Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Colorectal Cancer Clinical Oncology

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_6311-2

Synonyms

Definition

Colon cancer refers to malignant neoplasia of the large intestine. The demarcation line to the more distal rectal cancer is defined as being proximal to 16 cm of the anocutaneous line.

Characteristics

Due to the slow development of precursor lesions in the form of adenomatous polyps or dysplastic lesions, no other tumor offers as many possibilities and as much time for preventive measures. Diagnosis of colon cancer in early stages highly increases the probability of curative resection. A 5-year survival rate of patients diagnosed with stage one colon cancer (limited to the bowel wall) is 90 %, which is decreased to 35–60 % in patients with a positive nodal status (stage III) and drops to less than 10 % in the metastatic disease (stage IV).

Screening Strategies for the Average-Risk Population

Early colon cancer detection programs have been suggested to asymptomatic population of a certain age....

Keywords

Familial Adenomatous Polyposis Fecal Occult Blood Test Multivisceral Resection Left Colic Artery Colon Cancer Surgery 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access

References

  1. Kronborg O, Fenger C, Olsen J et al (1996) Randomised study of screening for colorectal cancer with faecal-occult-blood test. Lancet 348:1467–1471CrossRefPubMedGoogle Scholar
  2. Levin B, Bond JH (1996) Colorectal cancer screening: recommendations of the U.S. preventive services task force. Gastroenterology 111:1381–1384CrossRefPubMedGoogle Scholar
  3. Rex DK, Cummings OW, Helper DJ et al (1996) 5-Year incidence of adenomas after negative colonoscopy in asymptomatic average-risk persons. Gastroenterology 111:1178–1181CrossRefPubMedGoogle Scholar
  4. Rex DK, Rahmani EY, Hasemann JH et al (1997) Relative sensitivity of colon of colorectal cancer in clinical practice. Gastroenterology 112:17–23CrossRefPubMedGoogle Scholar
  5. Selby JV, Friedmann GD, Quesenberry CP et al (1992) A case-control study of screening sigmoidoscopy and mortality from colorectal cancer. N Engl J Med 326:653–657CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Helios klinik, Allgemein- und ViszeralchirurgieBochumGermany