Bioavailability of Nutrients
Refers to the fraction of a mineral nutrient intake that is biologically available to meet the essential metabolic and/or structural functions associated with that mineral nutrient in the body. Bioavailability incorporates the concepts of absorption, distribution, metabolic transformation (where necessary to meet biological function), and excretion. In some circumstances the main component of bioavailability is absorption across the gastrointestinal wall, so that sometimes the term bioavailability may be used interchangeably with absorption.
Bioavailability of Drugs
Refers to the percentage of drug that is detected in the systemic circulation after its administration. Losses can be attributed to an inherent lack of absorption/passage into the systemic circulation and/or to metabolic clearance. Detection of drug can be accomplished pharmacodynamically or pharmacokinetically. Oral bioavailability is associated with orally administered drugs.
KeywordsCancer Research Nutrient Intake Systemic Circulation Biological Function Structural Function
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