Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Bone Tumors

  • Michael J. Klein
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_689-3

Synonyms

Definition

Bone tumors are space-occupying lesions arising in bone that are usually derived from primitive connective tissue elements.

They constitute a diverse group of neoplasms that are collectively less common than those of almost all other body sites. Malignant primary bone tumors have an approximate incidence one new malignant bone tumor per 100,000 individuals per year. Since the incidence of benign bone tumors is about half that of malignant tumors, the average aggregate incidence of all bone tumors is about one in 67,000 persons per year.

With a few notable exceptions, bone tumors have a predilection for individuals in the second and third decade; there is a second, smaller peak of incidence in the sixth and seventh decade. In most large series of bone tumors, there is a slight male predominance. Each tumor type has a characteristic range age, skeletal distribution, and sometimes sex and racial predilection.

Characteristics

Etiology

While...

Keywords

Bone Tumor Fibrous Dysplasia Giant Cell Tumor Malignant Bone Tumor Bone Sarcoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. Dorfman HD, Czerniak B, Kotz R (2002) WHO classification of tumours of bone: introduction. In: Fletcher CDM, Bridge JA, Hogendoorn DCW, Mertens F (eds) Pathology and genetics of tumours of soft tissue and bone, WHO Classification of Tumours of Soft Tissue and Bone (IARC: Lyon 2013). pp. 384–385, 390–392.Google Scholar
  2. Klein MJ (2005) Radiographic correlation in orthopedic pathology. Adv Anat Pathol 12(4):155–179CrossRefPubMedGoogle Scholar
  3. Klein MJ, Siegal GP (2006) Osteosarcoma: anatomic and histological variants. Am J Clin Pathol 125(4):555–581CrossRefPubMedGoogle Scholar
  4. Unni KK, Inwards CY, Bridge JA (2005) Tumors of the bones and joints, AFIP Atlas of tumor pathology, 4th series, fascicle 2. ARP Press, Silver SpringGoogle Scholar

See Also

  1. (2012) Dedifferentiation. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1072. doi:10.1007/978-3-642-16483-5_1547Google Scholar
  2. (2012) Ectodermal. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1209. doi:10.1007/978-3-642-16483-5_1808Google Scholar
  3. (2012) Enchondroma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1221. doi:10.1007/978-3-642-16483-5_1866Google Scholar
  4. (2012) Endodermal. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1232. doi:10.1007/978-3-642-16483-5_1877Google Scholar
  5. (2012) Fibrous dysplasia. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1403. doi:10.1007/978-3-642-16483-5_2183Google Scholar
  6. (2012) Hemangioendothelioma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1640. doi:10.1007/978-3-642-16483-5_2612Google Scholar
  7. (2012) Hemangioma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1640. doi:10.1007/978-3-642-16483-5_2613Google Scholar
  8. (2012) Idiopathic bone infarction. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1804. doi:10.1007/978-3-642-16483-5_2942Google Scholar
  9. (2012) Mesoderm. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2240. doi:10.1007/978-3-642-16483-5_3645Google Scholar
  10. (2012) Paget disease. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2758. doi:10.1007/978-3-642-16483-5_4345Google Scholar
  11. (2012) Rothmund-Thomson syndrome. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3322. doi:10.1007/978-3-642-16483-5_5128Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Pathology and Laboratory MedicineHospital for Special SurgeryNew YorkUSA