Pheochromocytomas are rare neuroendocrine tumors. The name phios (dusky), chroma (color), and cytoma (tumor) refers to the color of the tumor cells when stained with chromium salts. Catecholamine-producing neuroendocrine cells are consequently known as chromaffin cells. Some authors restrict the use of pheochromocytoma to tumors of the adrenal medulla, while others use the term more broadly to include paraganglioma. The defining characteristic of pheochromocytoma in clinical practice is the autonomous production of catecholamines (Whiting and Doogue 2009). Sympathetic paraganglial tissue (chromaffin) is mainly located in the adrenal medulla but also in prevertebral and paravertebral thoracoabdominal and pelvic paraganglia or ganglia in the ovary, testis, vagina, urethra, prostate, bladder or liver, and the Zuckerkandl organ (Erlic and Neumann 2009).
Pheochromocytoma is a rare tumor with an approximate incidence of two to...
KeywordsMultiple Endocrine Neoplasia Type Renal Clear Cell Carcinoma Adrenal Incidentaloma Malignant Pheochromocytoma Adrenal Pheochromocytoma
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