Tunicamycin is an antibiotic identified and isolated from the fermentation broth of Streptomyces lysosuperificus. Since the antibiotic interferes with the formation of viral and cellular surface coats, it was termed “tunicamycin” after the Latin word “tunica” for coats.
Structure and Function
KeywordsEndoplasmic Reticulum Stress Unfold Protein Response Newcastle Disease Virus Mouse Embryonic Fibroblast Endoplasmic Reticulum Kinase
- Takatsuki A, Tamura G (1982) Inhibition of glycoconjugate biosynthesis by tunicamycin. In: Tamura G (ed) Tunicamycin. Japan Scientific Societies Press, Tokyo, pp 35–70Google Scholar