Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Ovarian Serous Carcinoma

  • Manfred Schwab
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_6967-2

Definition

Serous neoplasms are the single most frequent subtype of ovarian cancer. They show morphologic features resembling the fallopian tube epithelium. All serous neoplasms, including benign, borderline, and malignant, tend to occur bilaterally (involve both ovaries) and may be associated with psammoma bodies (concentrically laminated microscopic calcified structures). Serous carcinomas account for 60–70 % of all ovarian carcinomas. Over 60 % are bilateral and present at a high stage (FIGO stage III or IV). They typically occur in postmenopausal women, the peak age being in the sixth decade. On gross examination, serous carcinomas are not definitely distinguishable from other malignant neoplasms, but they do exhibit the usual features of malignant tumors, e.g., solid/cystic structures, friability, areas of hemorrhage, and necrosis. Microscopically, serous tumors are characterized by at least focal formation of papillary structures and slit-like spaces between the papillae. The...
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See Also

  1. (2012) Atypia. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 303. doi: 10.1007/978-3-642-16483-5_449Google Scholar
  2. (2012) FIGO. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1407. doi: 10.1007/978-3-642-16483-5_2188Google Scholar
  3. (2012) Hematoxylin and eosin. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1645. doi: 10.1007/978-3-642-16483-5_2623Google Scholar
  4. (2012) Mitosis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2342. doi: 10.1007/978-3-642-16483-5_3774Google Scholar
  5. (2012) Psammoma bodies. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3112. doi: 10.1007/978-3-642-16483-5_6927Google Scholar
  6. (2012) Serous. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3389. doi: 10.1007/978-3-642-16483-5_6936Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.German Cancer Research Center (DKFZ)HeidelbergGermany