Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Tobacco Carcinogenesis

  • Stephen S. Hecht
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_5846-2


Refers to cancer induction by tobacco products and their constituents in laboratory animals and humans.


Tobacco Products and Human Cancer

Worldwide tobacco use continues to be immense and pervasive. According to estimates by the World Health Organization, there are about 1.3 billion smokers in the world and millions of smokeless tobacco users. Cigarette smoking causes well over one million cancer deaths annually worldwide and accounts for 26 % of all cancer mortality in developed countries. In addition to lung cancer (Lung Cancer and Smoking Behavior), cigarette smoking causes the following types of cancer: oral cavity cancer, larynx cancer, esophageal cancer, nasal cavity cancer, stomach cancer, liver cancer, renal cancer, ureter cancer, cervix cancer, and myeloid leukemia. Secondhand tobacco smoke causes lung cancer in nonsmokers, although the risk is less than in smokers. Smokeless tobacco products, such as moist snuff used orally, are accepted causes of...


Polycyclic Aromatic Hydrocarbon Cigarette Smoke Tobacco Product Smokeless Tobacco Oral Cavity Cancer 
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Copyright information

© Springer-Verlag Berlin Heidelberg 2015

Authors and Affiliations

  1. 1.The Cancer CenterUniversity of MinnesotaMinneapolisUSA