Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Squamous Cell Carcinoma

  • W. Andrew Yeudall
Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_5462-2

Synonyms

Definition

Squamous cell carcinoma is a malignant tumor arising from non-glandular lining or covering epithelia.

Characteristics

Squamous cell carcinoma (SCC) is an invasive tumor which may present at numerous body sites, including the skin, ocular epithelium, oral cavity, alimentary tract, anogenital region, larynx, and bronchial epithelium. Thus, the incidence of SCC lesions varies with site. Estimates from the National Cancer Institute indicate that over one million new cases of skin SCC (skin carcinogenesis) will be diagnosed in the USA in 2007, representing 16 % of all types of skin cancer. Similarly, approximately 40,000 new cases of head and neck SCC (comprising the oral cavity, pharynx, larynx) occur each year. Squamous cell carcinoma is also one variety of non-small cell lung cancer, the annual incidence of which is 170,000. Anogenital SCC, comprising lesions of the cervix, vulva, vagina, penis, and anus, is less frequent. Approximately 23,600...

Keywords

Epidermal Growth Factor Receptor Squamous Cell Carcinoma Oral Squamous Cell Carcinoma Mutant Epidermal Growth Factor Receptor Actinic Keratosis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

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See Also

  1. (2012) Cellular atypia. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 743. doi:10.1007/978-3-642-16483-5_1015Google Scholar
  2. (2012) Daughter cells. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1061. doi:10.1007/978-3-642-16483-5_1520Google Scholar
  3. (2012) Epidermodysplasia verruciformis (EV). In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1279. doi:10.1007/978-3-642-16483-5_1934Google Scholar
  4. (2012) Erythroplakia. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 1313–1314. doi:10.1007/978-3-642-16483-5_1999Google Scholar
  5. (2012) FHIT. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1394. doi:10.1007/978-3-642-16483-5_2168Google Scholar
  6. (2012) Field cancerization. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1406. doi:10.1007/978-3-642-16483-5_2185Google Scholar
  7. (2012) Leukoplakia. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2028. doi:10.1007/978-3-642-16483-5_3332Google Scholar
  8. (2012) Loss of heterozygosity. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 2075–2076. doi:10.1007/978-3-642-16483-5_3415Google Scholar
  9. (2012) Lymphatic system. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2120. doi:10.1007/978-3-642-16483-5_3450Google Scholar
  10. (2012) Malignant progression. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 2149–2150. doi:10.1007/978-3-642-16483-5_3517Google Scholar
  11. (2012) P53. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2747. doi:10.1007/978-3-642-16483-5_4331Google Scholar
  12. (2012) Tobacco. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 3716–3717. doi:10.1007/978-3-642-16483-5_5844Google Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Department of Oral BiologyCollege of Dental Medicine, Georgia Regents UniversityAugustaUSA