Synonyms
Definition
Bile duct neoplasms are classified as benign and malignant tumors of the cells comprising the bile ducts of the liver, which include the bile duct epithelial cells and the connective tissues supporting the bile duct structure.
Characteristics
The biliary system is comprised of intra- and extrahepatic bile ducts. The function of this system is to transport bile from the liver to the duodenum where bile aids in the digestion of dietary fats. Bile ducts have a tube or vessel-like appearance. The interior of the ducts is lined with columnar epithelial cells, which have been termed cholangiocytes. Cholangiocytes are surrounded by a subepithelial layer of tough connective tissue, which contains a scant number of smooth muscle cells. Also, within this connective tissue layer resides a population of mucous cells. The biliary system is surrounded by a network of nerves, blood vessels, and lymphatics. Bile duct neoplasms are an extremely...
References
Alpini G, Prall RT, LaRusso NF (2001) The pathobiology of biliary epithelia. In: Arias IM, Boyer JL, Chisari FV, Fausto N, Jakoby W, Schachter D, Shafritz DA (eds) The liver; biology and pathobiology, 4th edn. Lippincott Williams & Wilkins, Philadelphia, pp 421–435
Anthony PP (2000) Tumors of the hepatobiliary system. In: Fletcher CDM (ed) Diagnostic histopathology of tumors. Churchill Livingstone, London, pp 411–460
Jain D, Sarode V, Abdul-Karim F et al (2000) Evidence for the neoplastic transformation of Von-Meyenburg complexes. Am J Surg Pathol 24:1131–1139
Lazaridis KN, Gores GJ (2005) Cholangiocarcinoma. Gastroenterology 128:1655–1667
Nakanuma Y, Sasaki M, Ishikawa A et al (2002) Biliary papillary neoplasm of the liver. Histol Histopathol 17:851–856
See Also
(2012) Bile. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 397. doi:10.1007/978-3-642-16483-5_614
(2012) Bile duct. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 399. doi:10.1007/978-3-642-16483-5_616
(2012) Cholangiocytes. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 820. doi:10.1007/978-3-642-16483-5_1109
(2012) Cholestasis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 821. doi:10.1007/978-3-642-16483-5_1115
(2012) Chronic ulcerative colitis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 856. doi:10.1007/978-3-642-16483-5_1160
(2012) Clonorchis sinensis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 885. doi:10.1007/978-3-642-16483-5_1223
(2012) Gallstones. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1493. doi:10.1007/978-3-642-16483-5_2308
(2012) Liver cancer. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2063. doi:10.1007/978-3-642-16483-5_3393
(2012) Primary sclerosing cholangitis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2988. doi:10.1007/978-3-642-16483-5_4742
(2012) Stroma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3541. doi:10.1007/978-3-642-16483-5_5532
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Glaser, S.S., Alpini, G. (2014). Bile Duct Neoplasms. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_620-7
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DOI: https://doi.org/10.1007/978-3-642-27841-9_620-7
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