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Metastatic Breast Cancer Experimental Therapeutics

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Synonyms

Breast adenocarcinoma; Breast carcinoma; Malignant breast carcinoma

Definition

Experimental therapies for metastatic breast cancer can be defined as novel interventions directed toward the more effective treatment of secondary, progressively growing tumors distant from the primary site of the breast. Experimental therapies may include newly developed drug agents or may be different modalities for existing agents, such as the novel indication of a drug in the setting of breast cancer or the combination of approved single agents.

Characteristics

Breast cancer affects one in four women and is the second leading cause of cancer mortality among women in the United States. Globally, breast cancer is the leading cause of cancer mortality in women. Approximately 1 % of all cases of breast cancer occur in men. The majority of mortality associated with the disease is due to the advanced, metastatic form of breast cancer, characterized by progressively growing tumors distant from the...

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References

  • Cardoso F, Castiglione M (2009) Locally recurrent or metastatic breast cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 20(Suppl 4):15–18

    PubMed  Google Scholar 

  • Kataja V, Castiglione M (2009) Primary breast cancer: ESMO clinical recommendations for diagnosis, treatment and follow-up. Ann Oncol 20(Suppl 4):10–14

    PubMed  Google Scholar 

  • Tkaczuk KH (2009) Review of the contemporary cytotoxic and biologic combinations available for the treatment of metastatic breast cancer. Clin Ther 31(Pt 2):2273–2289

    Article  PubMed  Google Scholar 

  • Wong ST (2009) Emerging treatment combinations: integrating therapy into clinical practice. Am J Health Syst Pharm 66:S9–S14

    Article  CAS  PubMed  Google Scholar 

See Also

  • (2012) Adjuvant. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 75. doi:10.1007/978-3-642-16483-5_107

    Google Scholar 

  • (2012) Allogeneic. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 138. doi:10.1007/978-3-642-16483-5_194

    Google Scholar 

  • (2012) EGF. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1211. doi:10.1007/978-3-642-16483-5_1824

    Google Scholar 

  • (2012) Exemestane. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1357. doi:10.1007/978-3-642-16483-5_6752

    Google Scholar 

  • (2012) Interleukin. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1892. doi:10.1007/978-3-642-16483-5_3094

    Google Scholar 

  • (2012) Lapatinib. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 1980. doi:10.1007/978-3-642-16483-5_3277

    Google Scholar 

  • (2012) Monoclonal Antibody. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2367. doi:10.1007/978-3-642-16483-5_6842

    Google Scholar 

  • (2012) Proliferation. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3004. doi:10.1007/978-3-642-16483-5_4766

    Google Scholar 

  • (2012) Progesterone Receptor. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 2990. doi:10.1007/978-3-642-16483-5_4754

    Google Scholar 

  • (2012) Sunitinib. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3562. doi:10.1007/978-3-642-16483-5_5575

    Google Scholar 

  • (2012) Vaccine Therapy. In: Schwab M (ed) Encyclopedia of Cancer, 3rd edn. Springer Berlin Heidelberg, p 3879. doi:10.1007/978-3-642-16483-5_6147

    Google Scholar 

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Correspondence to Alexandra Silveira .

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Silveira, A. (2015). Metastatic Breast Cancer Experimental Therapeutics. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_6794-2

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  • DOI: https://doi.org/10.1007/978-3-642-27841-9_6794-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

  • eBook Packages: Springer Reference Biomedicine and Life SciencesReference Module Biomedical and Life Sciences

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