Encyclopedia of Cancer

Living Edition
| Editors: Manfred Schwab

Skin Cancer

Living reference work entry
DOI: https://doi.org/10.1007/978-3-642-27841-9_5339-8

Synonyms

Definition

Skin cancer refers to primary cancers of the skin, i.e., cells originating from one of the three skin layers transform into cancer cells and grow into a tumor mass in loco. Thus, this definition excludes skin metastases from other cancers, i.e., malignant cells from another primary cancer (e.g., kidney or stomach cancer) were deposited into the skin and form a lump. This also applies to most of the hematological malignancies (leukemias and lymphomas) with the exception of the primary cutaneous lymphoma where malignant lymphocytic cells primarily reside in the skin.

Characteristics

Skin Structure and Cancer Frequency

The skin consists of three layers. The epidermis (epi: on top) comprises the most outer layer of human skin and lies on top of the dermis. The dermis (syn.: cutis) comprises the middle layer of the skin and is separated from the epidermis by the basal membrane. The most inner layer of the skin below the dermis...

Keywords

Skin Cancer Basal Cell Carcinoma Cutaneous Melanoma Nucleotide Excision Repair Merkel Cell Carcinoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

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See Also

  1. (2004) Lipoma. In: Levine N, Levine CC (eds) Dermatology therapy: A to Z essentials. Springer, Berlin/Heidelberg, pp 357–358. doi:10.1007/3-540-29668-9_1643Google Scholar
  2. (2004) Liposarcoma. In: Levine N, Levine CC (eds) Dermatology therapy: A to Z essentials. Springer, Berlin/Heidelberg, p 358. doi:10.1007/3-540-29668-9_1647Google Scholar
  3. (2004) Melanoma. In: Levine N, Levine CC (eds) Dermatology therapy: A to Z essentials. Springer, Berlin/Heidelberg, p 379. doi:10.1007/3-540-29668-9_1757Google Scholar
  4. (2004) Merkel cell carcinoma. In: Levine N, Levine CC (eds) Dermatology therapy: A to Z essentials. Springer, Berlin/Heidelberg, pp 382–383. doi:10.1007/3-540-29668-9_1769Google Scholar
  5. (2004) Xeroderma pigmentosum. In: Levine N, Levine CC (eds) Dermatology therapy: A to Z essentials. Springer, Berlin/Heidelberg, pp 621–622. doi:10.1007/3-540-29668-9_2910Google Scholar
  6. (2006) UV signature mutations. In: Ganten D et al (eds) Encyclopedic reference of genomics and proteomics in molecular medicine. Springer, Berlin/Heidelberg, p 1973. doi:10.1007/3-540-29623-9_9093Google Scholar
  7. (2008) p16 INK4 (CDKN2A). In: Rédei GP (ed) Encyclopedia of genetics, genomics, proteomics and informatics. Springer, Netherlands, p 1421. doi:10.1007/978-1-4020-6754-9_12100Google Scholar
  8. (2008) Nucleotide excision repair. In: Rédei GP (ed) Encyclopedia of genetics, genomics, proteomics and informatics. Springer, Netherlands, p 1378. doi:10.1007/978-1-4020-6754-9_11677Google Scholar
  9. (2012) Angiosarcoma. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 187. doi:10.1007/978-3-642-16483-5_279Google Scholar
  10. (2012) Basal cell nevus syndrome. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, pp 345–346. doi:10.1007/978-3-642-16483-5_530Google Scholar
  11. (2012) Dermatofibrosarcoma protuberans. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1087. doi:10.1007/978-3-642-16483-5_7044Google Scholar
  12. (2012) Familial cancer syndrome. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 1374. doi:10.1007/978-3-642-16483-5_2109Google Scholar
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  15. (2012) Melanin. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 2203. doi:10.1007/978-3-642-16483-5_3602Google Scholar
  16. (2012) Reciprocal translocation. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3204. doi:10.1007/978-3-642-16483-5_4989Google Scholar
  17. (2012) Ultraviolet radiation. In: Schwab M (ed) Encyclopedia of cancer, 3rd edn. Springer, Berlin/Heidelberg, p 3841. doi:10.1007/978-3-642-16483-5_6102Google Scholar
  18. Hescheler J, Fleischmann BK (2006) Stem cells: an overview. In: Ganten D et al (eds) Encyclopedic reference of genomics and proteomics in molecular medicine. Springer, Berlin/Heidelberg, pp 1799–1802. 10.1007/3-540-29623-9_4450CrossRefGoogle Scholar
  19. Raschke C, Elsner P (2010) Skin aging: a brief summary of characteristic changes. In: Farage MA, Miller KW, Maibach HI (eds) Textbook of aging skin. Springer, Berlin/Heidelberg, pp 37–43. doi:10.1007/978-3-540-89656-2_5CrossRefGoogle Scholar
  20. Wicking C, Evans TM (2006) Hedgehog signalling. In: Ganten D et al (eds) Encyclopedic reference of genomics and proteomics in molecular medicine. Springer, Berlin/Heidelberg, pp 749–752. doi:10.1007/3-540-29623-9_4290CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2014

Authors and Affiliations

  1. 1.Clinic for Dermatology and VenereologyUniversity Medical Center RostockRostockGermany