCGA Data Portal Overview. The Cancer Genome Atlas. National Cancer Institute, National Human Genome Research Institute. https://tcga-data.nci.nih.gov/tcga/.

See Also

  • (2012) Anaplastic Astrocytoma. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 169. doi: 10.1007/978-3-642-16483-5_256

    Google Scholar 

  • (2012) Atypical Teratoid/Rhabdoid Tumor. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 304. doi: 10.1007/978-3-642-16483-5_454

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  • (2012) Cerebral Edema. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 750. doi: 10.1007/978-3-642-16483-5_1034

    Google Scholar 

  • (2012) Glioma. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1557. doi: 10.1007/978-3-642-16483-5_2423

    Google Scholar 

  • (2012) Glucocorticoids. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1558. doi: 10.1007/978-3-642-16483-5_2429

    Google Scholar 

  • (2012) Gorlin Syndrome. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1586. doi: 10.1007/978-3-642-16483-5_2481

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  • (2012) Lymphoma. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2124. doi: 10.1007/978-3-642-16483-5_3463

    Google Scholar 

  • (2012) Neural Stem Cells. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2478. doi: 10.1007/978-3-642-16483-5_4023

    Google Scholar 

  • (2012) P53. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2747. doi: 10.1007/978-3-642-16483-5_4331

    Google Scholar 

  • (2012) Primitive Neuroectodermal Tumor. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, pp 2988–2989. doi: 10.1007/978-3-642-16483-5_4744

    Google Scholar 

  • (2012) Radiation Therapy. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3144. doi: 10.1007/978-3-642-16483-5_4907

    Google Scholar 

  • (2012) RB1. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3189. doi: 10.1007/978-3-642-16483-5_4964

    Google Scholar 

  • (2012) Tuberous Sclerosis Syndrome. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3792. doi: 10.1007/978-3-642-16483-5_6010

    Google Scholar 

  • (2012) Vincristine. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3908. doi: 10.1007/978-3-642-16483-5_6188

    Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Translational Neuro-Oncology and Neurotherapeutics, John Wayne Cancer Institute, Providence St. John’s Health Center, Santa Monica, CA, USA

    Santhosh Kesari

  2. Departments of Pediatrics and of Genetics, Norris Cotton Cancer Center, Dartmouth Medical School, Hanover, NH, USA

    Gilbert J. Rahme, Damian A. Almiron & Mark A. Israel

Authors
  1. Santhosh Kesari
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  2. Gilbert J. Rahme
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  3. Damian A. Almiron
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  4. Mark A. Israel
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Corresponding author

Correspondence to Mark A. Israel .

Editor information

Editors and Affiliations

  1. Abt. Tumorgenetik, Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Manfred Schwab

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© 2014 Springer-Verlag Berlin Heidelberg

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Kesari, S., Rahme, G.J., Almiron, D.A., Israel, M.A. (2014). Brain Tumors. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_709-3

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  • DOI: https://doi.org/10.1007/978-3-642-27841-9_709-3

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

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