Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Prostate Cancer Radionuclide Therapy

  • Yiyan Liu
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_6797-2


Radionuclide therapy involves the attempt to kill cancer cells and the surrounding affected tissue with radioactive materials. The advantages of radionuclide therapy include the fact that, depending on the form of treatment, it is either noninvasive or much less invasive than surgery. Bone-seeking radiopharmaceuticals or radionuclides are used to treat prostate cancer if it has spread to the bones. The drug is injected intravenously and is absorbed into the bones. It is a single outpatient treatment that can be administered in the doctor’s office.


Bone metastases are the most common cause of pain in advanced prostate cancer patients resulting from tumor infiltration and extension of the periosteal membranes, mechanical instability, tumor-induced cytokines, stimulating factors, and tumor spread from the bone to contiguous neurological structures. The management of bone pain continues to be a major therapeutic challenge and involves a multidisciplinary...


Radionuclide Therapy Beta Particle Penetration Range Shared Toilet Bone Pain Palliation 
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See Also

  1. (2012) Cytopenia. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1056. doi: 10.1007/978-3-642-16483-5_1484Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of RadiologyNew Jersey Medical School, Rutgers UniversityNew BrunswickUSA