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Programmed Cell Death 4

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References

  • Asangani IA, Rasheed SA, Nikolova DA et al (2008) MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene 27:2128–2136

    Article  CAS  PubMed  Google Scholar 

  • Binia A, Van Stiphout N, Liang L et al (2013) A polymorphism affecting MYB binding within the promoter of the PDCD4 gene is associated with severe asthma in children. Hum Mutat 34:1131–1139

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Blees JS, Bokesch HR, Rubsamen D et al (2012) Erioflorin stabilizes the tumor suppressor Pdcd4 by inhibiting its interaction with the E3-ligase β-TrCP1. Plos One 7:e46567

    Google Scholar 

  • Cmarik JL, Min H, Hegamyer G et al. (1999) Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc Natl Acad Sci 96:14037–14042

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dorrello NV, Peschiaroli A, Guardavaccaro D et al (2006) S6K1- and βTRCP-mediated degradation of PDCD4 promotes protein translation and cell growth. Science 314:467–471

    Article  CAS  PubMed  Google Scholar 

  • Fehler O, Singh P, Haas A et al (2014) An evolutionarily conserved interaction of tumor suppressor protein Pdcd4 with the poly(A)-binding protein contributes to translation suppression by Pdcd4. Nucleic Acids Res 42:11107–11118

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Frankel LB, Christoffersen NR, Jacobsen A et al (2008) Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem 283:1026–1033

    Article  CAS  PubMed  Google Scholar 

  • Hilliard A, Hilliard B, Zheng S-J et al (2006) Translational regulation of autoimmune inflammation and lymphoma genesis by programmed cell death 4. J Immunol 177:8095–8102

    Article  CAS  PubMed  Google Scholar 

  • Goke A, Goke R, Knolle A et al. (2002) DUG is a novel homologue of translation initiation factor 4G that binds elf4A. Biochem Biophys Res Commun 297:78–82

    Article  CAS  PubMed  Google Scholar 

  • Jin H, Kim TH, Hwang S-K et al (2006) Aerosol delivery of urocanic acid-modified chitosan/programmed cell death 4 complex regulated apoptosis, cell cycle, and angiogenesis in lungs of K-ras null mice. Mol Cancer Ther 5:1041–1049

    Article  CAS  PubMed  Google Scholar 

  • Jurisicova A, Latham KE, Casper RF and Varmuza SL (1998) Expression and Regulation of genes associated with cell death during murine preimplantation embryo development. Mol Reprod Dev 51:243–253

    Article  CAS  PubMed  Google Scholar 

  • Liwak U, Thakor N, Jordan LE et al (2012) Tumor suppressor PDCD4 represses internal ribosome entry site-mediated translation of antiapoptotic proteins and is regulated by S6 kinase 2. Mol Cell Biol 32:1818–1829

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Matsuhashi S, Hamajima H, Xia JH et al (2014) Control of a tumor suppressor PDCD4: degradation mechanisms of the protein in hepatocellular carcinoma cells. Cell Signal 26:603–610

    Article  CAS  PubMed  Google Scholar 

  • Nakashima M, Hamajima H, Xia J et al (2010) Regulation of tumor suppressor PDCD4 by novel protein kinase C isoforms. Biochim Biophys Acta 1803:1020–1027

    Google Scholar 

  • Schmid T, Jansen AP, Baker AR et al (2008) Translation inhibitor Pdcd4 is targeted for degradation during tumor promotion. Cancer Res 68:1254–1260

    Article  CAS  PubMed  Google Scholar 

  • Shibahara K, Asano M, Ishida Y et al. (1995) Isolation of novel mouse gene MA-3 that is induced upon programmed cell death. Gene 166:297–301

    Article  CAS  PubMed  Google Scholar 

  • Soejima H, Miyoshi O, Yoshinaga H et al. (1999) Assignment of the programmed cell death 4 gene (PDCD4) to human chromosome band 10q24 by in situ hybridization. Cytogenet Cell Genet 87:113–114

    Article  CAS  PubMed  Google Scholar 

  • Yang H-S, Matthews CP, Clair T et al (2006) Tumorigenesis suppressor Pdcd4 down-regulates mitogen-activated protein kinase kinase kinase kinase 1 expression to suppress colon carcinoma cell invasion. Mol Cell Biol 26:1297–1306

    Article  PubMed  PubMed Central  Google Scholar 

  • Zhang H, Ozaki I, Mizuta T et al (2006) Involvement of programmed cell death 4 in transforming growth factor-beta1-induced apoptosis in human hepatocellular carcinoma. Oncogene 25:6101–6112

    Article  CAS  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Internal Medicine, Saga Medical School, Saga University, Saga, Japan

    Sachiko Matsuhashi

  2. Health Administration Center, Saga Medical School, Saga University, Saga, Japan

    Iwata Ozaki

Authors
  1. Sachiko Matsuhashi
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  2. Iwata Ozaki
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Corresponding author

Correspondence to Sachiko Matsuhashi .

Editor information

Editors and Affiliations

  1. Abt. Tumorgenetik, Deutsches Krebsforschungszentrum, Heidelberg, Germany

    Manfred Schwab

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© 2015 Springer-Verlag Berlin Heidelberg

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Matsuhashi, S., Ozaki, I. (2015). Programmed Cell Death 4. In: Schwab, M. (eds) Encyclopedia of Cancer. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-27841-9_4761-3

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  • DOI: https://doi.org/10.1007/978-3-642-27841-9_4761-3

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Online ISBN: 978-3-642-27841-9

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