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Surface Plasmon Resonance

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Encyclopedia of Cancer

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Definition

Surface plasmon resonance (SPR) is one of several optical phenomena known to occur on two-dimensional metal surfaces (typically gold or silver films) when a total internal reflection of incident light occurs at the interface of two different substances, one with a high refraction index and the other with a low refraction index. The SPR biosensor, which exploits the SPR phenomenon, is a label-free and surface-sensitive spectroscopic system, which utilizes measured changes in the local refraction index upon adsorption. This sensor may be applicable to disease diagnostics and high-throughput screening (HTS) in drug discovery, as well as to studies of biomolecular interaction.

Characteristics

Detection Principle of SPR Biosensor

Surface plasmon polaritons (SPPs), which are also referred to more simply as surface plasmons (SPs), are longitudinal and collective oscillations of electrons occurring on a metal-dielectric interface. The frequencies of these longitudinal oscillations...

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References

  • Englebienne P, Van Hoonacker A, Verhas M (2003) Surface plasmon resonance: principles, methods and applications in biomedical sciences. Spectroscopy 17:255–273

    Article  CAS  Google Scholar 

  • Jonsson U, Fagerstam L, Ivarsson B et al (1991) Real-time biospecific interaction analysis using surface plasmon resonance and a sensor chip technology. Biotechniques 11:620–627

    CAS  PubMed  Google Scholar 

  • Ro HS, Koh BH, Jung SO et al (2006) Surface plasmon resonance imaging protein arrays for analysis of triple protein interactions of HPV, E6, E6AP, and p53. Proteomics 6:2108–2111

    Article  CAS  PubMed  Google Scholar 

See Also

  • (2012) Biosensor. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 415. doi: 10.1007/978-3-642-16483-5_646

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  • (2012) Electrospray ionization. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 1216. doi: 10.1007/978-3-642-16483-5_1846

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  • (2012) Label-free analysis. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 1967. doi: 10.1007/978-3-642-16483-5_3257

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  • (2012) Matrix-assisted laser desorption/ionization-time of flight. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 2187. doi: 10.1007/978-3-642-16483-5_3555

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  • (2012) P53. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer Berlin Heidelberg, p 2747. doi: 10.1007/978-3-642-16483-5_4331

    Google Scholar 

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Author information

Authors and Affiliations

  1. BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, Yuseong, Daejeon, Republic of Korea

    Bong Hyun Chung†, Moonil Kim & Yong-Beom Shin

Authors
  1. Bong Hyun Chung†
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  2. Moonil Kim
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  3. Yong-Beom Shin
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Corresponding author

Correspondence to Yong-Beom Shin .

Editor information

Editors and Affiliations

  1. Abt. Tumorgenetik, Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Manfred Schwab

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Chung†, B.H., Kim, M., Shin, YB. (2015). Surface Plasmon Resonance. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_5595-2

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  • DOI: https://doi.org/10.1007/978-3-642-27841-9_5595-2

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

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