Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Lung Cancer Epidemiology

  • Robert Kratzke
  • Michael J. Franklin
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_6893-8


Is the study of the incidence, distribution, and ultimately, the prevention and control of lung cancer within the general population.


Of all cancer types, lung cancer is the leading cause of cancer-related death worldwide, mostly in the United States (Adami et al. 2008).

Types of Lung Cancer

Approximately 95 % of primary lung cancers are carcinomas of the lung, arising from deregulated growth of epithelial cells (American Cancer Society 2014). The two major lung carcinomas are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Approximately 85–90 % of lung cancers are diagnosed as NSCLC, a heterogeneous group of malignancies consisting of three subtypes:

Adenocarcinomas account for approximately 40 % of all lung cancers. About 25–30 % of lung cancers are squamous cell carcinomas, and about 10–15 % of lung cancers are large cell carcinomas. Other subtypes of NSCLC are rare and...


Lung Cancer Small Cell Lung Cancer Carcinoid Tumor Smoking Prevalence Adenoid Cystic Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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  1. Adami HO, Hunter D, Trichopoulos D (eds) (2008) Textbook of cancer epidemiology. Oxford University Press, New YorkGoogle Scholar
  2. Albert AJ, Samet JM (2003) Epidemiology of lung cancer. Chest 123:21S4Google Scholar
  3. American Cancer Society (2014) Lung cancer (non-small cell). American Cancer Society. Available at http://www.cancer.org/acs/groups/cid/documents/webcontent/003115-pdf.pdf. Accessed 6 Nov 2014
  4. American Cancer Society (2014) Cancer facts & figures 2014. American Cancer Society, AtlantaGoogle Scholar
  5. Bain C, Feskanich D, Speizer FE et al (2004) Lung cancer rates in men and women with comparable histories of smoking. J Natl Cancer Inst 96(11):826–833CrossRefPubMedGoogle Scholar
  6. Centers for Disease Control and Prevention (2014) Current cigarette smoking among adults—United States, 2005–2012. Morb Mortal Wkly Rep 63(02):29–34. Accessed 14 Feb 2014Google Scholar
  7. Doll R, Peto R (1978) Cigarette smoking and bronchial carcinoma: dose and time relationships among regular smokers and lifelong non-smokers. J Epidemiol Community Health 32(4):303–313CrossRefPubMedPubMedCentralGoogle Scholar
  8. Edwards BK, Noone A-M, Mariotto AB, Simard EP, Boscoe FP, Henley SJ, Jemal A, Cho H, Anderson RN, Kohler BA, Eheman CR, Ward EM (2013) Annual report to the nation on the status of cancer, 1975–2010, featuring prevalence of comorbidity and impact on survival among persons with lung, colorectal, breast, or prostate cancer. External Web Site Icon CancerGoogle Scholar
  9. Ferlay J, Soerjomataram I, Ervik M et al (2013) GLOBOCAN 2012 v1.0, cancer incidence and mortality worldwide: IARC CancerBase No. 11 [Internet]. International Agency for Research on Cancer, Lyon, Available from: http://globocan.iarc.fr Google Scholar
  10. Giovino GA (2002) Epidemiology of tobacco use in the United States. Oncogene 21(48):7326–7340CrossRefPubMedGoogle Scholar
  11. Howlader N, Noone AM, Krapcho M, Garshell J, Miller D, Altekruse SF, Kosary CL, Yu M, Ruhl J, Tatalovich Z, Mariotto A, Lewis DR, Chen HS, Feuer EJ, Cronin KA (eds) (2014) SEER cancer statistics review, 1975–2011. National Cancer Institute, Bethesda, http://seer.cancer.gov/csr/1975_2011/, based on Nov 2013 SEER data submission, posted to the SEER web siteGoogle Scholar
  12. International Agency for Research on Cancer (2003) IARC monographs on the evaluation of carcinogenic risk in humans, vol 83, Tobacco smoking and involuntary smoking. IARC Press, LyonsGoogle Scholar
  13. McLaughlin JK, Hrubec Z, Blot WJ, Fraumeni JF Jr (1995) Smoking and cancer mortality among U.S. veterans: a 26-year follow-up. Int J Cancer 60(2):190–193CrossRefPubMedGoogle Scholar
  14. Nicholson WJ, Perkel G, Selikoff IJ (1982) Occupational exposure to asbestos: population at risk and projected mortality – 1980–2030. Am J Ind Med 3(3):259–311CrossRefPubMedGoogle Scholar
  15. Rugo HS, Fischman ML (1997) Occupational cancer. In: LaDou J (ed) Occupational and environmental medicine. Appleton & Lange, Stamford, pp 235–271Google Scholar
  16. Steenland K, Loomis D, Shy C et al (1996) Review of occupational lung carcinogens. Am J Ind Med 29(5):474–490CrossRefPubMedGoogle Scholar
  17. U.S. Cancer Statistics Working Group (2014) United States Cancer Statistics: 1999–2011 incidence and mortality web-based report. Department of Health and Human Services, Centers for Disease Control and Prevention, and National Cancer Institute, AtlantaGoogle Scholar
  18. U.S. Department of Health and Human Services (2001) Women and smoking. A report of the surgeon general – 2001. U.S. Department of Human Services, CDC. Washington, DCGoogle Scholar
  19. Zhang H, Cai B (2003) The impact of tobacco on lung health in China. Respirology 8(1):17–21CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Division of Hematology, Oncology and TransplantationUniversity of MinnesotaMinneapolisUSA