Living reference work entry
Paclitaxel is an anticancer agent derived from the North America Pacific yew tree (Taxus brevifolia) that is used in the treatment of a number of common malignancies including lung, ovarian, and breast cancer.
Paclitaxel is a cancer chemotherapeutic agent that is widely used for several types of malignancies (Fig. 1a, b). It is a natural product produced from the Pacific yew tree. While first isolated from the bark of the Pacific yew, it is now commonly synthesized from a compound obtained from yew needles or cell culture systems.
KeywordsTubulin Polymerization Guanosine Triphosphate Tubulin Dimer Taxane Class Taxus Brevifolia
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